IL-1 beta/IL-1F2 Antibody AF-201-NA from R&D Systems, a Bio-Techne Brand

Product Specs
ItemIL-1 beta/IL-1F2 Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $519.00Supplier Page View Company Product Page
Catalog NumberAF-201-NA
Conjugate/TagUnconjugated
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. See Certificate of Analysis for details. *Small pack size (-SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
HostGoat
IsotypeIgG
Quantity100 ug (also 25 ug)
ApplicationsWB, ICC, IHC, IHC-p, DB, FA, ISH, Neut
ClonalityPolyclonal
ConcentrationLYOPH
PurityAntigen Affinity-purified
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution
ImmunogenE. coli-derived recombinant human IL-1ß/IL-1F2, Ala117-Ser269, Accession # NP_000567
NCBI Full Gene Nameinterleukin 1 beta
ReactivityAmphibian,Canine,Human,Lizard,Mouse,Primate - Macaca mulatta (Rhesus Macaque)
TargetIL-1 beta/IL-1F2
NCBI Gene AliasesIL1F2, IL1-BETA, IL-1, IL1beta

Specifications/Features

Available conjugates: Available conjugates: Unconjugated

Specificity: Detects human IL-1ß/IL-1F2 in direct ELISAs and Western blots.

Sizes Available: 100 ug (also 25 ug)

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Soyeom-Jetong mixture attenuates NLRP3 inflammasome-mediated inflammationFrontiers in PharmacologyJune 16, 2026Qianying Ye, Sojung Lee, Yeon-Cheol Park, Myung-Seo Kim, Wonnam Kim, Jong-Sik Jin, Dong-Keun Kim, Seoyeon Jang, Sumin Lee, Nahyun Lee, et al.(sc-5286) was procured from Santa Cruz Biotechnology. Human IL-1β (AF-401-NA) and mouse IL-1β antibodies (AF-201-NA) were purchased from R&D Systems. LPS from Porphyromonas gingivalis (Ultrapure) (tlrl-ppglps), nigericin

(2) Cofilin-1 is a redox-sensitive guard of the NLRP3 inflammasomeNature immunologyMay 1, 2026Park YH, Batu ED, Matthiasardottir B, Kim Y, Akkaya-Ulum YZ, Kastner DL, Chae JJ.Thermo Fisher Scientific). Lysates and supernatants were analyzed by immunoblot with antibodies to human IL-1β (AF-201-NA, R&D Systems); mouse IL-1β (AF-401-NA, R&D Systems); cofilin-1 (sc-33779, rabbit polyclonal; sc-53934,

(3) HDAC3 activates endothelial NLRP3 inflammasome and promotes atherosclerosis via inhibiting the acetylation of specificity protein 1Cell death and differentiationMay 1, 2026Chen L, Zhang W, Chen H, Zhang Y, Guo B, Yang L, Yin C, Zuo Q, Ren L, Bai L, et al.

(4) Human non-canonical inflammasomes activate CASP3 to limit intracellular Salmonella replication in macrophagesPLOS PathogensApril 27, 2026Madhura Kulkarni, Christopher M. Bourne, Ashutosh B. Mahale, Patrick M. Exconde, Cecelia Murphy, Haley T. Goodrow, Sofia Cervantes, Matilda Kardhashi, Mirai Kambayashi, William Yoo, et al.CASP7 (Cell Signaling Tech, 12827S), GSDME (Abcam, ab215191), hIL-1β Goat Polyclonal Ab (R&D systems, AF-201-NA), hIL-18 Goat Ab (R&D systems, af2548), CASP8 (Cell Signaling Tech, 4790S), CASP9 (Cell Signaling Tech,

(5) Thymelaea hirsuta (L.) Endl. extract attenuates NLRP3 inflammasome activation via modulation of ATPase activityFront PharmacolApril 15, 2026Seongjong Lee, Seoyeon Jang, Hangyeol Lee, Ali Khorchani, Abdelhamid Khaldi, Mi Jin Lee, Dong Keun Yi, Soo-Yong Kim, Sangho Choi, Hyungseok Seo, et al.Cell Signaling Technology (United States). Antibodies specific for human IL-1β (AF-401-NA) and mouse IL-1β (AF-201-NA) were purchased from R&D Systems (United States). Highly cross-adsorbed secondary antibody against mouse IgG (H + L

(6) Galectin-3 Promotes Graft Injury via NLRP3 Pyroptosis in Steatotic Liver Transplantation: A Therapeutic Target for Donor OptimizationJ Clin Transl HepatolMarch 24, 2026Xianwu Yang, Shirui Huang, Ruisi Ma, Zhihui Zhu, Yingquan Zhuo, Jiafei Yang, Jun Du, Huajian GuAbcam, ab307668), Caspase-1 (1:1,000, Cell Signaling Technology, #2225), IL-1β (1:500, R&D Systems, AF-201-NA), phospho–NF-κB p65 (p–NF-κB) (1:1,000, Cell Signaling Technology, #3033), GSDMD (1:1,000, Abcam, ab209845),

(7) Fibromodulin selectively accelerates myofibroblast apoptosis in cutaneous wounds by enhancing interleukin 1β signalingNature communicationsApril 12, 2025Jiang W, Pang X, Ha P, Li C, Chang GX, Zhang Y, Bossong LA, Ting K, Soo C, Zheng Z.Scientific)65. Antibodies used for Western blotting include goat anti-human IL-1 beta/IL-1F2 antibody (AF-201-NA, R&D systems, Minneapolis, MN; 0.1 μg/mL), rabbit anti-glyceraldehyde-3-phosphate dehydrogenase (GAPDH)

(8) Chemical Tools Based on the Tetrapeptide Sequence of IL-18 Reveals Shared Specificities between Inflammatory and Apoptotic Initiator CaspasesbioRxiv : the preprint server for biologyFebruary 27, 2025Bourne CM, Raniszewski NR, Kulkarni M, Exconde PM, Liu S, Yost W, Wrong TJ, Patio RC, Mahale A, Kardhashi M, et al.polyclonal Ab,Cell Signaling Tech,Cat#4450S; RRID:AB_1950386 hIL-1β Goat Polyclonal Ab,R&D systems,Cat# AF-201-NA; RRID:AB_354387 hIL-18 Goat Polyclonal Ab,R&D systems,Cat# AF2548; RRID:AB_562603 PARP Rabbit polyclonal

(9) Post-acute sequelae of SARS-CoV-2 cardiovascular symptoms are associated with trace-level cytokines that affect cardiomyocyte functionNature microbiologyDecember 1, 2024Sinclair JE, Vedelago C, Ryan FJ, Carney M, Redd MA, Lynn MA, Grubor-Bauk B, Cao Y, Henders AK, Chew KY, et al.

(10) Comparison of Different Keratinocyte Cell Line Models for Analysis of NLRP1 Inflammasome ActivationBiomoleculesNovember 8, 2024Wang T, Yazdi AS, Panayotova-Dimitrova D.

(11) Vaccinia virus F1L blocks the ribotoxic stress response to subvert ZAKα-dependent NLRP1 inflammasome activationEuropean journal of immunologyOctober 1, 2024Szymanska I, Bauernfried S, Komar T, Hornung V.#AL177), anti-caspase-1 (Adipogen #Bally-1), anti-GSDMD (Novusbio #NBP2-33422), anti-IL-1β (R&D Systems #AF-201-NA), anti-NLRP1 (BioLegend #9F9B12), anti-p38α (Cell Signaling Technology #9217S), anti-phospho-p38 (Cell Signaling Technology

(12) Euphorbia factor L2 alleviated gouty inflammation by specifically suppressing both the priming and activation of NLRP3 inflammasomeInternational immunopharmacologySeptember 10, 2024Li Y, Zhuang Y, Chen Y, Wang G, Tang Z, Zhong Y, Zhang Y, Wu L, Ji X, Zhang Q, et al.

(13) UK5099 Inhibits the NLRP3 Inflammasome Independently of its Long‐Established Target Mitochondrial Pyruvate CarrierAdvanced ScienceSeptember 1, 2024Linyu Ran, Miao Chen, Jihui Ye, Song Zhang, Zhibing Luo, Tengfei Bai, Chenchen Qian, Quan Zhou, Mengtian Shan, Yong Chu, et al.autoradiographic film. Primary antibodies used were Mouse IL‐1β (AF‐401‐NA) (1:800) (R&D system); Human IL‐1β (AF‐201‐NA) (1:800) (R&D system); Caspase‐1 p10 (ab179515) (1:1000) (Abcam); Mouse Cleaved Gasdermin D (10 137)

(14) Targeting IL-1 controls refractory pityriasis rubra pilarisScience advancesJuly 5, 2024Schmauch E, Severin Y, Xing X, Mangold A, Conrad C, Johannsen P, Kahlenberg JM, Mellett M, Navarini A, Nobbe S, et al.

(15) SARM1 regulates pro-inflammatory cytokine expression in human monocytes by NADase-dependent and -independent mechanismsiScienceJune 21, 2024Ryoichi Sugisawa, Katharine A. Shanahan, Gavin M. Davis, Gavin P. Davey, Andrew G. BowieRRID:AB_2490257" Caspase 1 p20,Cell Signaling Technology,"Cat# 4199, RRID:AB_1903916" IL-1β,R&D Systems,"Cat# AF-201-NA, RRID:AB_354387" GSDMD,Sigma-Aldrich,"Cat# HPA044487, RRID:AB_2678957" β-actin,Sigma-Aldrich,"Cat#

(16) Anti‐inflammatory effect of Trichospira verticillata via suppression of the NLRP3 inflammasome in neutrophilic asthmaJournal of Cellular and Molecular MedicineApril 26, 2024Hyeyun Yang, Gunwoo Park, Sojung Lee, Sumin Lee, YeJi Kim, Nelson A. Zamora, Dong‐Keun Yi, Soo‐Yong Kim, Chun Whan Choi, Sangho Choi, et al.Santa Cruz Biotechnology (Santa Cruz, CA, USA). Mouse IL‐1β (AF‐401‐NA) and human IL‐1β antibodies (AF‐201‐NA) were purchased from R&D Systems (Minneapolis, MN, USA). Caspase‐1 (A0964) was purchased from ABclonal Technology

(17) Guarea microcarpa C. DC. extract inhibits NLRP3 inflammasome by suppressing its ATPase activityJournal of ethnopharmacologyApril 6, 2024Lee S, Yun S, Yang H, Lee N, Kim Y, Lee S, Zamora NA, Montero SS, Yi DK, Kim SY, et al.

(18) Type I interferon regulates interleukin-1beta and IL-18 production and secretion in human macrophagesLife Sci AllianceMarch 25, 2024Rodrigo Díaz-Pino, Gillian I Rice, Diego San Felipe, Tamar Pepanashvili, Paul R Kasher, Tracy A Briggs, Gloria López-Castejónanalysis and their final concentrations were as follows: anti-human IL-1β (0.1 μg/ml, goat polyclonal, AF-201-NA; R&D Systems) and anti-β-actin HRP (0.2 μg/ml, mouse monoclonal, A3854; Sigma-Aldrich). Cell cultures

(19) Aiouea padiformis extract exhibits anti-inflammatory effects by inhibiting the ATPase activity of NLRP3Sci RepMarch 4, 2024Sumin Lee, Qianying Ye, Hyeyun Yang, Sojung Lee, YeJi Kim, Nahyun Lee, Darwin Gonzalez-Cox, Dong-Keun Yi, Soo-Yong Kim, Sangho Choi, et al.purchased from Santa Cruz Biotechnology (Santa Cruz, CA, USA). Human IL-1β (AF-401-NA), mouse IL-1β (AF-201-NA) antibodies, and mouse IL-18 DuoSet ELISA kit (DY7625-05) were purchased from R&D Systems (Minneapolis,

(20) Interleukin-1β/Interleukin (IL)-1-Receptor-Antagonist (IL1-RA) Axis in Invasive Bladder Cancer-An Exploratory Analysis of Clinical and Tumor Biological SignificanceInternational journal of molecular sciencesFebruary 19, 2024Vukovic M, Chamlati JM, Hennenlotter J, Todenhöfer T, Lütfrenk T, Jersinovic S, Tsaur I, Stenzl A, Rausch S.

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IL-1 beta/IL-1F2 Antibody

IL-1 beta/IL-1F2 Antibody

IL-1 beta/IL-1F2 Antibody

IL-1 beta/IL-1F2 Antibody

IL-1 beta/IL-1F2 Antibody

IL-1 beta/IL-1F2 Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (110)

Reviews

IL-1 beta/IL-1F2 Antibody from R&D Systems, a Bio-Techne Brand

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