TLR3 Antibody AF1487 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemTLR3 Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $499.00Supplier Page View Company Product Page
Catalog NumberAF1487
NCBI Gene AliasesIMD83, CD283, IIAE2
ApplicationsFunctional Assay Control,Immunoprecipitation,Western Blot,Neutralization,Immunocytochemistry
HostGoat
Conjugate/TagUnconjugated
IsotypeIgG
TargetTLR3
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
ReactivityHuman
Quantity100 ug (also 25 ug)
NCBI Full Gene Nametoll like receptor 3
ClonalityPolyclonal
ImmunogenMouse myeloma cell line NS0-derived recombinant human TLR3, Lys27-Ser711, Accession # O15455
ConcentrationLYOPH
PurityAntigen Affinity-purified
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Available conjugates: Unconjugated

Specificity: Detects human TLR3 in direct ELISAs and Western blots.

Sizes Available: 100 ug (also 25 ug)

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) The Chromosome 19 miRNA cluster guards trophoblasts against overacting innate immunityCommun BiolOctober 30, 2025Jean-Francois Mouillet, Yingshi Ouyang, Elena Sadovsky, Vinoth K. Kothandan, Heather L. Sorenson, Logan J. Badeau, Saumendra N. Sarkar, Tianjiao Chu, Alexander Sorkin, Yoel Sadovskystandard procedures. Membranes were immunoblotted with a mouse monoclonal TLR3 antibody (0.2 μg/ml, #AF1487, R&D Systems, Minneapolis, MN, USA). The blots were processed for chemiluminescence using the WesternBright

(2) Distinct Effects of Respiratory Viral Infection Models on miR-149-5p, IL-6 and p63 Expression in BEAS-2B and A549 Epithelial CellsCellsMay 26, 2024Nafeesa Shahdab, Christopher Ward, Philip M. Hansbro, Stephen Cummings, John S. Young, Fatemeh Moheimani(Cell Signaling Technology, 67825, Danvers, MA, USA), anti-TLR3 antibody (R&D systems, Bio-techne, AF1487, Abingdon, UK), anti-TLR2 antibody (R&D systems, Bio-techne, AF2616), anti-GAPDH antibody (Abcam, ab9483,

(3) Increased expression of toll-like receptor 3, an anti-viral signaling molecule, and related genes in Alzheimer's disease brainsExperimental neurologyNovember 1, 2018Walker DG, Tang TM, Lue LF.cellular localization of immunoreactivity using a goat polyclonal antibody to TLR-3 (R&D Systems – AF1487) in formaldehyde-fixed brain sections. As listed in Table 2, different TLR-3 antibodies were tested

(4) Surface Toll-like receptor 3 expression in metastatic intestinal epithelial cells induces inflammatory cytokine production and promotes invasivenessThe Journal of biological chemistrySeptember 15, 2017Bugge M, Bergstrom B, Eide OK, Solli H, Kjønstad IF, Stenvik J, Espevik T, Nilsen NJ.h. TLR3 blocking experiments HT29 cells were pretreated with polyclonal anti-TLR3 antibody (R&D Systems, AF1487, 15 or 5 μg/ml) or control goat IgG (R&D Systems, AB-108-C, 15 μg/ml) for 1 h before stimulation with

(5) CHK1 and RAD51 activation after DNA damage is regulated via urokinase receptor/TLR4 signalingCell death & diseaseSeptember 29, 2016Narayanaswamy PB, Tkachuk S, Haller H, Dumler I, Kiyan Y.(sc-32233) were from Santa Cruz Biotechnology (Dallas, TX, USA); PLAUR (AF807), TLR1 (AF1475), TLR3 (AF1487), and TLR5 (MAB6704) from R&D Systems (Minneapolis, MN, USA). For immunocytochemistry γ-H2AX (#9718)

(6) Poly(I:C) Induces Human Lung Endothelial Barrier Dysfunction by Disrupting Tight Junction Expression of Claudin-5PloS oneJanuary 1, 2016Huang LY, Stuart C, Takeda K, D'Agnillo F, Golding B.purchased from Cell Signaling Technology (CST, Danvers, MA). Goat polyclonal anti-human TLR3 (catalog #AF1487) was purchased from R&D Systems (Minneapolis, MN). Rabbit polyclonal anti-human TRIF (catalog #ALX-215-016-R200)

(7) Proteolytic processing regulates Toll-like receptor 3 stability and endosomal localizationThe Journal of biological chemistrySeptember 21, 2012Qi R, Singh D, Kao CC.

(8) Herpes simplex virus encephalitis in a patient with complete TLR3 deficiency: TLR3 is otherwise redundant in protective immunityThe Journal of experimental medicineSeptember 26, 2011Guo Y, Audry M, Ciancanelli M, Alsina L, Azevedo J, Herman M, Anguiano E, Sancho-Shimizu V, Lorenzo L, Pauwels E, et al.

(9) Viral double-strand RNA-binding proteins can enhance innate immune signaling by toll-like Receptor 3PloS oneJanuary 1, 2011Lai Y, Yi G, Chen A, Bhardwaj K, Tragesser BJ, Rodrigo A Valverde, Zlotnick A, Mukhopadhyay S, Ranjith-Kumar CT, Kao CC.

(10) LL37 and cationic peptides enhance TLR3 signaling by viral double-stranded RNAsPloS oneJanuary 1, 2011Lai Y, Adhikarakunnathu S, Bhardwaj K, Ranjith-Kumar CT, Wen Y, Jordan JL, Wu LH, Dragnea B, San Mateo L, Kao CC.

(11) Oxidative stress enhances toll-like receptor 3 response to double-stranded RNA in airway epithelial cellsAmerican journal of respiratory cell and molecular biologyJune 1, 2010Koarai A, Sugiura H, Yanagisawa S, Ichikawa T, Minakata Y, Matsunaga K, Hirano T, Akamatsu K, Ichinose M.

(12) Activation of Toll-like receptor 3 augments myofibroblast differentiationAmerican journal of respiratory cell and molecular biologyJune 1, 2009Sugiura H, Ichikawa T, Koarai A, Yanagisawa S, Minakata Y, Matsunaga K, Hirano T, Akamatsu K, Ichinose M.

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Human TLR3 Antibody

TLR3 Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (12)

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TLR3 Antibody from R&D Systems, a Bio-Techne Brand

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