Human IL-29/IFN-lambda 1 Antibody AF1598 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemHuman IL-29/IFN-lambda 1 Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $519.00Supplier Page View Company Product Page
Catalog NumberAF1598
NCBI Gene AliasesIL29, IL-29
ApplicationsBioassay,ELISA Development,Immunohistochemistry,Western Blot,Neutralization
Conjugate/TagUnconjugated
Quantity100 ug (also 25 ug)
ReactivityHuman,Mouse
HostGoat
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
TargetIL-29/IFN-lambda 1
IsotypeIgG
NCBI Full Gene Nameinterferon lambda 1
ClonalityPolyclonal
ImmunogenMouse myeloma cell line NS0-derived recombinant human IL-29/IFN-lambda 1, Gly20-Thr200, Accession # Q8IU54
ConcentrationLYOPH
PurityAntigen Affinity-purified
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Unconjugated

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Alendronate partially rescues the periodontal defects in OIM mouse model of osteogenesis imperfectaScientific reportsJanuary 2, 2025Chen PJ, Wang K, Lin MH, Sharma R, Kalajzic Z, O'Brien M, Yadav S.used for immunohistochemistry: goat polyclonal anti-sclerostin (1:100, R&D Systems, Minneapolis, MN, AF1598), goat polyclonal anti-periostin (1:100, R&D Systems, AF2955), goat polyclonal anti-sclerostin (SOST,

(2) The E3 ligase subunit FBXO45 binds the interferon-λ receptor and promotes its degradation during influenza virus infectionThe Journal of biological chemistryDecember 1, 2022Tsai M, Osman W, Adair J, ElMergawy R, Chafin L, Johns F, Farkas D, Elhance A, Londino J, Mallampalli RK.and IFN-γ (BioLegend, 570206). Neutralizing antibody are as follows: anti-IL-29/IFN-λ1 (R&D systems, AF1598); normal goat IgG control (R&D systems, AB108C). Cell cultures and reagents Human bronchial epithelial

(3) Diverse susceptibilities and responses of human and rodent cells to orthohantavirus infection reveal different levels of cellular restrictionPLoS neglected tropical diseasesOctober 1, 2022Gallo G, Kotlik P, Roingeard P, Monot M, Chevreux G, Ulrich RG, Tordo N, Ermonval M.

(4) Replication of Human Norovirus RNA in Mammalian Cells Reveals Lack of Interferon ResponseJournal of virologyOctober 1, 2016Qu L, Murakami K, Broughman JR, Lay MK, Guix S, Tenge VR, Atmar RL, Estes MK.type I IFNs, goat anti-IL-29 (IFN-␭1) with cross-reactivity to IL-28A (IFN-␭2) and IL-28B (IFN-␭3) (AF1598; R&D Systems) at 1:100, goat anti-IL-10 receptor ␤ (IL10R2) (AF874; R&D Systems) at 1:100, sheep anti-IL-28

(5) The Effect of Chronic Hepatitis B Virus Infection on BDCA3+ Dendritic Cell Frequency and FunctionPloS oneJanuary 1, 2016van der Aa E, Buschow SI, Biesta PJ, Janssen HL, Woltman AM.

(6) Parainfluenza Virus 3 Blocks Antiviral Mediators Downstream of the Interferon Lambda Receptor by Modulating Stat1 PhosphorylationJournal of virologyDecember 30, 2015Eberle KC, McGill JL, Reinhardt TA, Sacco RE.and IL-28B (5259-IL). Anti-human IL-29 (hIL-29)/ IFN-␭1 antibody was used for blocking experiments (AF1598; R&D Systems). Western blotting was performed with the following antibodies from Cell Signaling: Stat1

(7) Sangassou virus, the first hantavirus isolate from Africa, displays genetic and functional properties distinct from those of other murinae-associated hantavirusesJournal of virologyApril 1, 2012Klempa B, Witkowski PT, Popugaeva E, Auste B, Koivogui L, Fichet-Calvet E, Strecker T, Ter Meulen J, Krüger DH.recombinant proteins were incubated with 1 ␮g/well of anti-IFN-␭1 or anti-IFN-␤ antibodies (catalog no. AF1598 or AF814, respectively; R&D Systems) for 1 h at room temperature. The resulting mixture was then added

(8) Dobrava-Belgrade hantavirus from Germany shows receptor usage and innate immunity induction consistent with the pathogenicity of the virus in humansPloS oneJanuary 1, 2012Popugaeva E, Witkowski PT, Schlegel M, Ulrich RG, Auste B, Rang A, Krüger DH, Klempa B.virus or recombinant proteins were incubated with 1 µg/well of anti-IFN-λ1 or anti-IFN-β (R&D Systems, AF1598 and AF814, respectively) for 1 hour at room temperature. The resulting mixture was then added to A549 cells

(9) Adenoviruses-mediated transduction of human oesophageal carcinoma cells with the interferon-λ genes produced anti-tumour effectsBritish journal of cancerOctober 25, 2011Li Q, Kawamura K, Okamoto S, Fujie H, Numasaki M, Namba M, Nagata M, Shimada H, Kobayashi H, Tagawa M.

(10) New World hantaviruses activate IFNlambda production in type I IFN-deficient vero E6 cellsPloS oneJune 17, 2010Prescott J, Hall P, Acuna-Retamar M, Ye C, Wathelet MG, Ebihara H, Feldmann H, Hjelle B.recombinant proteins with the indicated concentrations of anti-IL29, anti-IL28A, or anti-IFNβ (R&D Systems, AF1598, AF1587 or AF814, respectively) for 0.5 h at room temp. The resulting mixture was then added to cells

(11) Respiratory virus induction of alpha-, beta- and lambda-interferons in bronchial epithelial cells and peripheral blood mononuclear cellsAllergyMarch 1, 2009Khaitov MR, Laza-Stanca V, Edwards MR, Walton RP, Rohde G, Contoli M, Papi A, Stanciu LA, Kotenko SV, Johnston SL.

(12) Human TLR-7-, -8-, and -9-mediated induction of IFN-alpha/beta and -lambda Is IRAK-4 dependent and redundant for protective immunity to virusesImmunityNovember 1, 2005Yang K, Puel A, Zhang S, Eidenschenk C, Ku CL, Casrouge A, Picard C, von Bernuth H, Senechal B, Plancoulaine S, et al.IFN-λ ELISA was developed in the laboratory. Plates were coated with 1 μg/ml of anti-human IFN-λ mAb (AF1598, R&D Systems) overnight at 4°C, and the IFN-λ levels in the supernatant were estimated with a secondary

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IL-29/IFN-lambda 1 Antibody

Human IL-29/IFN-lambda 1 Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (12)

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Human IL-29/IFN-lambda 1 Antibody from R&D Systems, a Bio-Techne Brand

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