Mouse/Rat MMP-2 Antibody AF1488 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemMouse/Rat MMP-2 Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $499.00Supplier Page View Company Product Page
Catalog NumberAF1488
Quantity100 ug (also 25 ug)
ApplicationsELISA Development (Capture),Zymography,Immunohistochemistry,Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
Conjugate/TagUnconjugated
ConcentrationLYOPH
PurityAntigen Affinity-purified
HostGoat
ReactivityHuman,Mouse,Rat,Transgenic Mouse,Zebrafish
IsotypeIgG
TargetMMP-2
Antibody TypePrimary Antibodies
NCBI Gene AliasesClg4a, GelA, MMP-2
NCBI Full Gene Namematrix metallopeptidase 2
ClonalityPolyclonal
ImmunogenMouse myeloma cell line NS0-derived recombinant mouse MMP-2, Ile34-Cys662, Accession # P33434
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Unconjugated

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Microinjection of angiotensin II into zebrafish embryos induces transient dilation and elastin disruption of the dorsal aortaPhysiological reportsFebruary 1, 2025Tanifuji S, Uchida K, Kawahara G, Nakamura T, Iida S, Hayashi YK, Yokoyama U.Thermo Fisher Scientific, Waltham, MA, USA), L‐plastin (ab210099; Abcam, Cambridge, UK) and MMP‐2 (AF1488; R&D Systems, Minneapolis, MN, USA). Biotinylated mouse, rabbit, or goat antibody (Vectastain Elite

(2) A novel monomeric amyloid β-activated signaling pathway regulates brain development via inhibition of microgliaeLifeDecember 5, 2024Kwon HJ, Santhosh D, Huang Z.

(3) Cysteine Leukotriene Receptor Antagonist—Montelukast—Treatment Improves Experimental Abdominal Aortic Aneurysms in MiceCardiovascular TherapeuticsNovember 27, 2024Kexin Li, Meng Li, Panpan Wei, Kangli Tian, Haole Liu, Weilai Fu, Haiwen Hou, Yajie Chen, Baohui Xu, Yankui Li, et al.#, 102402; BioLegend) was used to mark the mural neovessels. Primary Abs against MMP2 (1:200; Cat #, AF1488, R&D Systems, Minneapolis, MN) and MMP9 (1:200; Cat #, AF909, R&D Systems) were also used to measure

(4) Differences in Acute Expression of Matrix Metalloproteinases-9, 3, and 2 Related to the Duration of Brain Ischemia and Tissue Plasminogen Activator Treatment in Experimental StrokeInternational journal of molecular sciencesAugust 30, 2024Wang D, Saleem S, Sullivan RD, Zhao T, Reed GL.

(5) HMGB2 is a potential diagnostic marker and therapeutic target for liver fibrosis and cirrhosisHepatol CommunNovember 6, 2023Yi Huang, Suthat Liangpunsakul, Swetha Rudraiah, Jing Ma, Santosh K. Keshipeddy, Dennis Wright, Antonio Costa, Diane Burgess, Yuxia Zhang, Nazmul Huda, et al.Lamin A/C (#4777), and α-SMA (#14968). Antibodies against metalloproteinases (MMP)2 (#AF980), MMP9 (#AF1488), and TIMP1 (#AF909) were obtained from R&D Systems (Minneapolis, MN). An anti-HA antibody and an anti-beta

(6) HMGB2 is a potential diagnostic marker and therapeutic target for liver fibrosis and cirrhosisHepatology CommunicationsNovember 6, 2023Yi Huang, Suthat Liangpunsakul, Swetha Rudraiah, Jing Ma, Santosh K. Keshipeddy, Dennis Wright, Antonio Costa, Diane Burgess, Yuxia Zhang, Nazmul Huda, et al.Lamin A/C (#4777), and α-SMA (#14968). Antibodies against metalloproteinases (MMP)2 (#AF980), MMP9 (#AF1488), and TIMP1 (#AF909) were obtained from R&D Systems (Minneapolis, MN). An anti-HA antibody and an anti-beta

(7) Loss of Bone Morphogenetic Protein-9 Reduces Survival and Increases MMP Activity After Myocardial InfarctionJACC. Basic to translational scienceOctober 1, 2023Bhave S, Esposito M, Swain L, Qiao X, Martin G, Wadhwa S, Everett K, Kapur NK.Abcam), BMP-9 (MAB3209; R&D Systems), endoglin (AF1320; R&D Systems), MMP-9 (AF909; R&D Systems), MMP2 (AF1488; R&D Systems), Flt-1 (Fms related receptor tyrosine kinase 1) (AF471; R&D Systems), vascular endothelial

(8) C-reactive protein deficiency ameliorates experimental abdominal aortic aneurysmsFrontiers in immunologyJanuary 1, 2023Fu Y, Liu H, Li K, Wei P, Alam N, Deng J, Li M, Wu H, He X, Hou H, et al.Biolegend Inc, San Diego, CA, USA), goat anti-mouse polyclonal antibodies against MMP2 (1:200, Cat#: AF1488, R&D Systems) and MMP9 (1:200, Cat#: AF909, R&D Systems), a biotinylated goat anti-rat secondary antibody

(9) Genetic deficiency of protein inhibitor of activated STAT3 suppresses experimental abdominal aortic aneurysmsFrontiers in cardiovascular medicineJanuary 1, 2023Fu W, Liu H, Wei P, Xia C, Yu Q, Tian K, Li Y, Liu E, Xu B, Miyata M, et al.and MMP9 were assessed by immunostaining using goat anti-mouse polyclonal antibodies against MMP2 (AF1488) and MMP9 (AF909) (R & D Systems, Minneapolis, MN, United States) (Cite your JIR article). The expression

(10) Inflammatory Role of Milk Fat Globule-Epidermal Growth Factor VIII in Age-Associated Arterial RemodelingJournal of the American Heart AssociationSeptember 6, 2022Ni L, Liu L, Zhu W, Telljohann R, Zhang J, Monticone RE, McGraw KR, Liu C, Morrell CH, Garrido-Gil P, et al.,Santa Cruz Biotechnology,Sc‐8439,,1:50 MCP1,R&D Systems,AF479,1:200, MFG‐E8,R&D Systems,AF2805,1:1000, MMP2,R&D Systems,AF1488,1:500, MT1‐MMP,Thermo Fisher Scientific,PA5‐16514,1:500, NF‐κB p65,Santa Cruz Biotechnology,sc‐8008,1:500, p‐NF‐κB

(11) Kunming mouse strain is less susceptible to elastase-induced abdominal aortic aneurysmsAnimal models and experimental medicineFebruary 1, 2022Liu H, Tian K, Xia C, Wei P, Xu B, Fu W, Li Y, Li Y, Bai L, Wang R, et al.cells per aortic cross‐section at 200× magnification. Matrix metalloproteinase 2 (MMP2; 1:200; Cat #, AF1488, R&D Systems, Minneapolis, MN) and MMP9 (1:200; Cat #, AF909, R&D Systems) expression levels were also

(12) Matrix metalloproteinases activation in Toxocara canis induced pulmonary pathogenesisJournal of microbiology, immunology, and infection = Wei mian yu gan ran za zhiDecember 1, 2021Lu CY, Lai SC, Lee HH, Chien HT, Lan KP, Chen KM.

(13) Tendon and motor phenotypes in the Crtap^-/- mouse model of recessive osteogenesis imperfectaeLifeMay 26, 2021Grol MW, Haelterman NA, Lim J, Munivez EM, Archer M, Hudson DM, Tufa SF, Keene DR, Lei K, Park D, et al.GGATGGTGAAGTTGGCTACAGG-3’. Immunohistochemistry Immunohistochemistry was performed using anti-αSMA (Abcam, ab5694, 1:200), anti-MMP2 (R and D Systems, AF1488, 1:400), and anti-phospho-NFκB p65 (Ser536) (Cell Signaling (93H1), #3033, 1:20) antibodies. Briefly,

(14) Nicotine Exacerbates TAAD Formation Induced by Smooth Muscle-Specific Deletion of the TGF-β Receptor 2Journal of immunology researchJanuary 1, 2021Chun C, Qi X, Wang F, Madrid KB, Saldarriaga LA, Fisch MR, Brantly ML, Upchurch GR Jr, Jiang Z."Rat anti-mouse IgG2a, k","557355, BD Biosciences, San Diego, CA",1 : 250 MMP2,Goat anti-mouse/rat IgG,"AF1488, R&D Systems, Minneapolis, MN",1 : 50 Information of antibodies used in this study.

(15) Temporal and Quantitative Analysis of Aortic Immunopathologies in Elastase-Induced Mouse Abdominal Aortic AneurysmsJournal of immunology researchJanuary 1, 2021Tian K, Xia C, Liu H, Xu B, Wei P, Fu W, Lu M, Li Y, Li Y, Cheng D, et al.angiogenesis, 1 : 200; Cat # 100402; BioLegend), anti-matrix metalloproteinase (MMP) 2 antibody (1 : 200; Cat # AF1488, R&D Systems, Minneapolis, MN), and MMP9 (1 : 200; Cat # AF909, R&D Systems). Secondary antibodies and

(16) Deficiency of peroxiredoxin 2 exacerbates angiotensin II-induced abdominal aortic aneurysmExperimental & molecular medicineSeptember 1, 2020Jeong SJ, Cho MJ, Ko NY, Kim S, Jung IH, Min JK, Lee SH, Park JG, Oh GT.(anti-VEGFR2; 9698; Cell Signaling Technology, Danvers, MA), anti-α-SMA (ab5694; Abcam), anti-MMP2 (AF1488; R&D Systems), anti-MMP9 (AF909; R&D Systems), anti-fibronectin (ab2413; Abcam), anti-collagen IV (ab6586;

(17) Gelatinases Cleave Dentin Sialoprotein IntracellularlyFrontiers in physiologyJanuary 1, 2020Gou X, Xue Y, Zheng H, Yang G, Chen S, Chen Z, Yuan G.purchased from Santa Cruz Biotechnology Inc. (Dallas, TX, United States). Anti-MMP9 (AF909) and Anti-MMP2 (AF1488) antibodies were purchased from R&D SYSTEMS (United States). A monoclonal anti-FURIN (ab183495) and

(18) miR-146b Functions as an Oncogene in Oral Squamous Cell Carcinoma by Targeting HBP1Technology in cancer research & treatmentJanuary 1, 2020Li K, Zhou Z, Li J, Xiang R.β-catenin (1:500) (#9562, Cell Singling technology), Vimentin (1:500) (MAB2105, R&D system), MMP-2(1:500) (AF1488, R&D system), MMP-9(1:500) (AF909, R&D system), and GAPDH (1:1500) (MAB5718, R&D system) overnight.

(19) ATRQβ-001 Vaccine Prevents Experimental Abdominal Aortic AneurysmsJournal of the American Heart AssociationSeptember 17, 2019Zhang H, Liao M, Cao M, Qiu Z, Yan X, Zhou Y, Wu H, Wang Y, Zheng J, Ding J, et al.the following primary antibodies: anti‐CD68 (Abcam, ab31630) for macrophages, anti‐MMP2 (R&D System, AF1488), anti‐MMP9 (R&D System, AF909), anti‐extracellular MMP inducer (EMMPRIN) (Abcam, ab108317), anti‐osteopontin

(20) Modulation of proteoglycan receptor PTPσ enhances MMP-2 activity to promote recovery from multiple sclerosisNature communicationsOctober 8, 2018Luo F, Tran AP, Xin L, Sanapala C, Lang BT, Silver J, Yang Y.(C8035, Sigma, 1:1000), Laminin (L9393, Sigma, 1:1000), GAPDH (AF5718, R and D Systems, 1:1000), MMP-2 (AF1488, R and D Systems, 1:1000), MMP-10 (MAB910, R and D Systems, 1:1000), and β-actin (sc-47778, Santa Cruz,

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MMP-2 Antibody

Mouse/Rat MMP-2 Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (44)

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Mouse/Rat MMP-2 Antibody from R&D Systems, a Bio-Techne Brand

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