Reg4 Antibody AF1379 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemReg4 Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $489.00Supplier Page View Company Product Page
Catalog NumberAF1379
NCBI Gene AliasesGISP, RELP, REG-IV
ApplicationsImmunohistochemistry,Western Blot,Immunohistochemistry-Paraffin
TargetReg4
Conjugate/TagUnconjugated
ReactivityHuman,Mouse
HostGoat
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
Quantity100 ug (also 25 ug)
IsotypeIgG
NCBI Full Gene Nameregenerating family member 4
ClonalityPolyclonal
ImmunogenE. coli-derived recombinant human Reg4, Asp23-Pro158, Accession # Q9BYZ8
ConcentrationLYOPH
PurityAntigen Affinity-purified
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Available conjugates: Unconjugated

Specificity: Detects human Reg4 in direct ELISAs and Western blots. In direct ELISAs, less than 20% cross-reactivity with recombinant mouse (rm) Reg4, rmReg3A, and recombinant rat (rr) Reg3A is observed.

Sizes Available: 100 ug (also 25 ug)

Add to Compare List

R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) REG4 serves as a prognostic biomarker for pancreatic cancer with long-standing diabetes mellitus by modulating chemoresistanceTransl OncolJuly 2, 2026Jae-Il Choi, Hee Jung Park, Hak Park, Yonggeun Cho, Hyo Shik Shin, Young Ik Koh, See Young Lee, Sung Ill Jang, Jae Hee Cho, Hyung Sun Kim, et al.antibodies and secondary antibodies were applied. Antibody details are as follows: REG4 (R&D Systems #AF1379, goat polyclonal, 1:200), CD44 (Biogems #065111-20, rat monoclonal, 1:100), β-catenin (Proteintech #51067-2-AP,

(2) The association of tumor-expressed REG4, SPINK4 and alpha-1 antitrypsin with cancer-associated thrombosis in colorectal cancerJournal of Thrombosis and ThrombolysisDecember 8, 2023Jeroen T. Buijs, Robin van Beijnum, Rayna J. S. Anijs, El Houari Laghmani, Lily Sensuk, Cas Minderhoud, Betül Ünlü, Frederikus A. Klok, Peter J. K. Kuppen, Suzanne C. Cannegieter, et al.antibody. Primary antibodies used were: REG4 antibody (polyclonal Goat IgG, dilution 1:400, R&D systems, AF1379, AB_2178705), SPINK4 antibody (rabbit polyclonal, dilution 1:400; Sigma-Aldrich, HPA007286, AB_1080083)

(3) ARTS mediates apoptosis and regeneration of the intestinal stem cell nicheNature communicationsNovember 2, 2018Koren E, Yosefzon Y, Ankawa R, Soteriou D, Jacob A, Nevelsky A, Ben-Yosef R, Bar-Sela G, Fuchs Y.(Dako; #A0099), XIAP (BD; #610762), cleaved caspase-3 (Cell Signaling; #9661), REG4 (R&D Systems; #AF1379), Chromogranin A (Santa Cruz; #sc-376827), villin (Abcam; ab130751) and BrdU (Santa Cruz; #sc-32323).

(4) Reg4+ deep crypt secretory cells function as epithelial niche for Lgr5+ stem cells in colonProceedings of the National Academy of Sciences of the United States of AmericaSeptember 13, 2016Sasaki N, Sachs N, Wiebrands K, Ellenbroek SI, Fumagalli A, Lyubimova A, Begthel H, van den Born M, van Es JH, Karthaus WR, et al.

(5) REG4 Is Highly Expressed in Mucinous Ovarian Cancer: A Potential Novel Serum BiomarkerPloS oneJanuary 1, 2016Lehtinen L, Vesterkvist P, Roering P, Korpela T, Hattara L, Kaipio K, Mpindi JP, Hynninen J, Auranen A, Davidson B, et al.staining. Membranes were blocked with 5% milk-TBST and probed with polyclonal REG4 antibody (1:1000, AF1379, R&D Systems, Minneapolis, MN) and HRP-conjugated anti-goat secondary antibody (1:5000, Dako, Glostrup,

(6) REG4 acts as a mitogenic, motility and pro-invasive factor for colon cancer cellsInternational journal of oncologyMarch 1, 2010Rafa L, Dessein AF, Devisme L, Buob D, Truant S, Porchet N, Huet G, Buisine MP, Lesuffleur T.

(7) Reg IV is a serum biomarker for gastric cancer patients and predicts response to 5-fluorouracil-based chemotherapyOncogeneJune 28, 2007Mitani Y, Oue N, Matsumura S, Yoshida K, Noguchi T, Ito M, Tanaka S, Kuniyasu H, Kamata N, Yasui W.

(8) "IL2RG, identified as overexpressed by RNA-seq profiling of pancreatic intraepithelial neoplasia, mediates pancreatic cancer growth"OncotargetJanuary 1, 0001"Ayars M, O'Sullivan E, Macgregor-Das A, Shindo K, Kim H, Borges M, Yu J, Hruban RH, Goggins M."Santa Cruz Biotechnology (CA, USA); Kcnj15 (NBP1-83091, 1:100 dilution) from Novus Biologicals (CA, USA); and Reg4 (AF1379) from R&D Systems (MN, USA). For Kcnj15, Gata4, Reg4, Muc4, and Fscn1, TMA cores were scored based on

(9) RNA sequencing of sessile serrated colon polyps identifies differentially expressed genes and immunohistochemical markersPloS oneJanuary 1, 0001"Delker DA, McGettigan BM, Kanth P, Pop S, Neklason DW, Bronner MP, Burt RW, Hagedorn CH."were purchased from R&D Systems (anti-VSIG1, cat. #AF4818; anti-CTSE, cat #AF1294; anti-REG4, cat.#AF1379), Sigma-Aldrich (anti-MUC17, cat #HPA031634), ProteinTech (anti-TFF2, cat #12681-1-AP. Four-micron sections

(10) Activation of REG family proteins in colitisScandinavian journal of gastroenterologyJanuary 1, 0001"Granlund Av, Beisvag V, Torp SH, Flatberg A, Kleveland PM, Ostvik AE, Waldum HL, Sandvik AK."RD181078100, BioVendor, Midrice, Czech Republic, dilution 1:500), REGIV – polyclonal goat antibody (Cat No AF1379, R&D Systems, Minneapolis, MN, USA, dilution 1:400), DEFA6 – polyclonal rabbit antibody (Cat no HPA019462,

(11) REG gene expression in inflamed and healthy colon mucosa explored by in situ hybridisationCell and tissue researchJanuary 1, 0001"van Beelen Granlund A, Østvik AE, Brenna Ø, Torp SH, Gustafsson BI, Sandvik AK."REG1A (cat. no. RD181078100, BioVendor, Midrice, Czech Republic; dilution 1:500), REG4 (REGIV, cat. no. AF1379, R&D Systems, Minneapolis, Minn., USA; dilution 1:400), REG3A (cat. no. AB134209, Abcam, Cambridge,

Be the First to Write a Review!

Reg4 Antibody

Reg4 Antibody

Reg4 Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (11)

Reviews

Reg4 Antibody from R&D Systems, a Bio-Techne Brand

About Biocompare

Advertise with Us

Specialized Search Tools

Site Map