Human PDGF R alpha Antibody AF-307-NA from R&D Systems, a Bio-Techne Brand

Product Specs
ItemHuman PDGF R alpha Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $519.00Supplier Page View Company Product Page
Catalog NumberAF-307-NA
NCBI Gene AliasesCD140A, PDGFR-2, PDGFR2
ApplicationsImmunodepletion,Flow Cytometry,Immunohistochemistry,Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Neutralization,Immunocytochemistry
HostGoat
Quantity100 ug (also 25 ug)
ReactivityHuman,Mouse,Rabbit,Rat
TargetPDGF R alpha
Conjugate/TagUnconjugated
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
IsotypeIgG
NCBI Full Gene Nameplatelet derived growth factor receptor alpha
ClonalityPolyclonal
ImmunogenS. frugiperda insect ovarian cell line Sf 21-derived recombinant human PDGF R alpha, Gln24-Glu524, Accession # P16234
ConcentrationLYOPH
PurityAntigen Affinity-purified
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Unconjugated

Questions and Answers

Can this antibody be used to study PDGFR-alpha in human tissues?

Yes, the PDGF R alpha antibody has been shown to effectively detect human PDGF R alpha in various applications, including immunofluorescence, as demonstrated in studies such as and .

Is this antibody suitable for use in oligodendrocyte research?

The PDGF R alpha antibody has been utilized in research focused on oligodendrocyte development and function, as indicated in studies like . It was used to investigate the role of PDGFR-alpha in oligodendrocyte maturation and signaling pathways.

What experimental techniques can I use this antibody with?

This antibody is versatile and can be used in several applications, including Western blotting, immunocytochemistry, immunohistochemistry, and flow cytometry, as noted in the product specifications and supported by its use in various studies.

How specific is this antibody for PDGFR-alpha?

The PDGF R alpha antibody exhibits high specificity, with less than 2% cross-reactivity with recombinant mouse PDGF R alpha and other related receptors, making it a reliable choice for detecting PDGFR-alpha in human samples, as evidenced by its application in multiple research articles.

R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Robust immune cell infiltration and macrophage senescence occur within a week of recovery after limb immobilization in older adult skeletal muscleThe Journal of PhysiologyMarch 27, 2026Chad M. Skiles, Zachary J. Fennel, Paul‐Emile Bourrant, Elena M. Yee, Robert J. Castro, Hannah A. Zabriskie, Melina Itinose, Mark A. Supiano, Ryan M. O'Connell, Micah J. Drummondno. 17372‐87‐1; Sigma‐Aldrich); CD45+ (catalog. no. ab528428; Abcam)]; FAPs (PDGFRα+; catalog. no. AF‐307‐NA; R&D Systems, Minnneapolis, MN, USA); cellular senescence (SA‐β‐galactosidase+; catalog. no. B4252‐100MG;

(2) Rete ridges form via evolutionarily distinct mechanisms in mammalian skinNatureFebruary 4, 2026Sean M. Thompson, Violet S. Yaple, Gabriella H. Searle, Quan M. Phan, Jasson Makkar, Xiangzheng Cheng, Ruiqi Liu, Anna Pulawska-Czub, Corin Yanke, Natalie M. Williams, et al.ab5694, clone proprietary, lot no. 1038192-2), human-PDGFRA goat (1:250, R&D Systems, catalogue no. AF307NA, clone P16234, lot no. VG0721111) in pig and marmoset samples, mouse-PDGFRA goat (1:250, R&D Systems,

(3) A Human Model of Oligodendrocyte Development Shows MCL-1 Influences Oligodendrocyte MorphogenesisGliaDecember 19, 2025Melanie Gil, Marina R. Hanna, Vivian Gamanumber OLIG2,Rabbit,IF—1:500,Millipore,AB9610 OLIG2,Mouse,IF—1:500 WB—1:1000,Millipore,MABN50 PDGFRα,Goat,IF—1:100,R&D Systems,AF‐307‐NA MBP,Rat,IF—1:100,Millipore,MAB386 Mitochondria,Rabbit,IF—1:200,Abcam,ab92824 ISL1/2,Mouse,IF—1:200,DSHB,39.4D5 NF‐200,Mouse,IF—1:200,Millipore,N5389 Beta‐III‐Tubulin,Rabbit,IF—1:200,Abcam,ab18207 MOG,Goat,IF—1:500,R&D Systems

(4) Mirabegron treatment reduces myofibroblasts and CXCR2 expression in adipose tissue in obesityMol MedOctober 14, 2025Brian S. Finlin, Hasiyet Memetimin, Philip M. Westgate, Jin Chen, Esther E. Dupont-Versteegden, Philip A. Kernafter all blocking steps, the sections were incubated overnight with goat anti-PDGFRA (R&D system, AF-307-NA), washed, and incubated with biotinylated donkey anti-goat IgG (Jackson ImmunoResearch, catalog #705-065-147)

(5) Complementing muscle regeneration—fibro-adipogenic progenitor and macrophage-mediated repair of elderly human skeletal muscleNat CommunJune 5, 2025Jonas Brorson, Lin Lin, Jakob Wang, Amanda Bæk, Tine Borum Billeskov, Frederik Forsberg Thybo, Jesper Just, János Haskó, Christen Ravn, Rehne L. Hansen, et al.1:100, cat. no.: M0718, Dako Norden, Glostrup Denmark), PDGFR-α (goat anti human, 1:300, cat. no.: AF-307-NA; RRID: AB_354459, R&D Systems, Bio-Techne), Complement Factor Bb (mouse anti-human, 1:100, cat. no.:

(6) Gastrodin promotes CNS myelinogenesis and alleviates demyelinating injury by activating the PI3K/AKT/mTOR signalingActa pharmacologica SinicaJune 1, 2025Shi XY, He YX, Ge MY, Liu P, Zheng P, Li ZH.

(7) Cytomegalovirus host receptor expression in the human fetal inner earPLoS OneMarch 31, 2025Lucia C. M. Grijpink, Wouter H. van der Valk, Edward S. A. van Beelen, John C. M. J. de Groot, Heiko Locher, Ann C. T. M. Vossen,Novus Biologicals,NBP1-30151,AB_1987285,1:200 MYO7A,Mouse,DSHB,138-1-s,AB_2282417,3:10 NRP2,Mouse,Santa Cruz Biotechnology,sc-13117,AB_628044,1:200 PDGFRA,Goat,Novus Biologicals,AF-307-NA,AB_354459,1:100 PECAM1,Rabbit,Novus Biologicals,NB100-2284,AB_10002513,1:100 TUBB3,Mouse,Abcam,ab7751,AB_306045,1:500 TUBB3,Rabbit,Abcam,ab18207,AB_444319,1:200 ,Isotype

(8) The Efficacy of Blood Flow Restriction Training to Improve Quadriceps Muscle Function after Anterior Cruciate Ligament ReconstructionMedicine & Science in Sports & ExerciseFebruary 1, 2025LAUREN N. ERICKSON, MEREDITH K. OWEN, KELSEY R. CASADONTE, TEREZA JANATOVA, KATHRYN LUCAS, KYLIE SPENCER, BENJAMIN D. BRIGHTWELL, MEGAN C. GRAHAM, MCKENZIE S. WHITE, NICHOLAS T. THOMAS, et al.staining of FAPs, slides were fixed in 4% paraformaldehyde and incubated overnight in anti-PDGFRα (#AF-307-NA; R&D Systems, Minneapolis, MN) and AF488-conjugated WGA (#W11261; ThermoFisher). The following day,

(9) Compensatory changes after spinal cord injury in a remyelination deficient mouse modelJournal of NeurochemistryJanuary 1, 2025S. B. Manesh, B. R. Kondiles, S. Wheeler, J. Liu, L. Zhang, C. Chernoff, G. J. Duncan, M. S. Ramer, W. Tetzlaffthe following antigens: GFP (1:4000, Abcam, ab13970, RRID:AB_300798), PDGFRa (1:200, R and D Systems, AF‐307‐NA, RRID:AB_354459), NF200 (1:1000, Sigma, N0142, RRID:AB_477257), Nav1.2 (1:200, Alamone, ASC‐002, RRID:AB_2040005),

(10) MCL-1 regulates cellular transitions during oligodendrocyte developmentbioRxivDecember 23, 2024Melanie Gil, Marina R Hanna, Vivian Gama1:500,Millipore,AB9610 OLIG2,Mouse,IF - 1:500 WB - 1:1000,Millipore,MABN50 PDGFRα,Goat,IF - 1:100,R&D Systems,AF-307-NA MBP,Rat,IF - 1:100,Millipore,MAB386 Mitochondria,Rabbit,IF - 1:200,Abcam,ab92824 ISL1/2,Mouse,IF

(11) SMOC1 colocalizes with Alzheimer's disease neuropathology and delays Aβ aggregationActa neuropathologicaNovember 25, 2024Balcomb K, Johnston C, Kavanagh T, Leitner D, Schneider J, Halliday G, Wisniewski T, Sunde M, Drummond E.

(12) 3D model for human glia conversion into subtype-specific neurons, including dopamine neuronsCell Reports MethodsSeptember 16, 2024Jessica Giacomoni, Andreas Bruzelius, Mette Habekost, Janko Kajtez, Daniella Rylander Ottosson, Alessandro Fiorenzano, Petter Storm, Malin ParmarAB_10561973 PDGFRα,Cell Signaling Technology,Cat# 5241S; RRID: AB_10692773 PDGFRα,R&D Systems,Cat# AF-307-NA; RRID: AB_354459 PE anti-human CD140a,BD Biosciences,Cat# 556002; RRID: AB_396286 SOX10,R&D Systems,Cat#

(13) A human autoimmune organoid model reveals IL-7 function in coeliac diseaseNatureAugust 1, 2024Santos AJM, van Unen V, Lin Z, Chirieleison SM, Ha N, Batish A, Chan JE, Cedano J, Zhang ET, Mu Q, et al.anti-CK-19 (R&D systems, AF3506, 1:400), anti-CD3 (BioLegend, 300431, 1:250), anti-PDGFRA (R&D Systems, AF-307-NA, 1:250), anti-ECAD (BD, 610181, 1:400), anti-PGP9.5 (Genetex, GTX109637, 1:250), anti-CD45 (Cell Signaling,

(14) Patterning and folding of intestinal villi by active mesenchymal dewettingCellJune 6, 2024Huycke TR, Häkkinen TJ, Miyazaki H, Srivastava V, Barruet E, McGinnis CS, Kalantari A, Cornwall-Scoones J, Vaka D, Zhu Q, et al.anti-PDGFRA (mouse),R&D Systems,Cat#AF1062; RRID:AB_2236897 Goat anti-PDGFRA (human),R&D Systems,Cat#AF-307-NA; RRID:AB_354459 Rabbit anti-MYH9,BioLegend,Cat#909801; RRID:AB_2734686 Rabbit anti-MYH10,BioLegend,Cat#909901;

(15) Harnessing developmental dynamics of spinal cord extracellular matrix improves regenerative potential of spinal cord organoidsCell stem cellMay 2, 2024Sun Z, Chen Z, Yin M, Wu X, Guo B, Cheng X, Quan R, Sun Y, Zhang Q, Fan Y, et al.

(16) Early Postnatal Expression of Tgfβ-1 and Fgf-2 Correlates With Regenerative Functions of Unrestricted Somatic Stem Cell Infusion After Rabbit GMH-IVHStem Cells Translational MedicineDecember 18, 2023Dina A Finkel, Ana Malfa, Yanling Liao, Deepti Purohit, Furong Hu, Davud Sulaymankhil, Sai Abhishek Abhishek Narra, Karen Hussein, Selvakumar Subbian, Mitchell S Cairo, et al.performed, as we previously described.38,39 The primary antibodies used in the study: PDGFRα (catalog # AF307 NA, R&D Systems, Minneapolis), Olig2+ (catalog # AF2418, R&D Systems, Minneapolis), Ki67+ (catalog # M724029,

(17) Patterning and folding of intestinal villi by active mesenchymal dewettingbioRxiv : the preprint server for biologyAugust 15, 2023Huycke TR, Miyazaki H, Häkkinen TJ, Srivastava V, Barruet E, McGinnis CS, Kalantari A, Cornwall-Scoones J, Vaka D, Zhu Q, et al.,Cell Signaling Technology,#3195 CDH1 (1:300),BD Bioscience,#610182 PDGFRA (1:500),R&D Systems,#AF1062 PDGFRA (1:300),R&D Systems,#AF-307-NA MYH9 (1:100),BioLegend,#909901 MYH10 (1:100),BioLegend,#909802 MYH14 (1:100),Cell Signaling Technology,#8189s pMLC

(18) Metformin promotes Schwann cell remyelination, preserves neural tissue and improves functional recovery after spinal cord injuryNeuropeptidesAugust 1, 2023Huang Z, Lin J, Jiang H, Lin W, Huang Z, Chen J, Xiao W, Lin Q, Wang J, Wen S, et al.

(19) High-throughput screening for myelination promoting compounds using human stem cell-derived oligodendrocyte progenitor cellsiScienceMarch 17, 2023Li W, Berlinicke C, Huang Y, Giera S, McGrath AG, Fang W, Chen C, Takaesu F, Chang X, Duan Y, et al.

(20) Non-myogenic mesenchymal cells contribute to muscle degeneration in facioscapulohumeral muscular dystrophy patientsCell death & diseaseSeptember 16, 2022Di Pietro L, Giacalone F, Ragozzino E, Saccone V, Tiberio F, De Bardi M, Picozza M, Borsellino G, Lattanzi W, Guadagni E, et al.USA) anti-PDGFRα (1:500, #3174, Cell Signalling Technology, Danvers, MA, USA) and anti-PDGFRα (1:100, #AF-307-NA, R&D systems). The following secondary antibodies were used and incubated for 45 min at RT in PBS with

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7/3/2017Good PDGFR Antibody for Immunohistochemistry Juwen DuBoisWe wanted to compare the amount PDGFR positive cells in the spinal cords of 2 different mouse strains.

PDGF R alpha Antibody

PDGF R alpha Antibody

PDGF R alpha Antibody

PDGF R alpha Antibody

PDGF R alpha Antibody

Human PDGF R alpha Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

Questions and Answers

R&D Systems, a Bio-Techne Brand

Citations (77)

Reviews

Human PDGF R alpha Antibody from R&D Systems, a Bio-Techne Brand

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