CCL2/JE/MCP-1 Antibody AF-279-NA from R&D Systems, a Bio-Techne Brand

Product Specs
ItemCCL2/JE/MCP-1 Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $519.00Supplier Page View Company Product Page
Catalog NumberAF-279-NA
NCBI Gene AliasesMCP1, MCAF, HSMCR30, HC11, SMC-CF, GDCF-2, SCYA2, MCP-1
ApplicationsBioassay,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Neutralization,Immunocytochemistry,ELISA Detection
Quantity100 ug (also 25 ug)
IsotypeIgG
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
ReactivityHuman,Primate - Macaca mulatta (Rhesus Macaque),Rabbit,Rat
Conjugate/TagUnconjugated
TargetCCL2/JE/MCP-1
HostGoat
NCBI Full Gene NameC-C motif chemokine ligand 2
ClonalityPolyclonal
ImmunogenE. coli-derived recombinant human CCL2/JE/MCP-1, Gln24-Thr99, Accession # P13500
ConcentrationLYOPH
PurityAntigen Affinity-purified
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Available conjugates: Unconjugated

Specificity: Detects human CCL2/JE/MCP-1 in direct ELISAs and Western blots.

Sizes Available: 100 ug (also 25 ug)

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Sigma-1 receptor regulates HIV-1 and methamphetamine-induced endothelial/pericyte barrier impairment via strain-specific inflammatory responses and mitochondrial dysregulationJournal of NeuroinflammationMarch 6, 2026Nikolai Fattakhov, Silvia Torices, Sarah Becker, Joelle-Ann Joseph, Sarah Schmidlin, Alex Ngo, Adesuwa Okoro, Oandy Naranjo, Michal ToborekCCL2, cultures were incubated with an anti-human CCL2 neutralizing antibody (8 µg/mL; R&D Systems, Cat# AF-279-NA) or with normal goat IgG as a control (R&D Systems, Cat# AB-108-C). Cell viability assay HBVP viability

(2) Cancer Manipulates Adjacent Adipose Tissue to Exploit Fatty Acids via HIF‐1α/CCL2/PPARα Axis: A Metabolic Circuit to Support Tumor ProgressionAdvanced ScienceJanuary 1, 2026Jeong‐Eun Yun, Jieun Seo, Jiwon Koh, Seock‐Ah Im, Ki Yong Hong, Yeseon Son, Do‐Won Jeong, Junji Fukuda, Jong‐Wan Park, Yang‐Sook Chuntreated at a concentration of 10 or 20 ng mL−1. For neutralizing CCL2, human neutralizing antibody‐CCL2 (#AF‐279‐NA, R&D systems) was treated to human cell lines at a concentration of 1 µg mL−1 and mouse neutralizing

(3) Post-acute sequelae of SARS-CoV-2 cardiovascular symptoms are associated with trace-level cytokines that affect cardiomyocyte functionNature microbiologyDecember 1, 2024Sinclair JE, Vedelago C, Ryan FJ, Carney M, Redd MA, Lynn MA, Grubor-Bauk B, Cao Y, Henders AK, Chew KY, et al.

(4) CCL2-mediated endothelial injury drives cardiac dysfunction in long COVIDNature Cardiovascular ResearchOctober 14, 2024Dilip Thomas, Chikage Noishiki, Sadhana Gaddam, David Wu, Amit Manhas, Yu Liu, Dipti Tripathi, Nimish Kathale, Shaunak S. Adkar, Jaishree Garhyan, et al.BSA and incubated overnight with the following antibody dilutions: human CCL2 antibody (R&D systems, AF-279-NA, 1:1000), mouse CCL2 antibody (R&D systems, AF-479-NA, 1:1000), human or mouse pRyR2 antibody (Thermo Fisher Scientific

(5) Tumor-associated tissue eosinophilia promotes angiogenesis and metastasis in head and neck squamous cell carcinomaNeoplasia (New York, N.Y.)January 1, 2023Lee TL, Chen TH, Kuo YJ, Lan HY, Yang MH, Chu PY.the membrane were fixed in 4% formaldehyde and stained with Coomassie Brilliant Blue (catalogue no. AF-279-NA, R&D Systems, Minneapolis,MN). The number of migrated cells was quantified under a 40X objective lens

(6) MCP-1 targeting: Shutting off an engine for tumor developmentOncology lettersJanuary 1, 2022Wang L, Lan J, Tang J, Luo N.,R&D systems,2004,Human glioblastoma multiforme (91); human breast cancer cell line MCF10CA1d (CA1d) (78), AF-279-NA,Human MCP-1 antibody,R&D systems,2004,Human lung cancer (92), CNTO888/carlumab,Human MCP-1 antibody,Centocor

(7) Teneligliptin prevents doxorubicin-induced inflammation and apoptosis in H9c2 cellsArchives of biochemistry and biophysicsApril 15, 2020Peng W, Rao D, Zhang M, Shi Y, Wu J, Nie G, Xia Q.

(8) HIV-1 Tat promotes astrocytic release of CCL2 through MMP/PAR-1 signalingGliaSeptember 1, 2019Bozzelli PL, Yin T, Avdoshina V, Mocchetti I, Conant KE, Maguire-Zeiss KA.blocking buffer: mouse anti-MMP-13 (ThermoFisher, MA5–14238, 1:100); goat anti-CCL2/MCP-1 (R&D Systems, AF-279-NA, 1:1000); Rabbit anti-Thrombin R (PAR-1; Santa Cruz Biotechnology, SC-5605, 1:1000); mouse anti-GAPDH

(9) Interleukin-17 induces angiogenesis in vitro via CXCL8 and CCL2 in retinal pigment epitheliumMolecular medicine reportsMarch 1, 2018Chen Y, Zhong M, Yuan G, Peng H.cat. no. AF‑208‑NA) and/or 0.2 µg/ml neutralizing antibody against CCL2 (R&D Systems, Inc. cat. no. AF‑279‑NA), for 10 min at room temperature. Images were taken at 0, 4, 8 and 12 h with a fluorescence microscope

(10) Epitope Mapping of Mono- and Polyclonal Antibodies by Screening Phage-displayed Random Peptide LibrariesActa chimica SlovenicaDecember 1, 2016Molek P, Bratkovič T.Systems Abcam Abcam R&D Systems Catalogue No. sc-10368 (in-house affinity purified) MAB398 AF-398 ab9669 ab18678 AF-279-NA Clone polyclonal Host/IgG isotype goat 44802 polyclonal polyclonal S101 polyclonal mouse/IgG1 goat rabbit mouse/IgG1 goat Molek

(11) Characterization of Innate Immunity in an Extended Whole Blood Model of Human Islet AllotransplantationCell transplantationJanuary 1, 2016Hårdstedt M, Lindblom S, Karlsson-Parra A, Nilsson B, Korsgren O.MAB208; detection: AF-208-NA; R&D Systems, Minneapolis, MN, USA), MCP-1 (capture: MAB279; detection: AF-279-NA; R&D Systems), and IL-6 (capture: 554543; BD Pharmingen; detection: MAB206; R&D Systems). A standard

(12) Multivariate analysis of traumatic brain injury: development of an assessment scoreFrontiers in neurologyJanuary 1, 2015Buonora JE, Yarnell AM, Lazarus RC, Mousseau M, Latour LL, Rizoli SB, Baker AJ, Rhind SG, Diaz-Arrastia R, Mueller GP.# 2488D005 345996 279-MD-010 1950-M5 H00002026-P01 S6677 Vendor R&D DAKO R&D R&D R&D Genway Catalog # MAB648 Z0334 AF-279-NA AF1950 AF5169 18-272-198528 R&D: R&D Systems Inc., Minneapolis, MN, USA. Sigma: Sigma Aldrich, St

(13) Autophagy facilitates TLR4- and TLR3-triggered migration and invasion of lung cancer cells through the promotion of TRAF6 ubiquitinationAutophagyFebruary 1, 2014Zhan Z, Xie X, Cao H, Zhou X, Zhang XD, Fan H, Liu Z.of DMSO in culture medium is < 0.2% volume. Neutralizing antibodies against IL6 (AB-206-NA), CCL2 (AF-279-NA) and CCL20 (MAB360) were from R&D Systems. Antibodies were obtained from the following sources: TLR4 (ab13867),

(14) Neuroblastoma-derived TGF-β1 modulates the chemokine receptor repertoire of human resting NK cellsJournal of immunology (Baltimore, Md. : 1950)May 15, 2013Castriconi R, Dondero A, Bellora F, Moretta L, Castellano A, Locatelli F, Corrias MV, Moretta A, Bottino C.

(15) Fractalkine is a novel human adipochemokine associated with type 2 diabetesDiabetesMay 1, 2011Shah R, Hinkle CC, Ferguson JF, Mehta NN, Li M, Qu L, Lu Y, Putt ME, Ahima RS, Reilly MP.

(16) Irritant-induced migration of Langerhans cells coincides with an IL-10-dependent switch to a macrophage-like phenotypeThe Journal of investigative dermatologyFebruary 1, 2011Ouwehand K, Oosterhoff D, Breetveld M, Scheper RJ, de Gruijl TD, Gibbs S.

(17) Stromal MCP-1 in mammary tumors induces tumor-associated macrophage infiltration and contributes to tumor progressionInternational journal of cancerSeptember 15, 2009Fujimoto H, Sangai T, Ishii G, Ikehara A, Nagashima T, Miyazaki M, Ochiai A.

(18) Interleukin-18 predicts atherosclerosis progression in SIV-infected and uninfected rhesus monkeys (Macaca mulatta) on a high-fat/high-cholesterol dietLaboratory investigation; a journal of technical methods and pathologyJune 1, 2009Yearley JH, Xia D, Pearson CB, Carville A, Shannon RP, Mansfield KG.

(19) A potential role of thymic stromal lymphopoietin in the recruitment of macrophages to mouse intervertebral disc cells via monocyte chemotactic protein 1 induction: implications for herniated discsArthritis and rheumatismNovember 1, 2008Ohba T, Haro H, Ando T, Koyama K, Hatsushika K, Suenaga F, Ohnuma Y, Nakamura Y, Katoh R, Ogawa H, et al.

(20) Expanded-polyglutamine huntingtin protein suppresses the secretion and production of a chemokine (CCL5/RANTES) by astrocytesThe Journal of neuroscience : the official journal of the Society for NeuroscienceMarch 26, 2008Chou SY, Weng JY, Lai HL, Liao F, Sun SH, Tu PH, Dickson DW, Chern Y.

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CCL2/JE/MCP-1 Antibody

CCL2/JE/MCP-1 Antibody

CCL2/JE/MCP-1 Antibody

CCL2/JE/MCP-1 Antibody

CCL2/JE/MCP-1 Antibody

CCL2/JE/MCP-1 Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

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CCL2/JE/MCP-1 Antibody from R&D Systems, a Bio-Techne Brand

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