FANCD2 Antibody (FI-17)

Product Specs
ItemFANCD2 Antibody (FI-17) - BSA Free
CompanyNovus Biologicals, a Bio-Techne Brand
Price $429.00Supplier Page View Company Product Page
Catalog NumberNB100-316
ImmunogenThis FANCD2 Antibody (FI-17) was developed against human FANCD2 fusion protein [Swiss-Prot: Q9BXW9]
NCBI Gene AliasesFAD2, FACD, FANCD, FA4, FAD, FA-D2
TargetFANCD2
HostMouse
Quantity0.1 ml (also 0.025 ml)
Conjugate/TagUnconjugated
ReactivityHuman,Mouse
ApplicationsImmunoprecipitation,Western Blot,Simple Western,Chromatin Immunoprecipitation (ChIP),Immunocytochemistry/ Immunofluorescence
FormatAscites
CloneFI-17
ClonalityMonoclonal
NCBI Full Gene NameFA complementation group D2
PurityUnpurified
Research AreaBreast Cancer, Cancer, DNA Double Strand Break Repair, DNA Repair, Epigenetics, Genes Sensitive to DNA Damaging Agents
IsotypeIgG1
Molecular Weight164.1 kDa
Antibody TypePrimary Antibodies
StorageAliquot and store at -20C or -80C. Avoid freeze-thaw cycles

Specifications/Features

Available conjugates: Available conjugates: Unconjugated

Sizes Available: 0.1 ml (also 0.025 ml)

Add to Compare List

Novus Biologicals, a Bio-Techne Brand

United States: 10771 E Easter Ave

Centennial, Colorado 80112

United States

Phone:
303-730-1950
888-506-6887

Email: novus@novusbio.com

Company Profile

Website: https://www.novusbio.com

(1) TSN Disrupts Fanconi Anemia Pathway Activation Through JAK/STAT1-Mediated Transcriptional Repression of FA Core Subunits in Bladder CancerDose ResponseDecember 2, 2025Wenchao Zhao, Zhiyuan Xie, Liang Zhu, Wenqi Liovernight at 4°C with primary antibodies against FANCI (20789-1-AP, Proteintech, China, 1: 2000), FANCD2 (NB100-316, Novus Biologicals, USA, 1: 2000), β-Actin (AC026, ABclonal, China, 1: 2000), FANCL (A6812, ABclonal,

(2) Oxidative stress/damage induces multimerization and interaction of Fanconi anemia proteinsThe Journal of biological chemistryJanuary 1, 0001"Park SJ, Ciccone SL, Beck BD, Hwang B, Freie B, Clapp DW, Lee SH."

(3) HSF2BP negatively regulates homologous recombination in DNA interstrand crosslink repairNucleic acids researchJanuary 1, 0001"Sato K, Brandsma I, van Rossum-Fikkert SE, Verkaik N, Oostra AB, Dorsman JC, van Gent DC, Knipscheer P, Kanaar R, Zelensky AN."

(4) Fanconi anemia D2 protein is an apoptotic target mediated by caspasesJournal of cellular biochemistryJanuary 1, 0001"Park SJ, Beck BD, Saadatzadeh MR, Haneline LS, Clapp DW, Lee SH."

(5) XPF-ERCC1 participates in the Fanconi anemia pathway of cross-link repairMolecular and cellular biologyJanuary 1, 0001"Bhagwat N, Olsen AL, Wang AT, Hanada K, Stuckert P, Kanaar R, D'Andrea A, Niedernhofer LJ, McHugh PJ."

(6) Utility of DNA repair protein foci for the detection of putative BRCA1 pathway defects in breast cancer biopsiesMolecular cancer research : MCRJanuary 1, 0001"Willers H, Taghian AG, Luo CM, Treszezamsky A, Sgroi DC, Powell SN."

(7) HES1 is a novel interactor of the Fanconi anemia core complexBloodJanuary 1, 0001"Tremblay CS, Huang FF, Habi O, Huard CC, Godin C, Lévesque G, Carreau M."

(8) Fanconi anemia signaling network regulates the spindle assembly checkpointThe Journal of clinical investigationJanuary 1, 0001"Nalepa G, Enzor R, Sun Z, Marchal C, Park SJ, Yang Y, Tedeschi L, Kelich S, Hanenberg H, Clapp DW."

(9) Involvement of p29 in DNA damage responses and Fanconi anemia pathwayCarcinogenesisJanuary 1, 0001"Chu PC, Wang TY, Lu YT, Chou CK, Yang YC, Chang MS."

(10) Overnight transduction with foamyviral vectors restores the long-term repopulating activity of Fancc-/- stem cellsBloodJanuary 1, 0001"Si Y, Pulliam AC, Linka Y, Ciccone S, Leurs C, Yuan J, Eckermann O, Fruehauf S, Mooney S, Hanenberg H, et al."

(11) The antitumor agent doxorubicin binds to Fanconi anemia group F proteinBioorganic & medicinal chemistryJanuary 1, 0001"Kusayanagi T, Tsukuda S, Shimura S, Manita D, Iwakiri K, Kamisuki S, Takakusagi Y, Takeuchi T, Kuramochi K, Nakazaki A, et al."

(12) Human Mus81 and FANCB independently contribute to repair of DNA damage during replicationGenes to cells : devoted to molecular & cellular mechanismsJanuary 1, 0001"Nomura Y, Adachi N, Koyama H."

(13) FANCD2 maintains replication fork stability during misincorporation of the DNA demethylation products 5-hydroxymethyl-2'-deoxycytidine and 5-hydroxymethyl-2'-deoxyuridineCell death & diseaseJanuary 1, 0001"Peña-Gómez MJ, Moreno-Gordillo P, Narmontė M, García-Calderón CB, Rukšėnaitė A, Klimašauskas S, Rosado IV."antibodies used were against ser139-H2AX (Millipore, 05-636), PAR (Millipore, MABE1016), FANCD2 (Novus, NB100-316), ser345-CHK1 (Cell Signaling 2348), CHK1 (sc-8408), ERCC1 (sc-8408), PCNA (sc-56), Lamin A/C (sc-376248),

(14) ERCC1-XPF targeting to psoralen-DNA crosslinks depends on XPA and FANCD2Cellular and molecular life sciences : CMLSJanuary 1, 0001"Sabatella M, Pines A, Slyskova J, Vermeulen W, Lans H."(sc-853, Santa Cruz Biotechnology), anti-SNF2H (ab3749, Abcam), anti-Tubulin (T6074, Sigma), anti-FANCD2 (nb100-316, Novus Biologicals), anti-GFP (ab290, Abcam), anti-SLX4 (NBP1-28680, Novus Biologicals), anti-ERCC1

(15) RAD18 opposes transcription-associated genome instability through FANCD2 recruitmentPLoS geneticsJanuary 1, 0001"Wells JP, Chang EY, Dinatto L, White J, Ryall S, Stirling PC."(Lys164) (NE Biolabs 13439S) (1:1000), anti-GAPDH (Thermofisher MA5-15738) (1:2000), anti-FANCD2 (Novus, NB100-316), anti-Vinculin (Santa Cruz, sc-25336), anti-H3 (Cell Signaling, 9715). Secondary antibodies were conjugated

(16) Base and nucleotide excision repair facilitate resolution of platinum drugs-induced transcription blockageNucleic acids researchJanuary 1, 0001"Slyskova J, Sabatella M, Ribeiro-Silva C, Stok C, Theil AF, Vermeulen W, Lans H."used were against CSB (E-18, 1:250, Santa Cruz, sc-10459), FANCD2 (FI-17, 1:1000, Novus Biologicals, nb100-316), XPA (FL-273, 1:100, Santa Cruz, sc-853), γH2AX (JBW301, 1:1000, Millipore, 05-636). Secondary antibodies

Be the First to Write a Review!