GPER/GPR30 Antibody

Product Specs
ItemGPER/GPR30 Antibody - BSA Free
CompanyNovus Biologicals, a Bio-Techne Brand
Price $399.00Supplier Page View Company Product Page
Catalog NumberNLS1183
ImmunogenSynthetic 16 amino acid peptide from 1st cytoplasmic domain of human GPER/GPR30
Concentration1.0 mg/ml
TargetGPER/GPR30
Quantity0.05 ml
Conjugate/TagUnconjugated
ReactivityHuman,Mouse
FormatPBS
ApplicationsIF/IHC,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunocytochemistry/ Immunofluorescence
HostRabbit
ClonalityPolyclonal
PurityImmunogen affinity purified
Research AreaGPCR, Neuroscience
IsotypeIgG
Antibody TypePrimary Antibodies
StorageKeep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles
NCBI Gene AliasesGPER, CEPR, mER, LERGU, LERGU2, FEG-1, LyGPR, GPCR-Br, GPR30, CMKRL2, DRY12
NCBI Full Gene NameG protein-coupled estrogen receptor 1

Specifications/Features

Available conjugates: Available conjugates: Unconjugated

Specificity: Human GPR30. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Sizes Available: 0.05 ml

Add to Compare List

Questions and Answers

Can this antibody be used for studying GPER expression in melanoma tissues?

Yes, the GPER/GPR30 Antibody has been utilized in immunohistochemistry to assess GPER expression in various melanocytic lesions, including melanoma. In a study, it was shown that GPER expression was higher in dysplastic nevi compared to melanoma, indicating its potential relevance in melanoma research ().

What is the recommended dilution for using this antibody in immunohistochemistry?

The GPER/GPR30 Antibody has been used at a dilution of 1:50 in immunohistochemistry, as demonstrated in a study assessing estrogen receptor expression in melanocytic lesions ().

Is this antibody reactive with both human and mouse samples?

Yes, the GPER/GPR30 Antibody is reactive with both human (Homo sapiens) and mouse (Mus musculus) samples, making it suitable for comparative studies across these species.

What type of research applications is this antibody suitable for?

The GPER/GPR30 Antibody is suitable for various applications, including Western blotting, immunocytochemistry, immunofluorescence, and immunohistochemistry, particularly in studies related to G protein-coupled receptors and their role in cell biology and neuroscience.

Novus Biologicals, a Bio-Techne Brand

United States: 10771 E Easter Ave

Centennial, Colorado 80112

United States

Phone:
303-730-1950
888-506-6887

Email: novus@novusbio.com

Company Profile

Website: https://www.novusbio.com

(1) 17Beta-estradiol at low concentrations acts through distinct pathways in normal versus benign prostatic hyperplasia-derived prostate stromal cellsEndocrinologyOctober 1, 2009Park II, Zhang Q, Liu V, Kozlowski JM, Zhang J, Lee C.

(2) "Molecular Proof of a Clinical Concept: Expression of Estrogen Alpha-, Beta-Receptors and G Protein-Coupled Estrogen Receptor 1 (GPER) in Histologically Assessed Common Nevi, Dysplastic Nevi and Melanomas""Medicina (Kaunas, Lithuania)"January 1, 0001"Spałkowska M, Dyduch G, Broniatowska E, Damiani G, Wojas-Pelc A."Littleton, CO, USA) (dilution 1:50, incubation 30 min); anti-GPER GPR30, rabbit monoclonal antibody NLS1183 (Novus Biologics, Littleton, CO, USA) (dilution 1:50, incubation 30 min), anti-progesterone receptor

(3) Pharmacologic Activation of the G Protein-Coupled Estrogen Receptor Inhibits Pancreatic Ductal AdenocarcinomaCellular and molecular gastroenterology and hepatologyJanuary 1, 0001"Natale CA, Li J, Pitarresi JR, Norgard RJ, Dentchev T, Capell BC, Seykora JT, Stanger BZ, Ridky TW."

(4) Activation of G protein-coupled estrogen receptor signaling inhibits melanoma and improves response to immune checkpoint blockadeeLifeJanuary 1, 0001"Natale CA, Li J, Zhang J, Dahal A, Dentchev T, Stanger BZ, Ridky TW."

(5) 17β-Estradiol induces nongenomic effects in renal intercalated cells through G protein-coupled estrogen receptor 1American journal of physiology. Renal physiologyJanuary 1, 0001"Hofmeister MV, Damkier HH, Christensen BM, Olde B, Fredrik Leeb-Lundberg LM, Fenton RA, Praetorius HA, Praetorius J."

(6) "Biology of the estrogen receptor, GPR30, in triple negative breast cancer"American journal of surgeryJanuary 1, 0001"Steiman J, Peralta EA, Louis S, Kamel O."

Be the First to Write a Review!