MOUSE ANTI POLY(ADP-RIBOSE) POLYMERASE-1 MCA1522G from Bio-Rad (AbD Serotec - FAB)

Product Specs
ItemMOUSE ANTI POLY(ADP-RIBOSE) POLYMERASE-1
CompanyBio-Rad
Price $289.00Supplier Page View Company Product Page
Catalog NumberMCA1522G
TargetPOLY(ADP-RIBOSE) POLYMERASE-1
NCBI Gene AliasesPPOL, ADPRT, ARTD1, PARP-1, ADPRT 1, Poly-PARP, PARS, PARP, ADPRT1, pADPRT-1
CloneA6.4.12
HostMouse
Quantity0.1 mg
FormatPurified IgG - liquid
IsotypeIgG1
ReactivityHamster,Mouse,Drosophila,Xenopus,Rat, Human
ApplicationsWestern Blotting,Immunohistology - Paraffin,Immunoprecipitation,Immunohistology - Frozen,ELISA,Immunofluorescence
ClonalityMonoclonal Antibody
NCBI Full Gene Namepoly(ADP-ribose) polymerase 1
ConcentrationIgG concentration 1.0 mg/ml

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Bio-Rad

Bio-Rad Laboratories, Inc. Life Science Research Group 2000 Alfred Nobel Drive

Hercules, California 94547

United States

Phone: 800-424 6723
800-879 2289

Company Profile

Website: http://discover.bio-rad.com

(1) BRCA2 prevents PARPi-mediated PARP1 retention to protect RAD51 filamentsNatureApril 1, 2025Lahiri S, Hamilton G, Moore G, Goehring L, Huang TT, Jensen RB, Rothenberg E.containing 150 mM NaCl led to precipitation of the protein. The anti-PARP1 antibody (Bio-Rad, cat: MCA1522G, Isotype: IgG1) was incubated with 50 μL (~0.50 mg) of Protein A/G magnetic beads (Pierce, cat: 88802)

(2) FTO suppresses DNA repair by inhibiting PARP1Nat CommunMarch 25, 2025Tianyi Zhu, Jing Zhi Anson Tan, Lingrui Zhang, He Huang, Sooraj S. Das, Flora Cheng, Pranesh Padmanabhan, Mathew J. K. Jones, Mihwa Lee, Albert Lee, et al.(clone 9E10, Santa Cruz Biotechnology, sc-40, WB 1:500), mouse anti-PARP1 (clone A6.4.12, Bio-Rad, MCA1522G, WB 1:1000, IF 1:250, PLA 1:250), mouse anti-PAR (clone 10HA, Trevigen, 4335-MC-100, WB 1:1000), mouse

(3) Poly ADP‐ribosylation regulates Arc expression and promotes adaptive stress-copingPsychopharmacology (Berl)January 14, 2025Eliyahu Dahan, Leah Pergamenshik, Tze’ela Taub, Arthur Vovk, Jade Manier, Raphael Avneri, Elad LaxALX-804–220-R100" ,PARP-1,Bio-Rad No.1806,"Monoclonal mouse anti-Poly(ADP-Ribose) Polymerase-1 antibody, clone A6.4.12, Bio-Rad, MCA1522G" ,Beta-actin,"Merck, No.3419587","Monoclonal mouse anti-beta-antibody, clone 4C2, Sigma-Aldrich, MABT825" ,Acetylated

(4) PARP1 and PARP2 stabilise replication forks at base excision repair intermediates through Fbh1-dependent Rad51 regulationNature CommunicationsDecember 1, 2018George E. Ronson, Ann Liza Piberger, Martin R. Higgs, Anna L. Olsen, Grant S. Stewart, Peter J. McHugh, Eva Petermann, Nicholas D. Lakinwere treated with 5 μg/mL Doxycyclin for 24 h. Antibodies used in this study were anti-PARP1 (Bio-Rad, MCA1522G; dilution 1:1000), anti-PARP2 (Enzo, ALX-804-639L; dilution 1:50), anti-PARP3 (A kind gift of F. Dantzer;

(5) Overlapping roles for PARP1 and PARP2 in the recruitment of endogenous XRCC1 and PNKP into oxidized chromatinNucleic acids researchMarch 17, 2017Hanzlikova H, Gittens W, Krejcikova K, Zeng Z, Caldecott KW.

(6) Poly(ADP-ribose) polymerase inhibitors activate the p53 signaling pathway in neural stem/progenitor cellsBMC neuroscienceJanuary 17, 2017Okuda A, Kurokawa S, Takehashi M, Maeda A, Fukuda K, Kubo Y, Nogusa H, Takatani-Nakase T, Okuda S, Ueda K, et al.

(7) XRCC1 mutation is associated with PARP1 hyperactivation and cerebellar ataxiaNatureJanuary 5, 2017Hoch NC, Hanzlikova H, Rulten SL, Tétreault M, Komulainen E, Ju L, Hornyak P, Zeng Z, Gittens W, Rey SA, et al.

(8) The XRCC1 phosphate-binding pocket binds poly (ADP-ribose) and is required for XRCC1 functionNucleic Acids ResearchAugust 18, 2015Claire Breslin, Peter Hornyak, Andrew Ridley, Stuart L. Rulten, Hana Hanzlikova, Antony W. Oliver, Keith W. CaldecottA300-231A; Bethyl Laboratories, Inc.), mouse anti-PAR (10H) Mab (1:1000), mouse anti-PARP1 Mab (1:1000, MCA1522G, Bio-Rad), mouse anti-Actin Mab (1:2000, A4700, Sigma), mouse anti-XRCC1 (33-2-5) Mab (23), or mouse

(9) Nucleolar Integrity Is Required for the Maintenance of Long-Term Synaptic PlasticityPLoS ONEAugust 4, 2014Kim D. Allen et al.the NP control, all cells were incubated overnight with primary ABs (mouse anti-PARP-1 (1∶500); Cat # MCA1522G, AbD Serotec and polyclonal anti-fibrillarin AB (1∶1000); Cat # ab5821, Abcam) in blocking solution.

(10) R-Loops in Proliferating Cells but Not in the Brain: Implications for AOA2 and Other Autosomal Recessive AtaxiasPLoS ONEMarch 17, 2014Abrey J Yeo, Olivier J Becherel, John E Luff, Jason K Cullen, Thidathip Wongsurawat, Piroon Jenjaroenpun, Piroon Jenjaroenpoon, Vladimir A Kuznetsov, Peter J McKinnon, Martin F Lavin

(11) Beyond DNA repair, the immunological role of PARP-1 and its siblingsImmunologyAugust 1, 2013Maria Manuela Rosado, Elisabetta Bennici, Flavia Novelli, Claudio Pioli

(12) PARP1 inhibition affects pleural mesothelioma cell viability and uncouples AKT/mTOR axis via SIRT1Journal of cellular and molecular medicineFebruary 1, 2013Giulia Pinton, Arcangela Gabriella Manente, Bruno Murer, Elvira De Marino, Luciano Mutti, Laura Moro

(13) Novel roles for KLF1 in erythropoiesis revealed by mRNA-seqGenome researchDecember 1, 2012Tallack MR, Magor GW, Dartigues B, Sun L, Huang S, Fittock JM, Fry SV, Glazov EA, Bailey TL, Perkins AC.anti-caspase 3, 9661 Cell Signaling Technology; anti-GATA1, sc-265 Santa Cruz Biotechnology; and anti-PARP, MCA1522G AbD Serotec. TUNEL assay Homogenized E14.5 fetal livers were assayed for apoptosis using the TUNEL

(14) FAT10 is a proteasomal degradation signal that is itself regulated by ubiquitinationMolecular Biology of the CellJanuary 1, 2012Samuel Buchsbaum, Beatrice Bercovich, Aaron CiechanoverSanta Cruz, CA), actin (clone C4; Millipore), FAT10 (PW9680; Enzo Life Sciences, Plymouth, PA), PARP-1 (MCA1522G; AbD Serotec, Raleigh, NC), the ribosomal protein S18 (clone E13; Santa Cruz Biotechnology). and human

(15) DNA repair protein biomarkers associated with time to recurrence in triple-negative breast cancerClinical cancer research : an official journal of the American Association for Cancer ResearchDecember 1, 2010Alexander BM, Sprott K, Farrow DA, Wang X, D'Andrea AD, Schnitt SJ, Collins LC, Weaver DT, Garber JE.MLH1 [mismatch repair (MMR); BioCare Medical, CM220], PARP1 [base excision repair (BER); AbD Serotec, MCA1522G], PAR [base excision repair (BER); Millipore, MAB3192], pMK2 [MAPKAPKinase2, DNA damage response (DDR);

(16) Aprataxin, poly-ADP ribose polymerase 1 (PARP-1) and apurinic endonuclease 1 (APE1) function together to protect the genome against oxidative damageHuman molecular geneticsNovember 1, 2009Harris JL, Jakob B, Taucher-Scholz G, Dianov GL, Becherel OJ, Lavin MF.

(17) Regulation of Claspin degradation by the ubiquitin-proteosome pathway during the cell cycle and in response to ATR-dependent checkpoint activationFEBS lettersJuly 24, 2006Bennett LN, Clarke PR.

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MOUSE ANTI POLY(ADP-RIBOSE) POLYMERASE-1

MOUSE ANTI POLY(ADP-RIBOSE) POLYMERASE-1

MOUSE ANTI POLY(ADP-RIBOSE) POLYMERASE-1 from Bio-Rad (AbD Serotec - FAB)

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MOUSE ANTI POLY(ADP-RIBOSE) POLYMERASE-1 from Bio-Rad (AbD Serotec - FAB)

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