CD278 (ICOS) Antibody Functional Grade 16-9948-82 from Thermo Fisher Scientific

Product Specs
ItemCD278 (ICOS) Antibody Functional Grade
CompanyThermo Fisher Scientific
Price Supplier Page
Catalog Number16-9948-82
Quantity100 µg
ApplicationsFlow Cytometry, Functional assay
Concentration1 mg/mL
Conjugate/TagFunctional Grade
FormatPBS with no preservative; pH 7.2
ReactivityHuman
TargetCD278 (ICOS)
IsotypeIgG1 kappa
CloneISA-3
HostMouse
NCBI Full Gene Nameinducible T cell costimulator
NCBI Gene AliasesAILIM, CD278, CVID1
ClonalityMonoclonal
PurityAffinity chromatography
Storage Temperature4° C
Antibody TypePrimary
Storage4°C

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Fax: 800-331-2286

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Website: www.thermofisher.com

(1) Non-coding autoimmune risk variant defines role for ICOS in T peripheral helper cell developmentNature communicationsMarch 9, 2024Kim T, Martínez-Bonet M, Wang Q, Hackert N, Sparks JA, Baglaenko Y, Koh B, Darbousset R, Laza-Briviesca R, Chen X, et al.either plate-bound anti-CD3 (Biolegend, 317302)/CD28 (Biolegend, 302943) or anti-CD3/ICOS (Invitrogen, 16-9948-82) antibodies over different time periods. Whole-cell lysate were obtained using Cell Lysis Buffer (Cellsignal,

(2) Inducible Costimulator-C-X-C Motif Chemokine Receptor 3 Signaling is Involved in Chronic Obstructive Pulmonary Disease PathogenesisInternational journal of chronic obstructive pulmonary diseaseJanuary 1, 2022Li DY, Chen L, Miao SY, Zhou M, Wu JH, Sun SW, Liu LL, Qi C, Xiong XZ.assess the influence of ICOS signaling on CXCR3 expression, anti-ICOS mAb (ISA-3; 5 µg/mL; eBioscience, 16–9948-82, USA) was added to the culture medium. Flow Cytometric Analyses Immune cells were washed twice with

(3) Impaired HA-specific T follicular helper cell and antibody responses to influenza vaccination are linked to inflammation in humanseLifeNovember 2, 2021Hill DL, Whyte CE, Innocentin S, Lee JL, Dooley J, Wang J, James EA, Lee JC, Kwok WW, Zand MS, et al.

(4) Changes in expression of PD-L1 on peripheral T cells in patients with melanoma and lung cancer treated with PD-1 inhibitorsScientific reportsJuly 28, 2021Dart SJ, Cook AM, Millward MJ, McDonnell AM, Chin WL, Hakeem MU, Meniawy TM, Bowyer SE.

(5) Functional SARS-CoV-2-Specific Immune Memory Persists after Mild COVID-19CellJanuary 7, 2021Rodda LB, Netland J, Shehata L, Pruner KB, Morawski PA, Thouvenel CD, Takehara KK, Eggenberger J, Hemann EA, Waterman HR, et al.

(6) IL-21-Deficient T Follicular Helper Cells Support B Cell Responses Through IL-27 in Patients With Chronic Hepatitis BFrontiers in immunologyJanuary 1, 2020Khanam A, Ayithan N, Tang L, Poonia B, Kottilil S.

(7) Dysregulated ICOS(+) proinflammatory and suppressive regulatory T cells in patients with rheumatoid arthritisExperimental and therapeutic medicineOctober 1, 2018Wang HX, Kang X, Chu S, Li H, Li X, Yin X, Qiu YR, Lai W.

(8) Distribution of circulating follicular helper T cells and expression of interleukin-21 and chemokine C-X-C ligand 13 in gastric cancerOncology lettersSeptember 1, 2018Meng X, Yu X, Dong Q, Xu X, Li J, Xu Q, Ma J, Zhou C.

(9) CXCL13-producing TFH cells link immune suppression and adaptive memory in human breast cancerJCI insightJune 2, 2017Gu-Trantien C, Migliori E, Buisseret L, de Wind A, Brohée S, Garaud S, Noël G, Dang Chi VL, Lodewyckx JN, Naveaux C, et al.

(10) CD28 family of receptors on T cells in chronic HBV infection: Expression characteristics, clinical significance and correlations with PD-1 blockadeMolecular medicine reportsAugust 1, 2016Tang ZS, Hao YH, Zhang EJ, Xu CL, Zhou Y, Zheng X, Yang DL.

(11) Polyfunctional Melan-A-specific tumor-reactive CD8(+) T cells elicited by dacarbazine treatment before peptide-vaccination depends on AKT activation sustained by ICOSOncoimmunologyMay 1, 2016Franzese O, Palermo B, Di Donna C, Sperduti I, Ferraresi V, Stabile H, Gismondi A, Santoni A, Nisticò P.were incubated for 24 h with plate-bound functional grade anti-ICOS agonist mAb (IgG1, eBioscience, 16-9948-82 ) (12.5 µg/mL) in the presence of anti-CD3, before polyfunctional analysis. For some experiments, the

(12) Tumor-infiltrating plasmacytoid dendritic cells promote immunosuppression by Tr1 cells in human liver tumorsOncoimmunologyJune 1, 2015Pedroza-Gonzalez A, Zhou G, Vargas-Mendez E, Boor PP, Mancham S, Verhoef C, Polak WG, Grünhagen D, Pan Q, Janssen H, et al.

(13) Inducible costimulator: a modulator of IFN-gamma production in human tuberculosisJournal of immunology (Baltimore, Md. : 1950)May 15, 2006Quiroga MF, Pasquinelli V, Martínez GJ, Jurado JO, Zorrilla LC, Musella RM, Abbate E, Sieling PA, García VE.

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CD278 (ICOS) Antibody Functional Grade from Thermo Fisher Scientific

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CD278 (ICOS) Antibody Functional Grade from Thermo Fisher Scientific

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