Spatial proteomics refers to a class of analytical approaches that map protein expression directly within tissue architecture, providing biologically and clinically relevant insight into disease mechanisms and therapeutic response. Advances in spatial proteomic technologies have enabled researchers to understand cellular dynamics in healthy and diseased tissues with unparalleled depth and breadth. These capabilities have direct implications for drug discovery and development, enabling deeper understanding of disease biology, identification of novel and context-specific drug targets, and improved stratification of patients most likely to benefit from a given therapy.
In this application note from Leica, discover solutions that support spatial proteomics workflows across discovery, translational, and clinical research.