Mammalian cell culture is a cornerstone of biological research, driving advances in protein expression, cell line development, and viral vector production. However, traditional methods often present challenges, including contamination risks and throughput limitations. The CellXpert™ CS220 CO2 incubator shaker from Eppendorf is engineered to address these challenges, accelerating research projects while maintaining the highest standards of cell culture integrity.
Addressing critical needs in cell culture
The CellXpert™ CS220 is designed to minimize the risk of costly project delays. It stands out as the first CO2 incubator shaker to integrate the stringent contamination prevention measures typically found in CO2 incubator-based cell culture into a shaker platform.
The CellXpert™ CS220 addresses key problems in mammalian cell culture. Traditional shakers are vulnerable to contamination, which can compromise experiments and lead to significant delays. The CellXpert™ CS220 CO2 incubator shaker mitigates this risk with its integrated 180°C sterilization function, a feature typically reserved for high-end CO2 incubators. Many laboratories require higher throughput to efficiently conduct screenings and process development. The CellXpert™ CS220 maximizes throughput per run, allowing researchers to accomplish more with each experiment. Laboratory space is often at a premium. The CellXpert™ CS220 offers the highest platform size to footprint ratio, optimizing the use of valuable lab space without sacrificing performance.
Key advantages of the CellXpert™ CS220
The CellXpert™ CS220 stands out from traditional shakers and incubators with several key advantages. Designed for maximum efficiency, it accommodates a higher sample capacity per run, boosting productivity. Its optimized platform-to-footprint ratio makes the most of limited lab space, offering ample capacity without occupying excessive room. To ensure a contamination-free environment, the system features an integrated 180°C sterilization routine, providing robust protection for cell cultures and experiments. Additionally, it allows for quick and easy disinfection within minutes, maintaining a consistently clean and sterile cell culture environment.
Versatile applications across diverse research areas
The CellXpert™ CS220 is a versatile solution for a wide range of mammalian cell culture applications. It supports the expansion of suspension cells, such as CHO and HEK293, for protein expression studies while offering high-throughput capabilities ideal for screening multiple conditions and cell lines. With a stable and controlled environment, the system ensures consistency and reliability in cell line development, early process optimization, and scale-up efforts. Additionally, it facilitates viral vector production, including adenovirus, adeno-associated virus (AAV), and lentivirus (LV), and can be used for bioreactor inoculum preparation. The CellXpert™ CS220 also enables the cultivation of mesenchymal and induced pluripotent stem cells in normoxic conditions, supporting advanced applications like microcarrier-based reprogramming and exosome production.
Conclusion
The CellXpert™ CS220 CO2 incubator shaker from Eppendorf marks a major advancement in mammalian cell culture technology. Designed to address key challenges such as contamination, throughput, and space efficiency, it helps researchers to accelerate their projects and achieve more reliable results. With its versatility and advanced features, the CS220 is an ideal solution for applications ranging from protein expression to viral vector production.