Single-cell RNA sequencing (scRNA-seq) has revolutionized how scientists understand cellular function, plasticity, and heterogeneity, letting them construct cellular atlases. In addition to the Human Cell Atlas project, which seeks to profile every cell in the human body, thousands of single-cell atlases exist, covering a variety of tissues, organs, species, and pathologies. Using these atlases as reference materials, scientists are now looking to determine how cells change during aging, disease, and therapeutic intervention.
Download this ebook to learn more about that shift, exploring the experimental designs, annotation strategies, and computational pipelines that turn atlas-scale data into mechanistic insights.