The laboratory mouse is one of the main research animals used for modeling human disease. Murine-human genetic similarities, in particular, have led to the development of genetically engineered mouse models where the genome is manipulated to mimic human disease or to further investigate the physiological relevance of a gene or mechanism. The recent advent of CRISPR/Cas gene editing technology has made this much more feasible, efficient, and accessible. Nonetheless, creating a genetically engineered mouse model can be a daunting endeavor.
In this ebook from GemPharmatech, learn more about how private companies can provide comprehensive support throughout the entire mouse model creation process.