Chimeric antigen receptor-T cell (CAR-T) therapies have tremendous potential for cancer treatment. However, developing these therapies can be complicated as CAR-T cells must be monitored for quality and functionality continuously during production. A myriad of technologies are used to ensure the appropriate cell types are isolated, their phenotype assessed, and their expansion monitored.
The articles in this eBook specifically focus on the use of advanced flow cytometry and live-cell analysis in CAR-T development