
DNA Damage Assay kits contain the necessary reagents to measure different markers of DNA damage, which can result from reactive oxygen species (ROS) and UV exposure. DNA damage assay kits can utilize different assay mechanisms, depending on the type of damage. One approach is to tag the AP sites that indicate oxidative stress with an Aldehyde Reactive Probe (ARP), which are then biotinylated and quantified using a colorimetric assay. Another method detects oxidative DNA damage via 8-OHdG markers with capture and detection antibodies. UV-damage induced cyclobutane pyrimidine dimers (CPDs) may use specific anti-CPD antibodies in cultured cells. When choosing an assay kit, consider important specifications such as the assay detection range, recommended sample types, and the components included within the kit. Visit the supplier page for more details.
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