
DNA Damage Assay kits contain the necessary reagents to measure different markers of DNA damage, which can result from reactive oxygen species (ROS) and UV exposure. DNA damage assay kits can utilize different assay mechanisms, depending on the type of damage. One approach is to tag the AP sites that indicate oxidative stress with an Aldehyde Reactive Probe (ARP), which are then biotinylated and quantified using a colorimetric assay. Another method detects oxidative DNA damage via 8-OHdG markers with capture and detection antibodies. UV-damage induced cyclobutane pyrimidine dimers (CPDs) may use specific anti-CPD antibodies in cultured cells. When choosing an assay kit, consider important specifications such as the assay detection range, recommended sample types, and the components included within the kit. Visit the supplier page for more details.
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- The DNA Damage ELISA Kit from Arbor Assays quantitatively measures oxidized guanine species, including 8-OHdG, in serum,...
- 5 x 96 tests
- Competitive ELISA
- The DNA Damage ELISA Kit from Arbor Assays quantitatively measures oxidized guanine species, including 8-OHdG, in serum,...
- 1 x 96 tests
- Competitive ELISA
Kamiya Biomedical Company
- Colorimetric assay for the quantification of abasic sites (a marker for oxidative DNA damage) in purified genomic DNA.
- 20 tests
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- DNA damage in cells exposed to ultraviolet (UV) radiation plays significant roles in cell-cycle arrest, activation of ...
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- Apurinic/apyrimidinic (AP) sites are one of the major types of DNA lesions formed during the course of base excision and...
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