Malate Assay Kits

Malate assay kits include essential reagents to measure the abundance or concentration of malate in biological samples. Malate is a dicarboxylic acid involved in the TCA cycle, Calvin cycle, and the metabolism of carbohydrates, fats, and proteins. Malate assays generally involve a reaction with a chromogenic or fluorometric substrate, which can be mediated by the enzyme malate dehydrogenase. Another mechanism couples a reaction with another enzyme and luciferin to generate a luminescent signal. Malate assays are used in a variety of applications, including studying pathways such as the TCA cycle, gluconeogenesis, glyoxylate cycle and the malate-aspartate shuttle, studying non-fermentative growth, and investigating metabolic alterations in cancer cells. When choosing an assay kit, consider important specifications such as the assay detection range, recommended sample types, and the components included within the kit. Visit the supplier page for more details.