High Fidelity Polymerases

High-fidelity polymerases are enzymes that offer a high level of accuracy for molecular applications requiring low-error DNA replication. Many of these are thermostable fusion polymerases that include a proofreading domain to correct for any errors during replication. Many also feature DNA-binding domains that facilitate efficient, highly processive amplification. High-fidelity polymerases are used in cloning for protein expression, next-generation sequencing, SNP analysis, hot-start PCR, and high-fidelity PCR. Browse the products below to find the high-fidelity polymerase that best suits your research needs.