Intravital Microscopy System from Scintica Instrumentation

Product Specs
ItemIntravital Microscopy System
CompanyScintica Instrumentation
Price Get Pricing Get Quote for this Product
Catalog NumberIVM-000-001-0011 / IVM-200-001-0002 / IVM-200-001-0001 / IVM-100-001-0001
TypeTwo-Photon and Confocal Microscopy System
QuantityEA
SpeciesMice, rats, and animals of similar size, marmosets, rabbits
LightingConfocal laser unit and optional tunable or compact two-photon laser unit (model dependent)
Excitation WavelengthConfocal lasers: 405/488/561/640 nm; Two-photon: 690-1050 nm (tunable) or fixed 920 nm (model dependent)
Scanning SpeedPolygonal mirror (Fast axis scanning, Max. 66 kHz)
Galvano scanner (Slow axis scanning, Max. 200 ms/step)
ObjectivesMax. 5 objectives are mountable on S/W controlled motorized turret (1X – 100X)
Compatible for commercial objectives
Field of View (FOV)100 x 100 µm ² – 10 x 10 mm²
ResolutionMax. 2,048 x 2,048 pixels
SpeedImaging Speed:
Standard: 30 fps @ 512 x 512 pixels
(Optional) High Speed: 60 fps @ 512 x 512 pixels
(Optional) Ultra High Speed: 100 fps @ 512 x 512 pixels
StageIn Vivo Animal Stage - (All Models)
3D Stage:
Travel Range: 50,000 x 50,000 x 75,000 µm (XYZ)
Micromanipulation (Max. 0.2 µm resolution)
3-Axis independent control with Jog Dial & S/W

Features

Integrated heated animal stage with physiological controller and inhalation anesthesia inlet/outlet; ultrafast scanning; motion compensation; 4-color simultaneous imaging; 4D imaging (3D stacks over time); tissue stabilizing holders and window chamber kits for longitudinal imaging.

Additional Product Information

Animal Motion Compensation:
F4D In Vivo Imaging Motion Compensation:

XY motion compensation: Averaged image acquisition with motion artifact compensation

Z motion compensation: Image-based sample Z position adjustment for long-term intravital microscopic imaging & sample tracking (Feedback-loop automatic stage control)

T motion compensation: Image-based image XY position adjustment for long-term intravital microscopic imaging & sample tracking (Feedback-loop automatic stage control)

Combination of above three compensation for 4D in vivo motion compensation, Controllable by IVM Engine software

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Scintica Instrumentation

721 Tristar Dr

Webster, TX 77598

United States

Phone: +1 (832) 548 0895

Email: moreinfo@scintica.com

Company Profile

Website: scintica.com

(1) Pericytes promote metastasis by regulating tumor local vascular tone and hemodynamicsNature communicationsAugust 2, 2025Li X, Yan S, Wu X, Miao Q, Zhang D, Mai W, Han S, Tang Z, Ye M, Zhang S, et al.

(2) Preserving spatial and quantitative information in unpaired biomedical image-to-image translationCell Rep MethodsJune 16, 2025You JY, Eom M, Choi TI, Cho ES, Choi J, Lee M, Shin C, Moon J, Kim E, Kim P, et al.

(3) Perivascular Niche-Resident Alveolar Macrophages Promote Interstitial Pneumonitis Related to Trastuzumab Deruxtecan TreatmentCancer researchJune 2, 2025Wei Q, Yang T, Zhang Z, Wang F, Yang Y, Zhu J, Zhu X, Li Y, Xing Y, Lu Y, et al.

(4) Myo-inositol trispyrophosphate prevents right ventricular failure and improves survival in monocrotaline-induced pulmonary hypertension in the ratBritish journal of pharmacologyOctober 1, 2024Oknińska M, Paterek A, Grzanka M, Zajda K, Surzykiewicz M, Rolski F, Zambrowska Z, Torbicki A, Kurzyna M, Kieda C, et al.

(5) Deciphering perivascular macrophages and microglia in the retinal ganglion cell layersFrontiers in cell and developmental biologyJanuary 1, 2024Jeon J, Park YS, Kim SH, Kong E, Kim J, Yang JM, Lee JY, Kim YM, Kim IB, Kim P.

(6) Stepwise transmigration of T- and B cells through a perivascular channel in high endothelial venulesLife science allianceAugust 1, 2021Choe K, Moon J, Lee SY, Song E, Back JH, Song JH, Hyun YM, Uchimura K, Kim P.

(7) Exosome-based delivery of super-repressor IκBα relieves sepsis-associated organ damage and mortalityScience advancesApril 1, 2020Choi H, Kim Y, Mirzaaghasi A, Heo J, Kim YN, Shin JH, Kim S, Kim NH, Cho ES, In Yook J, et al.

(8) A Novel Pancreatic Imaging Window for Stabilized Longitudinal In Vivo Observation of Pancreatic Islets in Murine ModelDiabetes & metabolism journalFebruary 1, 2020Park I, Hong S, Hwang Y, Kim P.

(9) Delivery of Periodontopathogenic Extracellular Vesicles to Brain Monocytes and Microglial IL-6 Promotion by RNA CargoFrontiers in molecular biosciencesJanuary 1, 2020Ha JY, Choi SY, Lee JH, Hong SH, Lee HJ.

(10) Intravital imaging of a pulmonary endothelial surface layer in a murine sepsis modelBiomedical optics expressMay 1, 2018Park I, Choe K, Seo H, Hwang Y, Song E, Ahn J, Hwan Jo Y, Kim P.

(11) In vivo cellular-level real-time pharmacokinetic imaging of free-form and liposomal indocyanine green in liverBiomedical optics expressOctober 1, 2017Hwang Y, Yoon H, Choe K, Ahn J, Jung JH, Park JH, Kim P.

(12) Caspase-8 controls the secretion of inflammatory lysyl-tRNA synthetase in exosomes from cancer cellsThe Journal of cell biologyJuly 3, 2017Kim SB, Kim HR, Park MC, Cho S, Goughnour PC, Han D, Yoon I, Kim Y, Kang T, Song E, et al.

(13) Amelioration of sepsis by TIE2 activation-induced vascular protectionScience translational medicineApril 20, 2016Han S, Lee SJ, Kim KE, Lee HS, Oh N, Park I, Ko E, Oh SJ, Lee YS, Kim D, et al.

(14) In vivo analysis of THz wave irradiation induced acute inflammatory response in skin by laser-scanning confocal microscopyOptics expressMay 19, 2014Hwang Y, Ahn J, Mun J, Bae S, Jeong YU, Vinokurov NA, Kim P.

(15) Endoscopic time-lapse imaging of immune cells in infarcted mouse heartsCirculation researchMarch 15, 2013Jung K, Kim P, Leuschner F, Gorbatov R, Kim JK, Ueno T, Nahrendorf M, Yun SH.

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