STELLARIS Cryo Confocal Light Microscope from Leica Microsystems

Description

The STELLARIS Cryo is a confocal light microscope system that helps you to target your area of interest for cryo-electron tomography (CryoET). The STELLARIS Cryo gives you the precision to target reliably, while still offering superior performance you can count on and sample safety for your experiments.

Your Benefits:

Resolve and identify intracellular targets in 3D
Reduce handling steps in your workflow
Observe finer details in every sample, capture faintest signals, and gather more precise and reliable data across the spectrum.

STELLARIS Cryo features:

LAS X Coral Cryo software – allows for precise positioning of open format coordinate markers in a nanometer scale.
Two modes of ice checking - a fast camera overview and a confocal reflection mode to determine the ice thickness in 3D. The Cryo CLEM objective HC PL APO 50x/0.90 has been developed to fulfil the specific needs of cryo light microscopy, offering you the advantages of super-resolution without the need for liquid immersion.
TauSense technology - Due to the deep temperature during cryo workflows such as Coral Cryo, the emission and excitation windows of fluorophores converge. TauSense allows you to separate overlapping fluorophores due to their different average photon arrival times.

Product Specs
ItemSTELLARIS Cryo Confocal Light Microscope
CompanyLeica Microsystems
Price Get Pricing Get Quote for this Product
Catalog NumberSTELLARIS Cryo
ApplicationsCryoET, 3D Imaging, FRET, FRAP, Multicolor confocal imaging, Light Sheet

Add to Compare List

Leica Microsystems

10 Parkway North Blvd., Suite 300

Deerfield, Illinois 60015

United States

Phone: 800 248 0123

Company Profile

Website: www.leica-microsystems.com

(1) Fully genetically encoded low-molecular-weight protein tags with defined shapes for direct molecular identification by cryo-electron tomographybioRxivJanuary 24, 2026Feng Luo, Rong Sun, Oliver Chalkley, Pingping Li, Qiangjun Zhou(Cryo-CLEM) Cryo-FIB-milled lamellae of HeLa cells expressing TOM70NTD-V12-GFP or TOM70NTD-Δ6-GFP were imaged using Leica STELLARIS Cryo-confocal microscope. FIB-milled grids were transferred with a Leica EM VCM under fresh liquid nitrogen

(2) Functional classification of tauopathy strains reveals the role of protofilament core residuesSci AdvJanuary 24, 2025Jaime Vaquer-Alicea, Victor A. Manon, Vaibhav Bommareddy, Peter Kunach, Ankit Gupta, Jim Monistrol, Valerie A. Perez, Hung Tri Tran, Nil Saez-Calveras, Siling Du, et al.600-Å crossover distance. Cryo-CLEM imaging of DS13 Vitrified samples were imaged at −195°C using the STELLARIS 5 Cryo Confocal Light Microscope from Leica Microsystems, which was equipped with a cryo-stage, power HyD detectors, and a white light

(3) Recent advances in correlative cryo-light and electron microscopyCurrent Opinion in Structural BiologyDecember 1, 2024Joshua A. Pierson, Jie E. Yang, Elizabeth R. Wrightsystems have been introduced, including several commercial options such as the ZEISS Airyscan and Leica Stellaris cryo-confocal. These cryo-confocal microscopes regularly achieve resolutions of 250-300 nm laterally and

(4) YY1 is involved in homologous recombination inhibition at guanine quadruplex sites in human cellsNucleic Acids ResearchJuly 22, 2024Xinyu Cui, Chengwen Zhang, Chunqing Fu, Jinglei Hu, Tengjiao Li, Lin LiMedium (Beyotime, P0126). Three biological replicates were performed. Images were acquired on a Leica Stellaris 5 Cryo Confocal Light Microscope. Fluorescence illumination was with a xenon source and Alexa 488, Alexa 594, and DAPI fluorescent filter

(5) Correlative montage parallel array cryo-tomography for in situ structural cell biologyNature MethodsOctober 1, 2023Jie E. Yang, Matthew R. Larson, Bryan S. Sibert, Joseph Y. Kim, Daniel Parrell, Juan C. Sanchez, Victoria Pappas, Anil Kumar, Kai Cai, Keith Thompson, et al.preservation of an ROI in the lamella, lamellae were transferred to the Leica EM Cryo-CLEM THUNDER28 or Leica Stellaris cryo-confocal system and a z-stack of the same channels was collected. With the post-correlation on-lamella

(6) Missense variant interaction scanning reveals a critical role of the FERM domain for tumor suppressor protein NF2 conformation and functionLife Science AllianceAugust 1, 2023Christina S Moesslacher, Elisabeth Auernig, Jonathan Woodsmith, Andreas Feichtner, Evelyne Jany-Luig, Stefanie Jehle, Josephine M Worseck, Christian L Heine, Eduard Stefan, Ulrich Stelzlaccording to the manufacturer’s instructions. Fluorescence microscope images were acquired by using a STELLARIS 5 Cryo Confocal Light Microscope (Leica) equipped with a HC PL APO 63x/1,40 OIL CS2 objective. For excitation, a 405 nm (Hoechst 33342)

Be the First to Write a Review!