Crest X-Light Series Spinning Disk Confocal from Nikon Instruments Inc.

Product Specs
ItemCrest X-Light Series Spinning Disk Confocal
CompanyNikon Instruments Inc.
Price Get Pricing Get Quote for this Product
Catalog NumberInquire
TypeSpinning Disk Confocal
QuantityEA
ApplicationsWidefield, fluorescence, 3D imaging of tissues, organoids, spheroids, and small organisms
Light SourceLED

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Nikon Instruments Inc.

1300 Walt Whitman Road

Melville, New York 11747

United States

Phone: 800-526-4566
1-800-52-NIKON (1-800-526-4566)
Fax: 631-547-0306

Company Profile

Website: https://www.microscope.healthcare.nikon.com/

(1) Multi-omic analysis reveals nitric oxide dependent remodeling in classically activated macrophages and identifies negative regulation mediated by AKR1A1Redox BiologyJune 1, 2026Nicholas L. Arp, Uzziah S. Urquiza, Marcel Morgenstern, Jonathan H. Schrope, James A. Votava, Steven V. John, Jack J. Stevens, Felicia Deng, Anna Huttenlocher, Joshua J. Coon, et al.STX) set to 37 °C and 5% CO2 for confocal imaging with a Nikon Eclipse Ti2 microscope equipped with a Crest X-light V3531 spinning disc unit and a Kinetix22 monochrome camera. Z-stacks were acquired with a Plan Apochromat

(2) Oncogenic and tumor-suppressive forces converge on a progenitor niche at the benign-to-malignant transitionCellMay 14, 2026José Reyes, Isabella Del Priore, Andrea C. Chaikovsky, Nikhita Pasnuri, Ahmed M. Elhossiny, Jin Park, Philipp Weiler, Tobias Krause, Andrew Moorman, Catherine Snopkowski, et al.regions of interest in the p53-stained slide. We acquired images using a 20X Plan APO objective and the Crest X-Light V2 LFOV25 Spinning Disk Confocal attached to our Nikon T2i Eclipse microscope, collecting fields of

(3) Biocompatible Self-Healing Hydrogel for VAT 3D PrintingACS Materials AuMay 13, 2026Maria D’Aloia, Désirée Baruffaldi, Sandra Dirè, Emanuela Callone, Angelo Angelini, Candido Fabrizio Pirri, Ignazio Roppolo, Francesca Frascellathe constructs were visualized with a microscope (Eclipse Ti2 Nikon, Tokyo, Japan) equipped with a Crest X-Light spinning disk confocal microscope and a Lumencor SPECTRA X light engine. To evaluate cell morphology,

(4) Human iPSC-Derived Blood Vessel Organoids for Studying Chronic Hypoxia-Induced Microvascular DysfunctionJ Histochem CytochemMay 11, 2026Paola Serrano Martinez, Maxime Cammeraat, Amber Teppema, Cornelis J. F. van Noorden, Reinier O. Schlingemann, Ingeborg KlaassenBV, Amstelveen, The Netherlands) equipped with a CrestOptics X-Light spinning disk (pinhole 50 µm, CrEST X-Light V3, Nikon Europe BV) or a STELLARIS 8 confocal microscope (Leica Microsystems, Wetzlar, Germany). Acquired

(5) A branching cell-fate decision in biofilm dispersal enables long-term surface persistencebioRxivMay 5, 2026Sandhya Kasivisweswaran, Jojo A. Prentice, Andrew A. Bridgesmicroscopy (Oko Labs). Timelapse imaging was conducted on a motorized Nikon Ti2-E microscope equipped with a CREST X-Light V3 spinning disk unit and a back-thinned sCMOS camera (Hamamatsu Orca Fusion BT). Imaging utilized either

(6) Topographic structure and function of locus coeruleus norepinephrine neuronsbioRxivApril 10, 2026Zhixiao Su, Polina Kosillo, Kanghoon Jung, Shuonan Chen, Mathew T. Summers, Alex Piet, Han Hou, Kenta M. Hagihara, Drew Friedmann, Olivia Ho-Shing, et al.performed using Illumina MiSeq Reagent Nano Kit v2 (300-cycles) and imaged on a Nikon Ti2-E microscope with Crest xlight v3 spinning disk confocal, photometrics Kinetix camera, and Lumencor Celesta laser. All images were

(7) Cell type-specific barcoding reveals the single-neuron projectional architecture of the mouse midbrain dopaminergic systembioRxivApril 4, 2026Hyopil Kim, Cheng Xu, Craig Washington, Caleb Shi, Maggie Lowman, Justus M. Kebschulltotal 2 rounds of barcode sequencing. Imaging was performed using a spinning-disk confocal microscope (Crest X-Light V3) mounted on a Nikon Ti2-E with a 25x oil-immersion objective (NA 1.05). Illumina fluorophores were

(8) CREsted: modeling genomic and synthetic cell-type-specific enhancers across tissues and speciesNature MethodsApril 2, 2026Niklas Kempynck, Seppe De Winter, Casper H. Blaauw, Vasileios Konstantakos, Eren Can Ekşi, Sam Dieltiens, Darina Abaffyová, Valérie Bercier, Ibrahim I. Taskiran, Gert Hulselmans, et al.imaged for GFP fluorescence on a spinning-disk confocal microscope consisting of a Nikon Ti2 body and Crest X-Light V2 spinning disk using a ×10 Plan Apo Lambda lens with numerical aperture of 0.45 and a ×20 Plan Apo

(9) Meningeal-tumor interactions define distinct modes of leptomeningeal colonization in Group 3 medulloblastomaActa Neuropathologica CommunicationsApril 1, 2026Leyre Jimenez Garcia, Lindsay N. Ryan, Amy C. Gross, Annika M. Albrecht, Jefferson H. Walters, Jeffrey R. Leonard, Ryan D. Roberts, James B. Reinecke(Invitrogen, 00495802). Microscopy and image analysis Confocal microscopy images were obtained using a Crest-X-Light V3 spinning disk confocal on a Nikon Ti2-E inverted microscope, equipped with either a Hamamatsu ORCA

(10) DYN-1 regulates SPD-2 and PLK-1 localization and mitotic spindle pole organizationMolecular Biology of the CellApril 1, 2026Carter Dierlam, Stephanie Held, Jiya Hastings, Livinus Anyanwu, Robert H. Newman, Jyoti Iyerand Supplemental Figure S3. A Nikon Ti2-E inverted microscope (Nikon Instruments) outfitted with a CREST X-Light V3 spinning-disk confocal module, a motorized XY stage with encoder feedback, and a 600-µm Z-piezo drive

(11) FDA-approved PDE4 inhibitors alleviate the dominant toxicity of ALS-FTD-associated CHCHD10S59L in Drosophila and human cellsiScienceMarch 20, 2026Swati Maitra, Do-Won Ham, Minwoo Baek, Yun-Jeong Choe, Nam Chul Kim(SouthernBiotech). Images were obtained with a LSM 710 (Zeiss, X63, 1.4 NA) confocal microscope or Nikon Crest X-light 2 spinning disc confocal microscope (Nikon). Co-localization was analyzed with ImageJ software. Primary

(12) DYN-1 regulates SPD-2 and PLK-1 localization and mitotic spindle pole organizationMol Biol CellMarch 18, 2026Carter Dierlam, Stephanie Held, Jiya Hastings, Livinus Anyanwu, Robert H. Newman, Jyoti Iyerand Supplemental Figure S3. A Nikon Ti2-E inverted microscope (Nikon Instruments) outfitted with a CREST X-Light V3 spinning-disk confocal module, a motorized XY stage with encoder feedback, and a 600-µm Z-piezo drive

(13) Evidence that xylazine disrupts skin homeostasis by acting on epithelial cells through the kappa opioid receptorDisease Models & MechanismsMarch 6, 2026Tanner F. Robertson, Adam Horn, Frances M. Smith, Anna HuttenlocherThe remaining fluorescence microscopy was performed on a Nikon Eclipse Ti2 microscope equipped with a Crest X-light V3 spinning disc unit and Kinetix22 monochrome camera. All imaging was performed using a Plan Apochromat

(14) The endocytic fission protein EHD1 interacts with tubulin and regulates microtubule functionBiochimica et Biophysica Acta (BBA) - Molecular Cell ResearchMarch 1, 2026Bazella Ashraf, Journey Reddick-Umoja, Jasmyn Grant, Jyoti Iyer, Naava Naslavsky, Steve Caplanelegans embryo imaging: A Nikon Ti2-E inverted microscope (Nikon Instruments, Inc.) equipped with a CREST X-Light V3 spinning-disk confocal system, a motorized XY stage with encoder, and a 600 μm Z piezo stage was

(15) A quantitative framework for multiscale analysis of Candida albicans biofilm developmentBiofilmFebruary 28, 2026Kai Li, Samantha Skivens, J. Edward F. Green, Alexander K.Y. Tam, Daniel R. Pentland, Hella Baumann, Campbell W. Gourlay, Benjamin J. Binder, Philippe P. Laissueof view with a 1.5× tube lens (Nikon Corporation, Tokyo, Japan). The microscope was equipped with a Crest X-Light V3 Spinning Disc Confocal (Crestoptics S.p.A., Rome, Italy), but used in widefield fluorescence mode.

(16) Dysregulation of the DNA damage response by phosphorothioate antisense oligonucleotidesNature CommunicationsFebruary 27, 2026Linn Hjelmgren, Qianyu Zhou, Sandro Schmidli, Manon Gloudemans, Tomasz Czapik, Samantha Roudi, Malgorzata Honcharenko, Daniel W. Hagey, Samir EL Andaloussi, Marianne Farneboimaging cells were kept at 37 °C and 5% CO2. Images were acquired each minute during 1 h with a Nikon CrEST X-Light V3 Spinning Disk Confocal Microscope equipped with a 60x oil objective, and then processed with the

(17) A TRPV4-dependent calcium signaling axis regulates lamellipodial actin architecture to promote cell migrationCurr BiolFebruary 23, 2026Ernest Iu, Alexander Bogatch, Wenjun Deng, Jonathan D. Humphries, Changsong Yang, Fernando R. Valencia, Chengyin Li, Christopher A. McCulloch, Guy Tanentzapf, Tatyana M. Svitkina, et al.Apo TIRF objectives, a dynamic focusing system to correct for focus drift (PFS, Nikon Instruments), a CREST X-Light V2 LFOV25 (CrestOptics), a 7-color Celesta light engine (Lumencor) and a Prime95b sCmos camera (Photometrics). For

(18) MYC modulates TOP2A diffusion to promote substrate detection and activityNature CommunicationsFebruary 9, 2026Donald P. Cameron, Kathryn Jackson, Alessia Loffreda, Carl Möller, Vladislav Kuzin, Matteo Mazzocca, Evanthia Iliopoulou, Hallgerdur Kolbeinsdottir, Andrej Paluda, Evgeniya Pavlova, et al.bottom of the well and again focusing 25 μm higher within the well. Imaging was done using a Nikon CrEST X-Light V3 spinning disk microscope. Analysis was done using CellProfiler79. Droplet assays were performed in

(19) Leukocyte-epithelial physical contacts mediate interstitial migration in vivoResearchSquareFebruary 5, 2026Jonathan H. Huttenlocher, Jonathan Robertson, Tanner Robertson, Jack J. Stevens, Clyde W. Stevens, Clyde Tinnen, Julie Rindy, Emilie Rochon, David J. Rochon, David Huttenlocher(CellVis). Live imaging of zebrafish was performed using a Nikon Eclipse Ti2 microscope equipped with a Crest X-light V3531 spinning disc unit and a Kinetix22 monochrome camera. Images were acquired using either Plan Apochromat

(20) Molecular Motors Orchestrate Pause-and-Run Dynamics to Facilitate Intracellular TransportBiomoleculesFebruary 2, 2026Yusheng Shen, Kassandra M. Ori-McKenneythe Perfect Focus System (Nikon, Tokyo, Japan), equipped with a Plan Apo 60× NA 1.40 oil objective, a Crest X-Light V3 spinning disk confocal head (Crest-Optics, Rome, Italy), a Celesta light engine (Lumencor, Beaverton,

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