Amersham™ Typhoon™ Laser Scanner from Cytiva

Product Specs
ItemAmersham™ Typhoon™ Laser Scanner
CompanyCytiva Life Sciences
Price Get Pricing Get Quote for this Product
Catalog Number29187191 / 29187193 / 29187194 / 29238583 / 29264463
Dimensions(WxDxH) 900 x 800 x 400 mm
QuantityEA
ApplicationsIdeal for versatile imaging and precise quantitation of fluorescent, colorimetric, and radiolabeled nucleic acids and proteins, phosphor imaging, fluorescence red, green, blue, and NIR, OD, and sample types (imaging plates, gels, plates, tissue slides, membranes) — from narrow to very large samples.
TypeLaser-Scanner
VoltageAC100—240V~, Voltage variation±10%
LasersLD488, SHG532, LD635, LD685, LD785
Scan Area40 x 46 cm
Pixel Sizes10, 25, 50, 100 or 200 µm and a 1000 µm pre-scan
FilterIP Fltr 390BP, Cy2 Fltr 525BP20, Cy3 Fltr 570BP20, Cy5 Fltr 670BP30, IRshort Fltr 720BP20, IRlong Filtr 825BP30
Resolution10, 25, 50, 100 or 200 µm and a 1000 µm pre-scan
Field of View (FOV)40 x 46 cm
InterfaceMultiple laser options
DetectionFluorescence, phosphor imaging, densitometry, and chemiluminescence (Dark scan), 2xNIR and G fluorescence
Wavelength(s)515 to 840 nm
SoftwareMelanie 9, Image integrity checker
Light SourceLaser light
ModeFluorescence, phosphor imaging, densitometry, and chemiluminescence (Dark scan), 2xNIR fluorescence

Specifications/Features

Accurate quantitation: detect signals from as low as 3 pg of protein and differences across a dynamic range with greater than five orders of magnitude
High resolution: resolve fine details in your sample with a pixel resolution of as low as 10 µm
High sample throughput:large scanning area of 40 × 46 cm enables the simultaneously imaging of up to 20 gels or blots, measuring 10 × 8 cm in size, or up to 9 multiwell plates in a single scan
Versatile: one system to image multifluorescent-,radioisotope-labeled, and colorimetric samples on gels, membranes, multiwell plates, culture dishes, glass slides, and tissue sections
Upgrade kits & custom filter box to offer the maximum options in fluorescence imaging and the best the Typhoon™ system has to offer

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Cytiva Life Sciences

Company Profile

Website: Cytiva Life Sciences

(1) Mouse TAPBPR shows functional similarity to human TAPBPR in shaping the MHC-I immunopeptidomeFront ImmunolApril 15, 2026Juliana Bernardi Aggio, Marcel Wacker, William Guo, Arwen F. Altenburg, Ida Hafstrand, Reem Satti, Alison McDowall, Aure Aflalo, Andreas Neerincx, Jack Welland, et al.times with 1% Tween 20 in PBS and once with PBS, and then visualized using a Typhoon 5 Imager (CAT: 29187191, Cytiva Global Life Sciences Solutions Operations Ltd., Little Chalfont, Buckinghamshire, UK). In blotting

(2) Mechanisms of HIV Latency in Hematopoietic Progenitors: GFI1 as a Key RegulatorbioRxivFebruary 24, 2026Jackline A. Onyango, Chen Li, Cuie Chen, W Miguel Disbennett, Maria C. Virgilio, Mark M. Painter, Valeri H. Terry, Barkha Ramnani, Joshua D. Welch, Kathleen L. Collinsminutes at 100 V protected from light. Gels were imaged using an Amersham Typhoon 5 imager (Cytiva, cat#29187194). HEK293T co-transfections HEK293T cells were plated at 125,000 cells per well in 12-well plates and

(3) LOTUS: A low-cost time-lapse automated imaging system for spatio-temporal analysis of microbial colony or biofilm developmentPLOS OneJanuary 23, 2026Ryunosuke Sakai, Yifan Zhao, Martin RobertLB940 multimode microplate reader (Berthold Technologies GmbH & Co. KG, Bad Wildbad, Germany) and a Amersham Typhoon laser scanner (Cytiva, Marlborough, MA, USA) using serial dilutions of fluorescein sodium salt (Nacalai Tesque, Inc.,

(4) Pretargeted brain PET imaging reveals amyloid-β pathology using a TCO-modified antibody and a fluorine-18-labeled tetrazineTransl NeurodegenerDecember 26, 2025Sara Lopes van den Broek, Jonas Eriksson, Qiaojun Yang, Nadja M. Bucher, Eva Schlein, Lorenzo J. I. Balestri, Luke R. Odell, Dag Sehlin, Stina Syvänen28956477) for 2.5 h and the plate was scanned in an Amersham Typhoon IP phosphor imager (GE Healthcare, 29187194) at a resolution of 50 μm. To visualize the distribution of Aβ pathology, brain sections from separate

(5) Functional analyses of bacterial NanoRNase B proteins reveals defining features of this enzyme familyNucleic Acids ResDecember 11, 2025Tanner M Myers, Andrew A Burnim, Madison D Jermain, Holger Sondermann, Vincent T Lee, Xiaofang Jiang, Wade C Winklerresolved via denaturing 20% polyacrylamide gel electrophoresis (PAGE). Gels were imaged using a Cytiva Amersham Typhoon™ laser scanner platform. Gel quantification was conducted using FIJI software [32]. C-di-AMP cleavage assay NrnB-like

(6) Mechanistic insights into alcohol-induced DNA crosslink repair by Slx4-Xpf-Ercc1 nuclease complex in the Fanconi anaemia pathwayCommunications BiologySeptember 26, 2025Jana Havlikova, Milan Dejmek, Andrea Huskova, Anthony Allan, Evzen Boura, Radim Nencka, Jan Silhan0.01% bromophenol blue and analysed on 15% denaturing PAGE gel. The gels were visualised using the Amersham Typhoon laser scanner (Cytiva). The signals were analysed using ImageQuant TL version 8.2.0 software (Cytiva). The reaction

(7) An endogenous cluster of target-directed microRNA degradation sites induces decay of distinct microRNA familiesCell ReportsSeptember 23, 2025Nicholas M. Hiers, Lu Li, Tianqi Li, Peike Sheng, Yuzhi Wang, Conner M. Traugot, Michael Yao, Mingyi Xieagainst the desired RNAs for at least 6 h. IR signal was captured with an Amersham Typhoon (Cytiva, 29238583) and images were analyzed with ImageQuant TL (v7.0). RNA-seq library preparation Total RNA samples

(8) Nonenzymatic Primer Extension Experiments in the Presence of CoacervatesCurr ProtocJuly 24, 2025James D. Robinson, Derek K. O'Flaherty(Kimberly‐Clark, cat. no. 34120)Amersham Typhoon RGB biomolecular imager (GE Healthcare Life Sciences, cat. no. 29187193)ImageQuant software (GE Healthcare Life Sciences)Volocity visualization software (Volocity) Primer

(9) Polyglycine-mediated aggregation of FAM98B disrupts tRNA processing in GGC repeat disordersScienceJuly 17, 2025Jason Yang, Yunhan Xu, David R. Ziehr, Martin S. Taylor, Max L. Valenstein, Evgeni M. Frenkel, Jack R. Bush, Kate Rutter, Igor Stevanovski, Charlie Y. Shi, et al.minutes in 0.5% SDS/2X SSC at 42°C. Washed membranes were exposed to phosphor screens and imaged on an Amersham Typhoon laser scanner (Cytiva). Quantitation was performed by integrated density calculation in ImageJ and normalized as indicated

(10) Protocol for detecting SnRK2 kinase activity in plants by immunoblotting, in-gel assay, band shift, and immunoprecipitationSTAR ProtocolsJune 20, 2025Qingzhong Li, Xianping Yuan, Yang ZhaoERASER,Cytiva,29187190 Amersham Typhoon biomolecular imager,Cytiva,N/A Gel and blot imaging systems,Cytiva,29187194 Model 583 and HydroTech pump gel drying complete systems,Bio-Rad,165-1790 Round disposable Petri dishes

(11) Imaging poly(ADP-ribose) polymerase-1 (PARP1) in vivo with 18F-labeled brain penetrant positron emission tomography (PET) ligandActa Pharmaceutica Sinica BMay 26, 2025Xin Zhou, Jiahui Chen, Jimmy S. Patel, Wenqing Ran, Yinlong Li, Richard S. Van, Mostafa M.H. Ibrahim, Chunyu Zhao, Yabiao Gao, Jian Rong, et al.drawn with reference of naked-eye observation. Radioactivity was measured by an Amersham Typhoon 5 (29187191, GE Healthcare, NJ, USA) and normalized to % of radioactivity vs. control. The providers and catalog

(12) Parp3 assists muscle function and skeletal muscle differentiation by selectively adjusting H3K27me3 enrichmentiScienceApril 18, 2025Zuleyha Yildirim, Aurélia Noll, Kathline Martin-Hernandez, Jean-Christophe Amé, Najat Hanini, Nadia Messaddeq, Isabelle Robert, Bernardo Reina San Martin, Gunn Hildrestrand, Magnar Bjoras, et al.stained for 20 min with 50 μM TMRE added to the culture medium and fluorescence was captured using the Amersham Typhoon laser scanner (GE Healthcare). Cell extracts and western blotting For whole cell extracts, cells were lysed in cold

(13) Single-Molecule Fluorescence Visualization of DNA Polymerase Dynamics at G-QuadruplexesJournal of Visualized ExperimentsApril 4, 2025Nicholas Kusi-Appauh, Stefan H. Mueller, Stephen F. Ralph, Olga Yurieva, Michael E. O’Donnell, Jacob S. Lewis, Lisanne M. Spenkelinkrelevant wavelengths are let through to the detector Amersham Typhoon 5 biomolecular imager,Cytiva,29187191,Gel analysis Biotin-PEG-SVA (MW 5000),Laysan Bio,BIO-PEG-SVA-5K-100MG,Coverslip functionalization Deoxynucleotides

(14) VPS41 recruits biosynthetic LAMP-positive vesicles through interaction with Arl8bJ Cell BiolApril 3, 2025Paolo Sanzà, Jan van der Beek, Derk Draper, Cecilia de Heus, Tineke Veenendaal, Corlinda Ten Brink, Ginny G. Farías, Nalan Liv, Judith KlumpermanBlocking Buffer for 30 min. After another washing with TBS/0.1% Tween, membranes were imaged using Amersham Typhoon Laser Scanner (GE Healthcare Life Sciences). Plasmids To generate plasmids expressing mito-VPS41WT-V5, we PCR-ed

(15) Small molecule inhibitors of hnRNPA2B1-RNA interactions reveal a predictable sorting of RNA subsets into extracellular vesiclesNucleic Acids ResMarch 18, 2025Jessica Corsi, Pouriya Sharbatian Semnani, Daniele Peroni, Romina Belli, Alessia Morelli, Michelangelo Lassandro, Viktoryia Sidarovich, Valentina Adami, Chiara Valentini, Paolo Cavallerio, et al.additional 60 min. The RNA probe signal was detected using Typhoon Instrument (Amersham™ Typhoon™ 5-29187191) using filters for infrared emission detection. RNA immunoprecipitation Approximately 2 × 106 cells

(16) Multi-omic analysis of SDHB-deficient pheochromocytomas and paragangliomas identifies metastasis and treatment-related molecular profilesNat CommunMarch 17, 2025Aidan Flynn, Andrew D. Pattison, Shiva Balachander, Emma Boehm, Blake Bowen, Trisha Dwight, Fernando J. Rossello, Oliver Hofmann, Luciano Martelotto, Maia Zethoven, et al.three times in 0.5x SSC/0.1% SDS and exposed to a storage phosphor screen, which was imaged using an Amersham Typhoon laser scanner (Cytiva) and analysed by densitometry using ImageQuant software (Molecular Dynamics). C-Circle levels

(17) Phage parasites targeting phage homologous recombinases provide antiviral immunityNat CommunFebruary 22, 2025Gianluca Debiasi-Anders, Cuncun Qiao, Amrita Salim, Na Li, Ignacio Mir-Sanchis60–90 min (4 °C for Stl2, room temperature for SSB80α and Sak80α). The results were visualized with an Amersham Typhoon laser scanner (Cytiva) with the cy2 emission filter selected. Quantification of the bands of each gel was performed

(18) Generation, Propagation, and Titering of Dicistrovirus From an Infectious CloneBIO-PROTOCOLFebruary 20, 2025Junzhou Shen, Jibin Sadasivan, Eric JanFisher Scientific, catalog number: 2353-30-0010) 7. Typhoon biomolecular imager (Cytiva, catalog number: 29187191) Software and datasets 1. BioRender version 4.0 (BioRender.com, 10/2024) 2. HCS Navigator version

(19) Molecular basis of global promoter sensing and nucleosome capture by the SWR1 chromatin remodelerCellNovember 27, 2024Robert K. Louder, Giho Park, Ziyang Ye, Justin S. Cha, Anne M. Gardner, Qin Lei, Anand Ranjan, Eva Höllmüller, Florian Stengel, B. Franklin Pugh, et al.Inc.,N/A Superdex 75 Increase 10/300 GL,Cytiva,Cat #17517401 Typhoon biomolecular imager,Cytiva,Cat #29187191 SPARK 20M microplate reader,Tecan,N/A Orbitrap Fusion Tribrid mass spectrometer,Thermo Scientific,N/A Axio

(20) Protocol to study the direct binding of proteins to RNA:DNA hybrids or RNA-DNA chimeras in living cells using cross-linking immunoprecipitationSTAR ProtocolsSeptember 20, 2024Clara Bonnet, Ana Luisa Dian, Mélissa Leriche, Patricia Uguen, Stéphan Vagnercrosslinker, model 1800",Stratagene,Cat# 53267-1 Amersham Typhoon biomolecular imager,Cytiva,Cat# 29187191 Molecular Devices Image Eraser model 810-UNV,Molecular Dynamics,Cat# 19170 Exposure cassette 20 ×

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