HB-EGF ELISA DY259B from R&D Systems, a Bio-Techne Brand

Product Specs
ItemHB-EGF ELISA
CompanyR&D Systems, a Bio-Techne Brand
Price $890.00Supplier Page View Company Product Page
Catalog NumberDY259B
Quantity1 Kit (for 15 Plates)
ApplicationsELISA
Detection Range7.81 - 500 pg/mL
ReactivityHuman
Detection TargetHB-EGF
StorageStore the unopened product at 2 - 8 °C. Do not use past expiration date
NCBI Full Gene Nameheparin binding EGF like growth factor
NCBI Gene AliasesDTR, DTS, DTSF, HEGFL

Specifications/Features

Available conjugates: Sizes Available: 1 Kit (for 15 Plates)

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Interleukin-1β Stimulates Matrix Metalloproteinase 10 Secretion: A Possible Mechanism in Trophoblast-Dependent Spiral Artery RemodelingFASEB JMay 15, 2025Holly Tinsley, Zoe Tryfonos, Miriam Aziz, Nora Lagzouli, Charlotte Longhurst, Alexander Frick, Sandra Ashton, Judith E. Cartwright, Guy S. Whitleyvolume reached less than 200 μL. HB‐EGF was detected by ELISA using an HBEGF Duo Set (R&D Systems UK Cat#DY259B). To investigate the possible involvement of MMPs in the release of sHB‐EGF, cells were incubated in

(2) Interleukin‐1β Stimulates Matrix Metalloproteinase 10 Secretion: A Possible Mechanism in Trophoblast‐Dependent Spiral Artery RemodelingFASEB JMay 6, 2025Holly Tinsley, Zoe Tryfonos, Miriam Aziz, Nora Lagzouli, Charlotte Longhurst, Alexander Frick, Sandra Ashton, Judith E. Cartwright, Guy S. Whitleyvolume reached less than 200 μL. HB‐EGF was detected by ELISA using an HBEGF Duo Set (R&D Systems UK Cat#DY259B). To investigate the possible involvement of MMPs in the release of sHB‐EGF, cells were incubated in

(3) DNMT3A clonal hematopoiesis-driver mutations induce cardiac fibrosis by paracrine activation of fibroblastsNature communicationsJanuary 19, 2024Shumliakivska M, Luxán G, Hemmerling I, Scheller M, Li X, Müller-Tidow C, Schuhmacher B, Sun Z, Dendorfer A, Debes A, et al.

(4) Nectin-4 as Blood-Based Biomarker Enables Detection of Early Ovarian Cancer StagesCancers (Basel)November 29, 2022Christoph Rogmans, Julia Feuerborn, Leonie Treeck, Nils Tribian, Inken Flörkemeier, Norbert Arnold, Jörg Paul Weimer, Nicolai Maass, Peer Jansen, Wolfgang Lieb, et al.Duoset Sandwich Elisa (Nectin-4: R&D Systems, #DY2659/AREG: R&D Systems, #DY262/HB-EGF: R&D Systems, #DY259B, Minneapolis, MA, USA) ) was performed according to the modified test instructions. Testing was conducted

(5) ADAM17-A Potential Blood-Based Biomarker for Detection of Early-Stage Ovarian CancerCancersNovember 6, 2021Rogmans C, Kuhlmann JD, Hugendieck G, Link T, Arnold N, Weimer JP, Flörkemeier I, Rambow AC, Lieb W, Maass N, et al.instructions: Human Nectin-4 DuoSet ELISA (R&D Systems, #DY2659) and Human HB-EGF DuoSet ELISA (R&D Systems, #DY259B). The test was performed according to the instructions. 2.5. Cell Lyses, Westernblot and Densitometry In

(6) ADAM17 Inhibition Increases the Impact of Cisplatin Treatment in Ovarian Cancer SpheroidsCancersApril 23, 2021Hedemann N, Herz A, Schiepanski JH, Dittrich J, Sebens S, Dempfle A, Feuerborn J, Rogmans C, Tribian N, Flörkemeier I, et al.measured as a surrogate for ADAM17 activity. Therefore, the Human HB-EGF DuoSet ELISA (R&D Systems, #DY259B) was used according to the manufacturer’s instructions in NUNC-IMMUNO plates (Thermo Scientific, #442404,

(7) Airway Epithelial Cells Drive Airway Smooth Muscle Cell Phenotype Switching to the Proliferative and Pro-inflammatory PhenotypeFrontiers in physiologyJanuary 1, 2021O'Sullivan MJ, Jang JH, Panariti A, Bedrat A, Ijpma G, Lemos B, Park JA, Lauzon AM, Martin JG.

(8) ADAM17 Mediates Hypoxia-Induced Keratinocyte Migration via the p38/MAPK PathwayBioMed research internationalJanuary 1, 2021Zhu G, Liu J, Wang Y, Jia N, Wang W, Zhang J, Liang Y, Tian H, Zhang J.

(9) Efficient blockade of locally reciprocated tumor-macrophage signaling using a TAM-avid nanotherapyScience advancesMay 1, 2020Wang SJ, Li R, Ng TSC, Luthria G, Oudin MJ, Prytyskach M, Kohler RH, Weissleder R, Lauffenburger DA, Miller MA.

(10) Proximal Tubule-Derived Amphiregulin Amplifies and Integrates Profibrotic EGF Receptor Signals in Kidney FibrosisJournal of the American Society of Nephrology : JASNDecember 1, 2019Kefaloyianni E, Keerthi Raja MR, Schumacher J, Muthu ML, Krishnadoss V, Waikar SS, Herrlich A.was measured in human serum samples using microsphere-based Luminex Technology and ELISA kits (DY239, DY259B, and DY262, respectively; all from R&D Systems) as previously described.7,17 Statistical Analyses All

(11) EGFR-mediated matrix metalloproteinase-7 up-regulation promotes epithelial-mesenchymal transition via ERK1-AP1 axis during ovarian endometriosis progressionFASEB journal : official publication of the Federation of American Societies for Experimental BiologyAugust 1, 2018Chatterjee K, Jana S, DasMahapatra P, Swarnakar S.

(12) BK-UM in patients with recurrent ovarian cancer or peritoneal cancer: a first-in-human phase-I studyBMC cancerJanuary 31, 2017Miyamoto S, Yotsumoto F, Ueda T, Fukami T, Sanui A, Miyata K, Nam SO, Fukagawa S, Katsuta T, Maehara M, et al.

(13) ADAM17 substrate release in proximal tubule drives kidney fibrosisJCI insightAugust 18, 2016Kefaloyianni E, Muthu ML, Kaeppler J, Sun X, Sabbisetti V, Chalaris A, Rose-John S, Wong E, Sagi I, Waikar SS, et al.

(14) Fingolimod induces neuroprotective factors in human astrocytesJournal of neuroinflammationSeptember 30, 2015Hoffmann FS, Hofereiter J, Rübsamen H, Melms J, Schwarz S, Faber H, Weber P, Pütz B, Loleit V, Weber F, et al.

(15) The sorting protein PACS-2 promotes ErbB signalling by regulating recycling of the metalloproteinase ADAM17Nature communicationsJune 25, 2015Dombernowsky SL, Samsøe-Petersen J, Petersen CH, Instrell R, Hedegaard AM, Thomas L, Atkins KM, Auclair S, Albrechtsen R, Mygind KJ, et al.

(16) An EGFR wild type-EGFRvIII-HB-EGF feed-forward loop regulates the activation of EGFRvIIIOncogeneAugust 14, 2014Li L, Chakraborty S, Yang CR, Hatanpaa KJ, Cipher DJ, Puliyappadamba VT, Rehman A, Jiwani AJ, Mickey B, Madden C, et al.

(17) Anti-tumour effects of a specific anti-ADAM17 antibody in an ovarian cancer model in vivoPloS oneJanuary 1, 2012Richards FM, Tape CJ, Jodrell DI, Murphy G.

(18) Assessment of HB-EGF levels in peritoneal fluid and serum of ovarian cancer patients using ELISAAnticancer researchJuly 1, 2011Hikita S, Yotsumoto F, Fukami T, Horiuchi S, Sanui A, Miyata K, Nam SO, Tsujioka H, Ueda T, Shirota K, et al.

(19) The EGFR ligands amphiregulin and heparin-binding egf-like growth factor promote peritoneal carcinomatosis in CXCR4-expressing gastric cancerClinical cancer research : an official journal of the American Association for Cancer ResearchJune 1, 2011Yasumoto K, Yamada T, Kawashima A, Wang W, Li Q, Donev IS, Tacheuchi S, Mouri H, Yamashita K, Ohtsubo K, et al.

(20) Ectodomain shedding of EGFR ligands and TNFR1 dictates hepatocyte apoptosis during fulminant hepatitis in miceThe Journal of clinical investigationAugust 1, 2010Murthy A, Defamie V, Smookler DS, Di Grappa MA, Horiuchi K, Federici M, Sibilia M, Blobel CP, Khokha R.

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9/10/2018Very Helpful HB-EGF ELISA Kit for Human Samples Ashley WarrenBackground: Heparin-binding epidermal growth factor-like growth factor (HB-EGF) is a rational target for ovarian cancer therapy. The aim of this study was to examine HB-EGF levels in the peritoneal ... Read Review

HB-EGF ELISA

Human HB-EGF DuoSet ELISA

HB-EGF ELISA from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (25)

Reviews

HB-EGF ELISA from R&D Systems, a Bio-Techne Brand

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