Fig 1: Relationship between HO-1, LEDD and HY stage. Disease progression measured by H&Y scale progression. A) HO-1 protein levels of all non-PD controls (n=232) relative to PD cases subdivided into their h&Y stage (HY1 n=18, HY2 n=24, HY3 n=28) and B) HO-1 protein levels and c) LEDD levels among PD patients (n=70) subdivided into their H&Y stage. Statistical analyses were conducted with a=0.05, error bars indicate the mean with SEm. D) Linear regression analysis of LEDD and salivary HO-1 and Pearson correlation.
Fig 2: Salivary total protein and HO-1 levels between groups. A) Normal distribution visually assessed by Q-Q plot of salivary HO-1 protein level residuals and threshold 45°-line y=x B) Linear regression and correlation analyses between salivary HO-1 and total protein of study’s sample population. C) Unadjusted mean salivary total protein measured by BCA assay of non-neurological control group (n=162), degenrative neurological controls (n=37), and non-degenrative neurological controls(n=33) and PD group (n=75). Statistical analysis performed using ANOVA with a=0.05, error bars indicate the mean with SEM.
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