Fig 1: Olfactory and Taste Receptors expression on post-mortem OFC specimens from several Braak stages of sporadic AD compared to age-matched non-demented controls. a–e mRNA relative expression: a OR2K2. b OR2H2. c OR1L8 separated by sex. d TAS2R14. e TAS2R5 separated by sex. mRNA relative levels were normalized to GAPDH. f–j protein levels: f OR2K2. g OR2H2. h OR1L8 separated by sex. i TAS2R14. j TAS2R5 separated by sex. Error bars represent the standard error of the mean. Statistical significance is expressed as *P < 0.05, **P < 0.01, ***P < 0.001, and ****P < 0.0001 compared to age-matched non-demented controls (Braak stage 0), Kruskal–Wallis H test followed by Dunn's multiple comparisons post-hoc test. Sporadic AD samples, n = 49 and age-matched non-demented controls, n = 25