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CellTox Green Cytotoxicity Assay
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CellTox Green Cytotoxicity Assay
CellTox Green Cytotoxicity Assay
CellTox Green Cytotoxicity Assay from Promega
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Citations:
(102)
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CellTox Green Cytotoxicity Assay
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Description
The CellTox Green Cytotoxicity Assay measures changes in membrane integrity that occur as a result of cell death. The assay is intended to assess cytotoxicity in cell culture after experimental manipulation
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
CellTox Green Cytotoxicity Assay
Company
Promega
Price
$109.00
Supplier Page
View Company Product Page
Catalog Number
G8741
Quantity
10ml
Reactivity
mammal
Sample Type
cells in culture
Sensitivity
<200 cells="">200>
Assay Time
0-72 hours
Molecular Weight
~61kDa
Add to Compare List
Promega
2800 Woods Hollow Rd
Madison
,
WI
53711
United States
Phone
: Tel: +1 (608) 274-4330
Fax: +1 (608) 277-2516
Email: custserv@promega.com
techserv@promega.com
Company Profile
Website:
http://www.promega.com
Citations (102)
(1)
Adaptor protein supersaturation drives innate immune signaling and cell fate
eLife
March 24, 2026
Alejandro Rodriguez Rodriguez Gama, Tayla Miller, Shriram Venkatesan, Jeffrey J Lange, Jianzheng Wu, Xiaoqing Song, William D Bradford, Malcolm Cook, Jay R Unruh, Randal Halfmann
(
BioVision
,
1544–5
), Puromycin (
Invivogen
,
ant-pr-1
), Sytox
Orange
(
Thermo Fisher
,
S11368
), CellTox (
Promega
,
G8741
), Annexin V Alexa568 (
1:200
,
Thermo Fisher
,
A13202
), Annexin V Alexa488 (
1:200
,
Thermo Fisher
,
A13201
),
(2)
Protocol for generating an in vitro 3D multicellular culture model of ovarian high-grade serous carcinoma
STAR Protocols
March 20, 2026
Krister Wennerberg, Daria Bulanova, Laura Gall-Mas, Wojciech Senkowski, Lidia Moyano-Galceran
assays
,Critical commercial
assays
,Critical commercial
assays
,,
CellTox Green Cytotoxicity Assay
,
Promega
,Cat#
G8741
CellTiter-Glo 2.0
Cell Viability Assay
,Promega,Cat# G9421 ,,
Experimental models
: Cell lines,
Experimental models
(3)
Photochemical enhancement of PD-L1-SAP immunotoxin efficacy in non-small cell lung cancer cell lines
Front Immunol
March 13, 2026
Magdaléna Kozlíková, Inger Kristine Fjeldskaar Aukrust, Monika Rohlíčková, Miloslav Macháček, Kristian Berg, Anette Weyergang, Pål Kristian Selbo
distinguish dead cells, cells were stained with
CellTox™ Green Cytotoxicity Assay
(
Promega
, USA, cat. no.
G8741
) at a dilution of
1: 6000
. The following controls were included: Unstained cells; cells stained with
(4)
Modulation of islet amyloid polypeptide induced β-cell toxicity and amyloid formation by serum albumin proteins
Biophysical Chemistry
March 1, 2026
Alexander Zhyvoloup, Zachary Ridgway, Ananya Prashanth, Daniel P. Raleigh
#
16250078
) and 50 μM β-mercaptoethanol. CellTiter-Glo 2.0 (
Promega
, #
G9242
) and CellTox Green (
Promega
, #
G8741
)
assays
were used to evaluate the cytotoxicity of hIAPP towards INS-1 β-cells. SA stocks were prepared
(5)
Temporal dynamics of collateral RNA cleavage by LbuCas13a in human cells
Communications Biology
January 19, 2026
Jorik Frederik Bot, Zhihan Zhao, Mengyuan Li, Darnell Kammeron, Peng Shang, Niels Geijsen
imaging medium (FluoroBrite™ DMEM, 10% FBS, 2.5 mM CaCl2) supplemented with 2 µL CellTox™ Green (
Promega
,
G8741
) and 5 µL Annexin V-AV647 (
Invitrogen
,
A23204
) per milliliter. Cells were seeded in 8-well µ-Slides
(6)
Unbiased combination screening on repurposed drugs reveals synergistic potential of copanlisib and cerivastatin against chemoresistant high-grade serous ovarian cancer
Journal of Ovarian Research
November 6, 2025
Yu Sun, Yangyang Wang, Syed Umbreen, Benjamin Pepperrell, Niamh Buckley, Paul Mullan, Ahlam Ali, Fiona Furlong
cell viability
assays
Cytotoxicity was assessed using the CellTox Green Cytotoxicity Kit (
Promega
#
G8741
). CellTox Green dye was added to 384-well black optical bottom plates (Greiner CELLSTAR#M1937) at a
(7)
PNKP targeting engages the autophagic machinery through STING and STAT3 to potentiate ferroptosis and chemotherapy in TNBC
Redox Biology
October 1, 2025
Avi Maimon, Pier Giorgio Puzzovio, Yaron Vinik, Gavriel-David Hannuna, Sara Donzelli, Daniela Rutigliano, Giovanni Blandino, Sima Lev
performed using the drc package in R. Cell death was measured by the
CellTox-green Cytotoxicity assay
(
G8741
,
Promega
) according to the manufacturer instructions. In brief, cells were seeded in 96 wells black
(8)
Differential Effects of Selenium Compounds on Mitochondrial Function in PRRSV-Infected Porcine Alveolar Macrophages
Viruses
September 26, 2025
Abigail Williams, Christina Bourne, John Byrne, Chaitawat Sirisereewan, Brittany M. Pecoraro, Elisa Crisci
integrity using the CellToxTM Green Cytotoxicity Assay kit following the endpoint Method (Catalog No.
G8741
,
Promega
, Madison, WI, USA). This
assay
quantifies the fluorescent signal proportional to the asymmetric
(9)
New insights into the 17β-hydroxysteroid dehydrogenase type 10 and amyloid-β 42 derived cytotoxicity relevant to Alzheimer's disease
Alzheimers Res Ther
July 23, 2025
Aneta Houfková, Monika Schmidt, Ondřej Benek, Ivo Fabrik, Rudolf Andrýs, Lucie Zemanová, Ondřej Soukup, Kamil Musílek
CellTiter-Glo Luminescent Cell Viability Assay
and
CellTox Green Cytotoxicity Assay
kits (
Promega
, G7574 and
G8741
), respectively.
For multiplex
measurement, 5 × 103 cells were seeded in 50 µL of glucose or galactose
(10)
Circadian synchronization differentially modifies cytokine-mediated transcriptomic remodeling and cell death in INS-1 cells and mouse islets
iScience
May 16, 2025
Phillip Alexander Keller Andersen, Rasmus H. Reeh, Isabel Sanders, Emilie Bender Overlund, Georgia Katsioudi, Cecilia Jiménez-Sánchez, Emil Zeng Skovhøj, Anniek Frederike Lubberding, Charna Dibner, Thomas Mandrup-Poulsen
G8200
Caspase-Glo™ 9 Assay
System,
Promega
,Cat#
G8210
CellTox™ Green Cytotoxicity Assay
,
Promega
,Cat#
G8741
iScript™ cDNA Synthesis Kit
,
Bio-Rad Laboratories
,Cat#
1708891
NucleoSpin® RNA
,
Macherey-Nagel
,Cat#
(11)
JAK inhibitors remove innate immune barriers facilitating viral propagation
NAR Molecular Medicine
May 2, 2025
Erlend Ravlo, Aleksandr Ianevski, Marius Nårstad Skipperstøen, Hilde Lysvand, Jørn-Ove Schjølberg, Ole Solheim, Wei Wang, Miroslava Kissova, Marthe Vestvik, Olli Vapalahti,
et al.
assessed using the CellTiter-Glo (CTG) and CellTox Green (CTxG)
assays
(
Promega
, Cat. nos.
G9241
and
G8741
, respectively). Measurements were performed on a
FluoStar Omega
plate reader (
BMG Labtech
), followed
(12)
Targeting metabolic vulnerability by combining NAMPT inhibitors and disulfiram for treatment of recurrent ovarian cancer
Cell Death Dis
April 25, 2025
Kei Kudo, Yoshimi Endo Greer, Daniel R. Crooks, Ye Yang, Jeffrey R. Brender, Teruhiko Yoshida, Brittney S. Harrington, Rahul Kamdar, Soumya Korrapati, Yusuke Shibuya,
et al.
used to assess the total number of viable cells. To
measure
the cytotoxicity, CellTox Green
assay
(#
G8741
,
Promega
) was used. Data were normalized to the median value of control wells and analyzed using the
(13)
Hyperglycemia-induced DNA damage response activates DNA-PK complex to promote endothelial ferroptosis in type 2 diabetic cardiomyopathy
Theranostics
March 19, 2025
Cheng Luo, Chen Fang, Rongjun Zou, Jingwei Jiang, Miao Zhang, Teng Ge, Hao Zhou, Xiaoping Fan, Baoshi Zheng, Zhiyu Zeng
caspase activity
assays
To evaluate the cytotoxic effects of high glucose on CMECs, CellToxGreen (
G8741
;
Promega
) and RealTime-Glo™ MT Cell Viability (
G9711
;
Promega
)
assays
were employed, following the manufacturer's
(14)
Investigating synthetic lethality and PARP inhibitor resistance in pancreatic cancer through enantiomer differential activity
Cell Death Discov
March 16, 2025
Mirco Masi, Laura Poppi, Viola Previtali, Shannon R. Nelson, Kieran Wynne, Giulia Varignani, Federico Falchi, Marina Veronesi, Ennio Albanesi, Daniele Tedesco,
et al.
treatment sample. Cytotoxicity assay Cell death was assessed using the
CellTox Green cytotoxicity assay
(#
G8741
,
Promega
) as described in [14]. BxPC-3 cells (104 cells/well) were seeded in a clear-bottom black 96-multiwell
(15)
Methamphetamine-mediated astrocytic pyroptosis and neuroinflammation involves miR-152–NLRP6 inflammasome signaling axis
Redox Biology
March 1, 2025
Abiola Oladapo, Muthukumar Kannan, Uma Maheswari Deshetty, Seema Singh, Shilpa Buch, Palsamy Periyasamy
methamphetamine + Disulfiram. Cell death was measured using the
CellTox™ Green Cytotoxicity Assay
(Cat No.
G8741
,
Promega
, Madison, WI, USA) according to the manufacturer's protocol. The 24-well
cell culture
plate
(16)
The integrated stress response regulates 18S nonfunctional rRNA decay in mammals
Molecular Cell
February 20, 2025
Aaztli R. Coria, Akruti Shah, Mohammad Shafieinouri, Sarah J. Taylor, Emilien Orgebin, Wilfried Guiblet, Jennifer T. Miller, Indra Mani Sharma, Colin Chih-Chien Wu
assays
,Critical commercial
assays
,Critical commercial
assays
CellTox Green Cytotoxicity,
Promega
,Cat#
G8741
Deposited data,Deposited data,Deposited data GEO,This paper,GSE255784 SRA,This paper,PRJNA1195343 MassIVE,This
(17)
Pharmacological CDK4/6 inhibition promotes vulnerability to lysosomotropic agents in breast cancer
The EMBO Journal
February 10, 2025
Jamil Nehme, Sjors Maassen, Sara Bravaccini, Michele Zanoni, Caterina Gianni, Ugo De Giorgi, Abel Soto-Gamez, Abdullah Altulea, Teodora Gheorghe, Boshi Wang,
et al.
inhibitor),
Cayman Chemical
,
13355
Vacuolin-1
,
MedChemExpress
,
HY-118630
CellTox™ Green Cytotoxicity Assay
,
Promega
,
G8741
CellTiter 96® Aqueous Non-Radiative Cell Proliferation Assay,
Promega
,
G5421
Acridine orange
,
Sigma-Aldrich
,235474
CytoFix™ Red Lysosomal Stain
(18)
Mapping chromatin remodelling in glioblastoma identifies epigenetic regulation of key molecular pathways and novel druggable targets
BMC Biol
February 7, 2025
Claire Vinel, James Boot, Weiwei Jin, Nicola Pomella, Alexandra Hadaway, Charles Mein, Nicolae Radu Zabet, Silvia Marino
CellTiter-Glo Luminescent Cell Viability Assay
with
CellTox Green Cytotoxicity Assay
(
Promega
kits
G7570
and
G8741
). Wound healing migration
assay
5 × 104 cells of GIC were seeded per well in a 96-well plate coated
(19)
How NINJ1 mediates plasma membrane rupture and why NINJ2 cannot
Cell
January 23, 2025
Bibekananda Sahoo, Zongjun Mou, Wei Liu, George Dubyak, Xinghong Dai
Assembly HiFi Master Mix,Invitrogen™,Cat #: A46627
CellTox™ Green Cytotoxicity Assay
,
Promega
,Cat #:
G8741
Deposited data,Deposited data,Deposited data
Cryo-EM
map of the
human
NINJ1 wild type (WT) filament,This
(20)
Synergistic combination of orally available safe-in-man pleconaril, AG7404, and mindeudesivir inhibits enterovirus infections in human cell and organoid cultures
Cell Mol Life Sci
January 23, 2025
Erlend Ravlo, Aleksandr Ianevski, Jørn-Ove Schjølberg, Vanessa Solvang, Rabina Dumaru, Hilde Lysvand, Jacqueline Hankinson, Markus Vähä-Koskela, Sanna Vainionpää, Anni Varhe,
et al.
Alamar blue (
Invitrogen
,
DAL1100
,
1:10
dilution in AEM), and CellToxGreen
assays
(CTxG;
Promega
#
G9241
,
G8741
). Measurments of glucose and
human
insulin levels Accu-Chek Mobile Blood Glucometer with test cassettes
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CellTox Green Cytotoxicity Assay from Promega
Supplier Page
View Company Product Page
$109.00
Product Specs
Company Info
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