Description
High-fidelity, low-bias library amplification that delivers excellent fidelity, uniform sequence coverage, and high library complexity to specifically address the stringent demands of applications such as rare variant detection, circulating cell-free DNA (cfDNA) analysis, single-cell analysis, and hybridization capture. Kits contain a uniquely engineered, ultra-high fidelity DNA polymerase in an optimized hot start PCR mix.
- Increase overall assay sensitivity with ultra-high-fidelity amplification, reducing misincorporation events by up to 40%
- Improve sequencing economy with highly uniform sequence coverage
- Amplify libraries efficiently from a wide range of inputs (0.1 pg – 500 ng) and GC content (15% to 85%)
- Enable low-input applications and automated workflows with a highly effective antibody-based hot start formulation
- Compatibility with paramagnetic beads delivers robust performance in hybridization capture workflows