Fig 1: Role of CD10 in BCM-induced lymphocyte changes in mouse DSS colitis model. (A–K) Lymphocytes markers and other factors were examined in mucosal proteins using ELISA. (A) CD11b (neutrophils). (B) CD68 (macrophages). (C) 4HNE (oxidative stress). (D) CD45RO (common lymphocytes). (E) CD3. (F) CD20. (G) CD4. (H) CD8. (I) FOXP3 (regulatory T). (J) IFNγ. (K) Granzyme B. (L–O) Mucosal CD8 + IFNγ+ cells analyzed by flow cytometry. Error bars indicate standard deviation from 5 mice. Statistical differences were calculated by ANOVA with Bonferroni correction. BCM, β-casomorphin-7; C, control; TOP, thiorphan; DSS, dextran sulfate sodium; FOXP3, forkhead box P3; 4HNE, 4-hydroxynonenal; IFNγ, interferon-γ.
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