Fig 1: Salivary biomarker concentrations between the different groups of horses: No EGUS (n = 22), EGUS non-clinical (n = 28) and EGUS clinical (n = 28). Mean levels of IL1-F5 (a), PIP (b), CA-VI (c), serotransferrin (d), and albumin (e), where the error bars represent the standard deviation (SD). The p-value is indicated in all comparisons, and the effect size (Cohen d) only when there were statistically significant differences.
Fig 2: Salivary biomarker concentrations between the different groups of horses: No EGUS (n = 22) and EGUS clinical subdivided into ESGD (n = 9), EGGD (n = 8) and ESGD + EGGD (n = 11). Mean levels of IL1-F5 (a), PIP (b), CA-VI (c), serotransferrin (d), and albumin (e), where the error bars represent the standard deviation (SD). The p-value is indicated when there were statistically significant differences.
Fig 3: ROC curves and cut-offs of IL1-F5 (a), PIP (b), CA-VI (c), serotransferrin (d), and albumin (e), between the No EGUS horses and the EGUS clinical horses. The x-axis represents the % of specificity, and the y-axis the % of sensitivity. The cut-off points represent the value with the best pair sensitivity-specificity.
Fig 4: Linear regression lines indicating the accuracy of the assays used for measuring each biomarker in serial dilution of two saliva samples with different concentrations of proteins. The slopes of the regression lines are indicated for each serial dilution. (a) IL1-F5, (b) PIP, (c) CA-VI, (d) serotransferrin, and (e) albumin.
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