Fig 1: Network meta-analysis on association between the gut microbiota and immune markers by sex. (A) Network meta-analysis results for the delta values of variables by sex. The thickness of the solid line indicates the strength of association. Blue and red colors of the solid line indicate the positive and negative correlation, respectively. Node with red colors indicates significant results. (B) Spearman’s rank correlation analysis between the rank of variables by sex.CRP, C-reactive protein; DC, dendritic cell; LBP, lipopolysaccharide-binding protein.
Fig 2: LBP and VEGF protein levels in DME and their correlations with CST. A: Relative abundance of LBP protein as determined by proteomic analysis using mass spectrometry expressed in log2-transformed label-free quantification units (LFQ), and LBP and VEGF log10-transformed concentrations as determined by ELISA. B: Correlation between LBP and VEGF concentrations, correlation between LBP proteomics data and CST, and correlation between LBP protein concentrations of ELISA and CST. A best-fit linear regression line with 95% confidence bands (dotted line) is shown. Pearson’s correlation coefficient (r) and p values (P) are given, with p < 0.05 being statistically significant.
Fig 3: Receiver operating characteristic (ROC) curves for admission biomarkers and biomarker panels in predicting nosocomial infection in cirrhotic patients with upper gastrointestinal bleeding. (A) Individual biomarkers. ROC curves for selected admission biomarkers showing discriminative performance for nosocomial infection. (B) Comparison of ROC curves for three admission‐time biomarker models: The prespecified index panel LBP + PCT + lactate, the pragmatic explanatory model LBP + CRP + albumin derived from multivariable analysis, and a routine inflammatory benchmark model (WBC + CRP). Alb, albumin; AUC, area under the curve; CRP, C‐reactive protein; INR, international normalized ratio; LBP, lipopolysaccharide‐binding protein; LMR, lymphocyte‐to‐monocyte ratio; Na, sodium; NLR, neutrophil‐to‐lymphocyte ratio; PCT, procalcitonin; PLR, platelet‐to‐lymphocyte ratio; TB, total bilirubin; WBC, white blood cells.
Fig 4: Pairwise correlations among candidate predictors at admission. Heatmap of pairwise Spearman correlation coefficients (ρ) among candidate predictors measured at admission. Correlations were modest overall, with all |ρ| < 0.60, indicating limited linear/monotonic association between variables. Alb, albumin; ALT, alanine aminotransferase; AST, aspartate aminotransferase; CRP, C‐reactive protein; ESR, erythrocyte sedimentation rate; Hb, hemoglobin; INR, international normalized ratio; LBP, lipopolysaccharide‐binding protein; LMR, lymphocyte‐to‐monocyte ratio; Na, sodium; NLR, neutrophil‐to‐lymphocyte ratio; NMR, neutrophil‐to‐monocyte ratio; PCT, procalcitonin; PLR, platelet‐to‐lymphocyte ratio; PLT, platelet count; TB, total bilirubin; WBC, white blood cells.
Supplier Page from Abcam for Human LBP ELISA Kit (LPS Binding Protein)