TUNEL In Situ Apoptosis Kit (HRP-DAB Method) E-CK-A331 from Elabscience Bionovation Inc.

Product Specs
ItemTUNEL In Situ Apoptosis Kit (HRP-DAB Method)
CompanyElabscience Bionovation Inc.
Price $780.00Supplier Page View Company Product Page
Catalog NumberE-CK-A331
StorageThis product can be stored at -20°C for 12 months with shading light
Quantity100 Assays
Sample TypeParaffin section;frozen section;cell slide
Assay Time3 hours
DetectionColorimetric method

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Elabscience Bionovation Inc.

14780 Memorial Drive

Suite 105

Houston, Texas 77079

United States

Phone: 1-832-243-6086
Toll-free: 1-888-852-8623
Fax: 1-832-243-6017

Email: techsupport@elabscience.com

Company Profile

Website: www.elabscience.com

(1) Investigation of Protective Effects of Carvacrol and Hesperidin in Rats with Streptozotocin-Induced Diabetic NephropathyLife (Basel)June 26, 2026Nilüfer Kuruca, Tolga Güvençusing a commercial TUNEL Apoptosis Detection Kit (HRP–DAB) (Elabscience, Houston, TX, USA, Cat. No. E-CK-A331) according to the manufacturer’s protocol. Briefly, paraffin sections were deparaffinized, rehydrated,

(2) Limonin alleviates pyroptosis and inflammatory responses in cardiomyocytes of myocardial ischemia-reperfusion mice by inhibiting the caspase-3/GSDME pathwayFrontiers in ImmunologyApril 29, 2026Jianlong Li, Zhe Li, Pengran Wang, Zhian Jianglabeling staining Apoptotic cells in myocardial tissue sections were detected using a TUNEL assay kit (E-CK-A331; Wuhan Elabscience Biotechnology Co. Ltd, Wuhan, China) according to the manufacturer’s instructions.

(3) BNIP3/BNIP3L-Dependent Mitophagy Protects Against Hippocampal Neuronal Damage and Apoptosis in a Model of Vascular DementiaCellsMarch 25, 2026Yujiao Wang, Daojun Xie, Shijia Ma, Yuhe Wang, Chengcheng Zhang, Zhuyue ChenStaining Apoptotic cells were detected using a commercial TUNEL Apoptosis Assay Kit (Elabscience, E-CK-A331, Wuhan, China). Following dewaxing, tissue sections were treated with proteinase K and incubated with

(4) IGFBP3 repression driven by inflammation links air pollution to placental and developmental defectsEMBO Molecular MedicineMarch 24, 2026Sunil Singh, Isha Goel, Anubhuti Rana, Anamta Gul, Javed A Quadri, Asit Ranjan Mridha, Lakshay Malhotra, Neha Kashyap, Baburajan Radha, Arnab Nayek, et al.with Rat placental tissue section using Elabscience® TUNEL In Situ Apoptosis Kit (HRP-DAB Method) (E-CK-A331) following manufacturer protocol. Results were quantified using imageJ. Iron detection in paraffin-embedded tissue

(5) Repurposing metformin as a dual-function agent to combat E. coli-induced mastitis: Mechanistic insights into biofilm dispersion and AMPK/SIRT1-mediated NF-κB inhibitionPLoS PathogMarch 6, 2026Tianle Xu, Wendi Cao, Shuangyuan Fan, Run Liu, Hao Zhu, Xubin Lu, Zhipeng Zhang, Xiaojiao He, Kai Zhang, Jie Huang, et al.cells in sections of sheep mammary tissue were detected using the TUNEL In Situ Apoptosis Kit (HRP-DAB, E-CK-A331, Elabscience, China). Following deparaffinization and proteinase K treatment, the sections were incubated

(6) Silencing of Cholesterol 25‐Hydroxylase Attenuates Lipopolysaccharide‐Induced Cardiomyocyte Damage In VitroJournal of Cellular and Molecular MedicineNovember 26, 2025Yi‐jiao Men, Hong‐bo Cheng, Yan‐ling Dong, Yu Gong, Ya‐qing An, Ying‐li Jin, Shu‐na Hao, Yu Ma, Ying‐ping Tianusing a TUNEL In Situ Apoptosis Kit (Horseradish peroxidase‐3,3′‐Diaminobenzidine [HRP‐DAB] Method; E‐CK‐A331, Elabscience, Wuhan, China) according to the manufacturer's instructions. 2.5 ELISA and Mitochondrial

(7) Unfolded protein response kinase PERK supports survival and metastasis of circulating tumor cell clusters via SAM synthesis and H3K4me3‐dependent PDGFB signalingCancer CommunicationsNovember 10, 2025Rui Tang, Yan Sun, Ao Deng, Jiahe Liu, Peijin Dai, Jing Chen, Chaoqun Deng, Hui Liu, Yuhang Hai, Yanran Tong, et al.(Olympus Corporation, Tokyo, Japan). For TUNEL staining, IHC was performed using a TUNEL assay kit (E‐CK‐A331, Elabscience). Lung tissue sections were incubated with the TUNEL reagent following the manufacturer's

(8) Long-Term Maternal Exposure to Triclosan Provokes Pulmonary Fibrosis in Mouse OffspringEnviron Health (Wash)October 17, 2025Jing Liu, Mingzhu Guo, Wenqing Li, Bingwei Yang, Yang SongChina); TSA Fluorescence Double Staining Kit (G1235, Servicebio, China); TUNEL Apoptosis Assay Kit (E-CK-A331, Elabscience, China); TRNzol Universal Reagent (DP424, TIANGEN, China); PrimeScript RT reagent Kit (RR037A,

(9) Levosimendan Pretreatment Attenuates Mesenteric Artery Ischemia/Reperfusion Injury and Multi-Organ Damage in RatsInternational Journal of Molecular SciencesSeptember 18, 2025Zoran Matković, Milica Gajić Bojić, Uglješa Maličević, Aleksandra Krivokuća, Nebojša Mandić-Kovačević, Snežana Uletilović, Ljiljana Amidžić, Sanja Jovičić, Maja Barudžija, Miloš P. Stojiljković, et al.using a commercial TUNEL detection kit (TUNEL In Situ Kit, Elabscience, Wuhan, China; catalogue number: E-CK-A331) according to the manufacturer’s instructions. Briefly, paraffin sections were deparaffinised, rehydrated,

(10) Adaptive loss of shortwave-sensitive opsins during cartilaginous fish evolutionNat CommunAugust 18, 2025Bo Zhang, Yidong Feng, Meiqi Lv, Lei Jia, Yongguan Liao, Xiaoyan Xu, Axel Meyer, Jinsheng Sun, Guangyi Fan, Yumin Li, et al.were recorded with a pathology slide scanner (SP8, Leica, Germany). TUNEL staining TUNEL assay kit (E-CK-A331, Elabscience, US) and TMB chromogenic (322550, ACD, US) were performed for TUNEL staining according

(11) Compound K-enriched Korean red ginseng prevents lung cancer progression by targeting cancer cells and fibroblastsJournal of ginseng researchJuly 1, 2025Hwang JH, Park SY, Kang JH, Jung HJ, Park J, Maeng HJ, Choi MK, Song HS, Song IS, Oh SH.transferase-mediated dUTP nick-end labeling staining) with an apoptotic cell detection kit (HRP-DAB, Elabscience, E-CK-A331) [56]. 2.18 Statistical analysis The data acquired in this study were presented as mean ± standard

(12) CKAP5 deficiency induces premature ovarian insufficiencyEBioMedicineApril 18, 2025Zihao Hu, Jingping Gao, Panpan Long, Ruping Quan, Fei Huang, Jixuan Jiang, Jing Zhang, Jianlin Chen, Hongmei Xiao, Hualin Huangsections were deparaffinized. The TUNEL assay was conducted according to the manufacturer’s protocol (E-CK-A331, Elabscience). Ethics statement The animal study was reviewed and approved by the ACUC of Hunan University

(13) Multifaceted Cardioprotective Potential of Reduced Glutathione Against Doxorubicin-Induced Cardiotoxicity via Modulating Inflammation–Oxidative Stress AxisInternational Journal of Molecular SciencesMarch 30, 2025Amr Negm, Ezat A. Mersal, Amal F. Dawood, Amira O. Abd El-Azim, Omar Hasan, Rayan Alaqidi, Ahmed Alotaibi, Mohammed Alshahrani, Abdullah Alheraiz, Tamer M. Shawkystaining was performed to detect in situ DNA fragmentation using the in-situ Apoptosis Detection Kit (E-CK-A331, Elabscience, Wuhan, China), using a fluorescence microscope (Olympus DX51, Tokyo, Japan) [75]. The

(14) Adropin ameliorates reproductive dysfunctions in letrozole-induced PCOS mouseSci RepMarch 13, 2025Shweta Maurya, Shashank Tripathi, Taruna Arora, Ajit Singhassessed by in situ 3´-OH end labeling of broken DNA fragments using the TUNEL apoptosis kit (catalog no: E-CK-A331, Elabscience Biotechnology Inc., Texas, USA). The paraffin-embedded ovarian histological sections of

(15) Propionic acid mediates the renoprotective effects of fecal microbiota transplantation against ischemia-reperfusion injury via upregulating GPR43Frontiers in cellular and infection microbiologyJanuary 1, 2025Yu J, Liu Z, Wang Y, Zhou Y, Liu W, Wang T, Xie Q, Tian H, Xu Y, Wang M, et al.China",Cat. no. BS-E12215R2 TUNEL in situ apoptosis kit (HRP-DAB method),"Elabscience, Wuhan, China",E-CK-A331 Experimental models: organisms/strains,Experimental models: organisms/strains,Experimental models:

(16) Effect of Petiveria alliacea leaf extract and its active components on heart muscle cell apoptosis induced by hyperglycemiaOpen Vet JNovember 30, 2024Nurmawati Fatimah, Sri Agus Sudjarwo, Arifa Mustika, Suharjono Suharjono, Jusak Nugraha, Hari Basuki Notobroto, Rochmah Kurnijasanti, Reny I’tishom, Wibi Riawan, Alphania Rahniayuimmunohistochemistry (IHC) staining (Bioenzy® kit), for Bcl2 (monoclonal AB, Santacruz) and apoptosis (E-CK-A331, Elabscience). Counterstaining was then conducted using methyl green, followed by the mounting process.

(17) Effect of Petiveria alliacea leaf extract and its active components on heart muscle cell apoptosis induced by hyperglycemiaOpen Veterinary JournalNovember 30, 2024Nurmawati Fatimah, Sri Agus Sudjarwo, Arifa Mustika, Suharjono Suharjono, Jusak Nugraha, Hari Basuki Notobroto, Rochmah Kurnijasanti, Reny I'tishom, Wibi Riawan, Alphania Rahniayuimmunohistochemistry (IHC) staining (Bioenzy® kit), for Bcl2 (monoclonal AB, Santacruz) and apoptosis (E-CK-A331, Elabscience). Counterstaining was then conducted using methyl green, followed by the mounting process.

(18) LncRNA FAISL Inhibits Calpain 2‐Mediated Proteolysis of FAK to Promote Progression and Metastasis of Triple Negative Breast CancerAdvanced ScienceNovember 1, 2024Yunmei Zhang, Shiyu Wei, Zhengjie Chen, Rui Xu, Shu‐Rong Li, Lili You, Ruiyue Wu, Yin Zhang, Jian‐You Liao, Xiaoding Xu, et al.(high). TUNEL Assay The assay was performed following the manufacturer's protocol of the TUNEL kit (E‐CK‐A331, Elabscience, Wuhan, China). Paraffin‐embedded tissues slides were treated with 1× protease K for 30

(19) Epithelial CEBPD activates fibronectin and enhances macrophage adhesion in renal ischemia-reperfusion injuryCell death discoveryJuly 18, 2024Chang SS, Cheng CC, Chen YR, Chen FW, Cheng YM, Wang JM.instructions of the terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) assay kit (# E-CK-A331, Elabscience company, USA). Fluorescence images were taken by fluorescence microscopy (BX51, Olympus).

(20) Semaglutide attenuates doxorubicin-induced cardiotoxicity by ameliorating BNIP3-Mediated mitochondrial dysfunctionRedox BiologyJune 1, 2024Xiaoping Li, Wenbin Luo, Yang Tang, Jiangjiao Wu, Junkai Zhang, Shengnan Chen, Lu Zhou, Yu Tao, Yuanjuan Tang, Fengxian Wang, et al.Bioscience). 2.8 TUNEL staining TUNEL staining of heart slices used a one-step TUNEL In Situ Apoptosis Kit (E-CK-A331, Elabscience, Wuhan, China). Images were obtained using Olympus SlideView VS200 microscope. 2.9 Immunofluorescence

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TUNEL In Situ Apoptosis Kit (HRP-DAB Method)

TUNEL In Situ Apoptosis Kit (HRP-DAB Method) from Elabscience Bionovation Inc.

Elabscience Bionovation Inc.

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TUNEL In Situ Apoptosis Kit (HRP-DAB Method) from Elabscience Bionovation Inc.

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