Fig 1: Effect of ADMSCs-derived exosomes on DOX/Trz-induced cardiac DNA damage and apoptosis: (A) Topoisomerase 2 beta (Top2b) and (B) p53 concentration by ELISA. Results are expressed as mean ± SEM; and (C) mRNA levels of cardiac Bax, Bcl-2, Bax/Bcl2 ratio, and PUMA. Data are expressed as median (maximum, minimum). *, significant compared to Group I at p ? 0.05; **, significant compared to Group I at p ? 0.01; ***, significant compared to Group I at p ? 0.001; #, significant compared to Group II at p ? 0.05; ##, significant compared to Group II at p ? 0.01; $, significant compared to Group III at p ? 0.05; n = 6.
Supplier Page from Thermo Fisher Scientific for Rat p53 ELISA Kit