VEGFR2 (KDR) Kinase Assay Kit 40325 from BPS Bioscience, Inc.

Product Specs
ItemVEGFR2 (KDR) Kinase Assay Kit
CompanyBPS Bioscience, Inc.
Price $560.00Supplier Page View Company Product Page
Catalog Number40325
Quantity96 reactions
TypeAssay Kit
ApplicationsUseful for studying enzyme kinetics and screening small molecular inhibitors for drug discovery and HTS applications

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BPS Bioscience, Inc.

6405 Mira Mesa Blvd

Suite 100

San Diego, CA 92121

United States

Phone: 858-202-1401

Email: sales-team@bpsbioscience.com

Company Profile

Website: https://bpsbioscience.com/

(1) Ferulic and p-coumaric acid derivatives as dual EGFR-VEGFR2 inhibitors: design, semi-synthesis, and biological investigationsRSC AdvApril 8, 2026Ranza Elrayess, Mohamed S. Nafie, Safwat A. Ahmed, Yosra K. Alkazzaz, Khaled M. Darwish, Heba N. Gad El-Hak, Enas E. EltamanyCorporation Catalog #40321) and VEGFR-2 kinase inhibition using (BPS Bioscience Corporation catalog#40325) using ELISA kit (Enzyme-Linked Immunosorbent Assay). They were solved in DMSO (0.1%), and five serial

(2) Exploring market-approved azoles as potential breast cancer therapeutics targeting the VEGFR-2 biotargetSci RepDecember 10, 2025Asmaa M. Atta, Mohamed S. Nafie, Hashim A. Ali, Heba K. Saleh, Mohamed A. Roshdy, Mariam M. Mahmoud, Engy A. Eid, Marwa A. Ahmed, Mario S. Gerges, Ahmed M. Ghoneim, et al.values. They were tested for the VEGFR2 inhibition using VEGFR2 Kinase Inhibition Assay Kit Catalog # 40325 BPS Bioscience, San Diego, CA. Finally, the lead compound (ITR) was further tested using the SEC-bearing

(3) Discovery of Novel Piperidinyl-Based Benzoxazole Derivatives as Anticancer Agents Targeting VEGFR-2 and c-Met KinasesPharmaceuticals (Basel)December 9, 2025Wagdy M. Eldehna, Zainab M. Elsayed, Mohamed R. Elnagar, Ahmed H. El-Said, Taghreed A. Majrashi, Ahmed T. Negmeldin, Abdulrahman M. Saleh, Ranza Elrayess, Khaled A. Elnahriry, Zhi-Long Chen, et al.9.60%. 3.2. Biology Protocols 3.2.1. VEGFR-2 Inhibition Assay Using a VEGFR-2 Kinase Assay Kit (#40325; BPS Bioscience, San Diego, CA, USA), the drugs’ inhibitory efficacy against VEGFR-2 tyrosine kinase

(4) Activation of stimulator of interferon genes (STING) and inhibition of vascular endothelial growth factor receptor (VEGFR) by telatinib induce antitumor activityJournal of Biological ChemistryDecember 9, 2025Yi Wang, Yanfei Hou, Jing Han, Zhengyin Zhang, Yiyang Cheng, Jiaming Yang, Luqiu Mou, Shilong Fan, Peiyuan Liu, Kehong Chen, et al.and Brefeldin A (BFA) (#HY-16592) were purchased from MedChemExpress. VEGFR2 (KDR) Kinase Assay Kit (40325) was purchased from BPS Bioscience. Collagenase IV (C5138) was purchased from Sigma. DNase I (GMP-E127)

(5) Development of the 5-Nitrosalicaldehyde Arylhydrazones as Anticancer (MCF-7 and HCT116) Agents Targeting Inhibition of VEGFR-2 and Cytokines (IL-6 and TNF-α)ACS OmegaNovember 25, 2025Jackson K. Nkoana, Garland K. More, Ahmed A. Elhenawy, Malose J. Mphahleleinstructions employing the Human VEGFR-2 (KDR) kinase assay kit (BPS Bioscience Corporation catalog #40325). The test compounds 2a–l, as well as the reference standard, nintedanib, at concentrations 1, 5, 10,

(6) Rational Design and Synthesis of a Novel Series of Thiosemicarbazone-Containing Quinazoline Derivatives as Potential VEGFR2 InhibitorsPharmaceuticsFebruary 15, 2025Alexandru Șandor, Ovidiu Crișan, Gabriel Marc, Ionel Fizeșan, Ioana Ionuț, Cristina Moldovan, Anca Stana, Ilioara Oniga, Adrian Pîrnău, Laurian Vlase, et al.assessed using the Human VEGFR-2 (KDR) kinase assay kit (BPS Bioscience, San Diego, CA, USA, catalog #40325). The experimental assay was conducted according to the manufacturer’s instructions. An initial screening

(7) Novel NO-TZDs and trimethoxychalcone-based DHPMs: design, synthesis, and biological evaluation as potential VEGFR-2 inhibitorsJournal of enzyme inhibition and medicinal chemistryDecember 1, 2024Mahnashi MH, Nahari M, Almasoudi H, Alhasaniah A, Elgazwi S, Abou-Salim MA.BPS Bioscience® procedure17,83–86. Briefly, Kinase Buffer 1 (5×), ATP, and PTK substrate (50×) of KDR (Cat. No. 40325) were thawed, and 25 µl/well master mixture was prepared, added, and then the test compound CDHPM-10e

(8) Design, Synthesis, Pharmacological Evaluation of Quinazolin-4(3H)-Ones Bearing Urea Functionality as Potential VEGFR-2 InhibitorsDrug Design, Development and TherapyNovember 12, 2024Mohammad M Al-Sanea, Hani M Hafez, Ahmed A B Mohamed, Hamed W El-Shafey, Abdullah A Elgazar, Samar S Tawfik, Wafaa A Ewes, Shaimaa Hussein, Tariq G Alsahli, Abdelrahman Hamdiused to measure VEGFR-2 kinase activity. The VEGFR2 (KDR) Kinase assay kit (BPS Bioscience, Catalog # 40325) was added to 96-well plates with purified recombinant VEGFR-2 enzyme, VEGFR-2 substrate, ATP and kinase assay

(9) Enzyme (α-Glucosidase, α-Amylase, PTP1B & VEGFR-2) Inhibition and Cytotoxicity of Fluorinated Benzenesulfonic Ester Derivatives of the 5-Substituted 2-Hydroxy-3-nitroacetophenonesInternational Journal of Molecular SciencesNovember 5, 2024Temitope O. Olomola, Jackson K. Nkoana, Garland K. More, Samantha Gildenhuys, Malose J. Mphahlelecarried out employing the Human VEGFR-2 (KDR) kinase assay kit (BPS Bioscience Corporation catalogue #40325; San Diego, CA, USA). The procedure was carried out according to the manufacturer’s protocol by referring

(10) 1,2,4-Triazole-Tethered Indolinones as New Cancer-Fighting Small Molecules Targeting VEGFR-2: Synthesis, Biological Evaluations and Molecular DockingPharmaceuticals (Basel)January 8, 2024Ahmed E. Elsawi, Mai I. Shahin, Hager A. Elbendary, Tarfah Al-Warhi, Fatma E. Hassan, Wagdy M. Eldehna[35], whereas the VEGFR-2 inhibitory effect was assessed using VEGFR-2 Kinase Assay Kits (Cat. No. 40325 BPS Bioscience, San Diego, CA, USA) in accordance with the manufacturer’s instructions [21]. The examined

(11) Design and biological evaluation of 3-substituted quinazoline-2,4(1H,3H)-dione derivatives as dual c-Met/VEGFR-2-TK inhibitorsJournal of Enzyme Inhibition and Medicinal ChemistryDecember 31, 2023Abdelfattah Hassan, Fawzy A. F. Mubarak, Ihsan A. Shehadi, Ahmed M. Mosallam, Hussain Temairk, Mohamed Badr, Aboubakr H. Abdelmonsef2c, 2f, 4b, 4e, 4g, and 4h was performed by a well-known methodology of BPS KDR Assay Kit Catalog # 40325 (BPS Bioscience, San Diego, CA) (see Supplementary Data)8. Cell cycle analysis and apoptosis assay The

(12) Synthesis, biological evaluation and computer-aided discovery of new thiazolidine-2,4-dione derivatives as potential antitumor VEGFR-2 inhibitors†RSC AdvancesSeptember 18, 2023Hazem Elkady, Osama A. El-Dardir, Alaa Elwan, Mohammed S. Taghour, Hazem A. Mahdy, Mohammed A. Dahab, Eslam B. Elkaeed, Bshra A. Alsfouk, Ibrahim M. Ibrahim, Dalal Z. Husein, et al.against VEGFR-2 via the implementation of a VEGFR-2 ELISA kit (VEGFR2(KDR) Kinase Assay Kit Catalog # 40325) (BPS Bioscience, San Diego, USA).44 The ESI† file contains further information on this test. 2.2.3.

(13) Novel VEGFR2 inhibitors with thiazoloquinoxaline scaffold targeting hepatocellular carcinoma with lower cardiotoxic impactSci RepAugust 25, 2023Reham M. M. El-Hazek, Nashwa H. Zaher, Mostafa G. M. El-Gazzar, Noha A. Fadel, Walaa A. El-Sabbaghevaluation In vitro assay In-vitro VEGFR-2 kinase assay The VEGFR-2 Kinase Assay Kit [Catalog no., 40325, BPS Bioscience®, USA] is designed to measure VEGFR-2 kinase activity for screening and profiling applications

(14) New proapoptotic chemotherapeutic agents based on the quinolone-3-carboxamide scaffold acting by VEGFR-2 inhibitionScientific ReportsJuly 13, 2023Zeinab S. El-Fakharany, Yassin M. Nissan, Nada K. Sedky, Reem K. Arafa, Sahar M. Abou-Serikinase assay was performed using Kinase-Glo MAX Luminescence assay kit from BPS Bioscience (Catalog number: 40325). The results are presented as IC50 values (nM) ± SE and listed in Table 1. Most of the tested compounds

(15) Design, synthesis, and docking studies of novel pyrazole-based scaffolds and their evaluation as VEGFR2 inhibitors in the treatment of prostate cancer†RSC AdvancesJuly 7, 2023Dalia H. Soliman, Mohamed S. NafieVEGFR-2 kinase activity using a VEGFR2 (KDR) kinase assay kit (BPS Bioscience, Corporation catalog # 40325) according to the manufacturer's instructions. The percentage inhibition of autophosphorylation by substances

(16) A new class of anti-proliferative activity and apoptotic inducer with molecular docking studies for a novel of 1,3-dithiolo[4,5-b]quinoxaline derivatives hybrid with a sulfonamide moiety†RSC AdvancesApril 17, 2023Mostafa A. Ismail, Moustafa S. Abusaif, Mohamed S. A. El-Gaby, Yousry A. Ammar, Ahmed RagabCatalog #40321, EGFR(L858R) Kinase Assay Kit Catalog #40324, and VEGFR-2(KDR) Kinase Assay Kit Catalog #40325, respectively, according to the manufacturer's instructions. 4.3. Molecular docking simulations The

(17) Evaluation of the anti-proliferative activity of 2-oxo-pyridine and 1′H-spiro-pyridine derivatives as a new class of EGFRWt and VEGFR-2 inhibitors with apoptotic inducers†RSC AdvancesMarch 27, 2023Reham R. Raslan, Yousry A. Ammar, Sawsan A. Fouad, Sadia A. Hessein, Nadia A. M. Shmiess, Ahmed Ragabthe BPS-Bioscience EGFR Kinase Assay Kit Catalog # 40321 and VEGFR-2(KDR) Kinase Assay Kit Catalog # 40325, respectively according to the manufacturer's instructions. 4.4. Molecular docking simulations The

(18) Design, Synthesis, Docking Study, and Antiproliferative Evaluation of Novel Schiff Base–Benzimidazole Hybrids with VEGFR-2 Inhibitory ActivityMoleculesJanuary 4, 2023Hany M. Abd El-Lateef, Mohammed A. I. Elbastawesy, Tamer Mohamed Abdelghani Ibrahim, Mai M. Khalaf, Mohamed Gouda, Mariam G. F. Wahba, Islam Zaki, Martha M. Morcosswas performed by the established reported method using a VEGFR-2 (KDR) Kinase Assay Kit (Catalog # 40325, BPS Bioscience, Biotechnology company, San Diego, CA, USA) for selected synthetic compounds 3e and

(19) Facile Synthesis of Some Coumarin Derivatives and Their Cytotoxicity through VEGFR2 and Topoisomerase II InhibitionMoleculesNovember 28, 2022Mohamed S. Gomaa, Ibrahim A. I. Ali, Gaber El Enany, El Sayed H. El Ashry, Samir M. El Rayes, Walid Fathalla, Abdulghany H. A. Ahmed, Samar A. Abubshait, Haya A. Abubshait, Mohamed S. Nafie[49,50,51]. 3.3.2. Enzyme Target Assays VEGFR2 (KDR) kinase assay kit “BPS Bioscience Corporation catalog#40325” and Topo isomearse II screening kit “TopoGEN, Inc., Columbus, OH, USA” were utilized to invetstiage

(20) Chlorinated benzothiadiazines inhibit angiogenesis through suppression of VEGFR2 phosphorylationBioorganic & Medicinal ChemistryAugust 1, 2022Bader I. Huwaimel, Sravan Jonnalagadda, Shirisha Jonnalagadda, Fatema T. Zahra, Alessio Nocentini, Claudiu T. Supuran, Constantinos M. Mikelis, Paul C. Trippier43 VEGFR2 Inhibition Assay. Was carried out using BPS Bioscience VEGFR2 kinase assay kit (Catalog # 40325) according to the manufacturer’s protocol. Briefly, test compounds were dissolved in DMSO and further

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VEGFR2 (KDR) Kinase Assay Kit

VEGFR2 (KDR) Kinase Assay Kit

VEGFR2 (KDR) Kinase Assay Kit from BPS Bioscience, Inc.

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BPS Bioscience, Inc.

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VEGFR2 (KDR) Kinase Assay Kit from BPS Bioscience, Inc.

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