Fig 1: Effects of Nrf2 intervention on the ARE in the modeled mice with COPD-related sarcopenia. A–D The concentrations of HO-1 (A), GST (B), T-SOD (C) and MDA (D) tested in the mice of each group. Data of independent triplicates were presented as mean ± SD and the statistical significance between two groups was marked with different asterisks (* means p < 0.05, and ** means p < 0.01). All p-values were calculated by comparing each experimental group (COPD, COPD + SFN, COPD + ML385) with the control group (CON). Nrf2 nuclear factor erythroid-2-related factor 2, CON Control, COPD chronic obstructive pulmonary disease, SFN sulforaphane (Nrf2 agonist), HO-1 heme oxygenase 1, GST glutathione-S-transferase, T-SOD total superoxide dismutase, MDA malondialdehyde