Description
Product Characteristics: This immunoassay kit allows for the in vitro quantitative determination of human zinc finger e-box-binding homeobox 2, ZEB2 concentrations in serum, plasma, tissue homogenates, cell culture supernates, and other biological fluids.
Target Information: The protein encoded by this gene is a member of the Zfh1 family of 2-handed zinc finger/homeodomain proteins. It is located in the nucleus and functions as a DNA-binding transcriptional repressor that interacts with activated SMADs. Mutations in this gene are associated with Hirschsprung disease/Mowat-Wilson syndrome. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jan 2010]