COX-2 (human) Inhibitor Screening Assay Kit 701080 from Cayman Chemical

Product Specs
ItemCOX-2 (human) Inhibitor Screening Assay Kit
CompanyCayman Chemical
Price $549.00Supplier Page View Company Product Page
Catalog Number701080
Quantity96 Well
Reactivityhuman
ApplicationsScreening
Source/Expression SystemAnimal/Sheep
Research AreaCyclooxygenase Pathway, Immunology & Inflammation, Inflammatory Lipid Mediators, Lipid Biochemistry, Prostaglandins
Storage-80
OriginUSA

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Cayman Chemical

Cayman Chemical Company 1180 East Ellsworth Road

Ann Arbor, Michigan 48108

United States

Phone: (800) 364-9897
(734) 971-3640

Company Profile

Website: http://www.caymanchem.com/

(1) Multi-analytical and biological insights into Malcolmia grandiflora KuntzeSci RepApril 21, 2026Ahlam Hashem Elwekeel, Enas I. A. Mohamed, Elham Amin, Malak Sadek, Mahytab Mohamed, Marwa H. A. Hassanscreening, and the procedures followed the manufacturer’s instructions (catalog numbers 701070 and 701080 from Cayman Chemical)90,91. The full method is provided in the supplementary material. Cytotoxic activity The

(2) Evaluation of antiviral activity indicators in selected medicinal plants used traditionally for treatment of respiratory viral infectionsBMC Complementary Medicine and TherapiesMarch 9, 2026Sithembiso Lethukuthula Ndwandwe, Vuyisile Samuel Thibane, Sechene Stanley Gololo(COX-2) inhibition was determined using colorimetric COX-2 inhibitor screening assay kit (Item No. 701080, Cayman Chemical). The COX reaction Procedure The Cox-2 enzyme was prepared by mixing 80 µl of enzyme

(3) GC–MS characterization and in-silico evaluation of TNF-α binding efficacy of leaf extract from Abies spectabilis (D. Don) SpachScientific ReportsJanuary 9, 2026Chirag Prajapati, Lovelesh Singh Saini, Arti Gaur, Pankaj Kumar, Jalal Uddin, Rozidaini Mohd Ghazileaf extract using commercially available enzyme immunoassay (EIA) kits from Cayman Chemical (Cat. No. 701080, 701,070)15,16. All procedures followed the manufacturer’s instructions with minor adjustments for extract

(4) Antioxidant and Anti-Inflammatory Activities from Optimum Formula of Spatholobus littoralis Hassk. and Sauropus androgynus L.: In Vitro and In Silico StudiesCurrent Issues in Molecular BiologyNovember 21, 2025Rut Novalia Rahmawati Sianipar, Dyah Iswantini, Charlena Charlena, Setyanto Tri Wahyudi, Joni Prasetyo, Trivadila Trivadilaactivity was assessed using the COX-2 (Human) Inhibitor Screening Assay kit (Cayman Chemical, Item no. 701080). The optimal extract and formulation were selected for the COX-2 inhibition test. The procedure followed

(5) Lipidomics‐Guided Ultrasound‐Assisted Ethanol Extraction of Avocado Pulp and Evaluation of Bioactive PropertiesJournal of Food ScienceOctober 1, 2025Bruna B. Neves, Rita Pais, Joana Batista, Marisa Pinho, Tatiana Maurício, Stefano Bonciarelli, Laura Goracci, Bruno Neves, Pedro Domingues, M. Rosário Domingues, et al.cyclooxygenase‐2 (COX‐2) inhibitory screening assay kit following the manufacturer's instructions (Cayman test kit‐701080, Cayman Chemical Company, Ann Arbor, MI, USA). Three different concentrations (final concentration of

(6) From By-Product to Bioactive Molecular Ingredient: The Impact of Cranberry Pomace on Antioxidant Properties and Enzyme Modulation in Functional BiscuitsInternational Journal of Molecular SciencesSeptember 16, 2025Natalia Matłok, Tomasz Piechowiak, Ireneusz Kapusta, Maciej BalawejderCOX-2 activity was determined using commercial assay kits from Cayman Chemical (cat. no. 701070 and 701080). AChE inhibition was measured using a Sigma-Aldrich (Saint Louis, MO, USA) assay (cat. no. MAK324).

(7) Palmitoyl-Epigallocatechin Gallate Modulates COX-2-Based Production of Inflammation-Related Oxylipins: Synthesis, Characterization, and Bioevaluation In Vitro and In SilicoACS OmegaAugust 12, 2025Concepción Medrano-Padial, Pablo Fuentes-Soriano, Diego Hernández-Prieto, Cristina García-Viguera, Raúl Domínguez-Perles, Carlos Romero-Nieto, Sonia Medinawith a specific ELISA kit according to the manufacturer’s instructions (Cayman Chemicals, Item No. 701080, Michigan, USA). Briefly, this assay directly measured PFG2α by stannous chloride (SnCl2) reduction

(8) Integrative Wound-Healing Effects of Clinacanthus nutans Extract and Schaftoside Through Anti-Inflammatory, Endothelial-Protective, and Antiviral MechanismsInternational Journal of Molecular SciencesJune 23, 2025Nipitpawn Limpanich, Pattarasuda Chayapakdee, Kullanun Mekawan, Saruda Thongyim, Rujipas Yongsawas, Phanuwit Khamwong, Yingmanee Tragoolpua, Thida Kaewkod, Siriphorn Jangsutthivorawat, Jarunee Jungklang, et al.compounds against COX-2 was assessed using a commercial COX (human) inhibitor screening kit (Cat. No. 701080, Cayman Chemical, Ann Arbor, MI, USA), following the manufacturer’s instructions. Briefly, 10 μL of

(9) Inhibition of Inflammatory Regulators for Chronic Obstructive Pulmonary Disease (COPD) Treatment from Indonesian Medicinal Plants: A Systematic ReviewCurr Issues Mol BiolApril 8, 2025Dyah Iswantini, Min Rahminiwati, Trivadila Trivadila, Siti Sadiah, Novriyandi Hanif, Rut Novalia Rahmawati Sianipar, Susi IndarianiELISA method using the COX Inhibitor Screening Assay Kit and following the Cayman Chemical Catalog No. 701080 protocol. At a dose of 1000 μg/mL, the 96% ethanol extract of legetan warak inhibited 98.47% of the

(10) Validating anti-inflammatory and cytotoxic properties of Fagonia cretica L. through metabolic, in vitro, and in silico profilingBMC Complementary Medicine and TherapiesNovember 28, 2024Enas I. A. Mohamed, Ahlam H. Elwekeel, Dalia El Amir Mohamed, Mohamed A. Zaki, Marwa H. A. Hassanand COX-1 inhibitor screening kit according to the manufactures protocol (catalog number 701070 and 701080, respectively, Cayman Chemical, Ann Arbor, MI, USA) [18, 19]. The samples to be tested were dissolved

(11) Bioactive Lipids in Dunaliella salina: Implications for Functional Foods and HealthFoodsOctober 19, 2024Rita Pais, Tiago Conde, Bruna B. Neves, Marisa Pinho, Marta Coelho, Hugo Pereira, Alexandre M. C. Rodrigues, Pedro Domingues, Ana Maria Gomes, Ralph Urbatzka, et al.determined using the commercial cyclooxygenase-2 (COX-2) inhibitory screening assay kit (Cayman test kit-701080 (Cayman Chemical Company, Ann Arbor, MI, USA)), according to the manufacturer’s instructions. The dried

(12) Anti-Inflammatory Effects of Hydroethanolic Extract from Ehretia asperula on Lipopolysaccharide-Stimulated RAW264.7 MacrophagesJournal of Microbiology and BiotechnologyJune 28, 2024Bao Le, Vo Thi Kim Hong, Seung Hwan YangChemical (USA). A COX-2 (human) Inhibitor Screening Assay Kit was purchased from Cayman Chemical (#701080, Ann Arbor, USA). An EZ-Cytox Cell Viability Assay Kit was purchased from Daeil Lab Service (Republic

(13) Pharmacological and behavioral investigation of putative self-medicative plants in Budongo chimpanzee dietsPLOS ONEJune 20, 2024Elodie Freymann, Susana Carvalho, Leif A. Garbe, Dinda Dwi Ghazhelia, Catherine Hobaiter, Michael A. Huffman, Geresomu Muhumuza, Lena Schulz, Daniel Sempebwa, Florian Wald, et al.assay Anti-inflammatory assays were assessed using an in vitro COX inhibitor screening assay kit (Cayman Item No: 701080), with modifications previously described in Schultz et al. [74]. All extracts were first screened in

(14) Polar Lipids of Marine Microalgae Nannochloropsis oceanica and Chlorococcum amblystomatis Mitigate the LPS-Induced Pro-Inflammatory Response in MacrophagesMar DrugsDecember 6, 2023Tiago Conde, Bruno Neves, Daniela Couto, Tânia Melo, Diana Lopes, Rita Pais, Joana Batista, Helena Cardoso, Joana Laranjeira Silva, Pedro Domingues, et al.This assay was performed using the commercial COX-2 inhibitory screening assay kit—Cayman test kit-701080 (Cayman Chemical Company, Ann Arbor, MI, USA)—and was carried out according to the manufacturer’s instructions.

(15) In Vitro Analysis of Selected Antioxidant and Biological Properties of the Extract from Large-Fruited Cranberry FruitsMoleculesDecember 1, 2023Maciej Balawejder, Tomasz Piechowiak, Ireneusz Kapusta, Aleksandra Chęciek, Natalia MatłokCOX-2 by cranberry extracts was assessed using commercial kits from Cayman (catalog numbers: 701070, 701080). The assays involved incubating COX-1 or COX-2 with cranberry extract over a concentration range of

(16) Synthesis and Biological Evaluation of Some New 3-Aryl-2-thioxo-2,3-dihydroquinazolin-4(1H)-ones and 3-Aryl-2-(benzylthio)quinazolin-4(3H)-ones as Antioxidants; COX-2, LDHA, α-Glucosidase and α-Amylase Inhibitors; and Anti-Colon Carcinoma and Apoptosis-Inducing AgentsPharmaceuticals (Basel)October 1, 2023Nahed Nasser Eid El-Sayed, Taghreed M. Al-Otaibi, Assem Barakat, Zainab M. Almarhoon, Mohd. Zaheen Hassan, Maha I. Al-Zaben, Najeh Krayem, Vijay H. Masand, Abir Ben Bacha(50, 100, 200 and 300 µg/mL) using a commercial COX-2 inhibitory screening assay kit (Catalog Number: 701080; Cayman Chemical Company) following the manufacturer’s instructions. Briefly, 10 µL of the tested compound

(17) Microbial Transformation of the Sesquiterpene Lactone, Vulgarin, by Aspergillus nigerMoleculesApril 26, 2023Reem A. ElGamal, Amal A. Galala, Maged S. Abdel-Kader, Farid A. Badria, Amal F. Solimanhuman enzyme inhibitory assay kit (No. 701070), COX-2 Cayman human enzyme inhibitory assay kit (No. 701080, USA), and ROBONIK P2000 EIA reader. Evaluation of the data was performed by using Four Parameter Logistic

(18) Versatile Platinum(IV) Prodrugs of Naproxen and Acemetacin as Chemo-Anti-Inflammatory AgentsCancers (Basel)April 26, 2023Angelico D. Aputen, Maria George Elias, Jayne Gilbert, Jennette A. Sakoff, Christopher P. Gordon, Kieran F. Scott, Janice R. Aldrich-WrightCOX-2 inhibitory characteristics of 1–6, the COX-2 (human) Inhibitor Screening Assay Kit (Item No. 701080, Cayman Chemical, Ann Arbor, MI, USA) was used (see Supplementary Materials). 3. Results and Discussion 3.1.

(19) Differences and Similarities in Lipid Composition, Nutritional Value, and Bioactive Potential of Four Edible Chlorella vulgaris StrainsFoodsApril 12, 2023Tatiana Maurício, Daniela Couto, Diana Lopes, Tiago Conde, Rita Pais, Joana Batista, Tânia Melo, Marisa Pinho, Ana S. P. Moreira, Mafalda Trovão, et al.assay was carried out using the commercial COX-2 inhibitory screening assay kit, a Cayman test kit-701080 (Cayman Chemical Company, Ann Arbor, MI, USA), and was performed according to the manufacturer instructions.

(20) Evaluation of Lipid Extracts from the Marine Fungi Emericellopsis cladophorae and Zalerion maritima as a Source of Anti-Inflammatory, Antioxidant and Antibacterial CompoundsMarine DrugsMarch 23, 2023Mariana Abraúl, Artur Alves, Sandra Hilário, Tânia Melo, Tiago Conde, Maria Rosário Domingues, Felisa Reycyclooxygenase (COX-2) inhibitory screening assay was performed using a commercial kit, Cayman test kit-701080, from Cayman Chemical Company (Ann Arbor, MI, USA). All the other reagents and chemicals used were of

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COX-2 (human) Inhibitor Screening Assay Kit

COX-2 (human) Inhibitor Screening Assay Kit

COX-2 (human) Inhibitor Screening Assay Kit from Cayman Chemical

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Cayman Chemical

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COX-2 (human) Inhibitor Screening Assay Kit from Cayman Chemical

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