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COX Colorimetric Inhibitor Screening Assay Kit
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COX Colorimetric Inhibitor Screening Assay Kit
COX Colorimetric Inhibitor Screening Assay Kit
COX Colorimetric Inhibitor Screening Assay Kit from Cayman Chemical
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Citations:
(52)
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COX Colorimetric Inhibitor Screening Assay Kit
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Description
A colorimetric assay for the screening of isozyme-specific inhibitors
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
COX Colorimetric Inhibitor Screening Assay Kit
Company
Cayman Chemical
Price
$908.00
Supplier Page
View Company Product Page
Catalog Number
701050
Storage
-80
Origin
USA
Applications
Screening
Source/Expression System
Animal/Sheep
Research Area
Cyclooxygenase Pathway, Immunology & Inflammation, Inflammatory Lipid Mediators, Lipid Biochemistry, Prostaglandins
Quantity
192 Well
Add to Compare List
Cayman Chemical
Cayman Chemical Company 1180 East Ellsworth Road
Ann Arbor
,
Michigan
48108
United States
Phone
: (800) 364-9897
(734) 971-3640
Company Profile
Website:
http://www.caymanchem.com/
Citations (52)
(1)
The Activation of Aldehyde Dehydrogenase 2 (ALDH2) by Alda-1 and Flurbiprofen as a Common Mechanism to Reduce Alcohol Intake in Rats
Int J Mol Sci
April 3, 2026
Juan Manuel Torres, Carolina Ponce, Vicente Pérez, Ignacio Gutiérrez-Vega, María Elena Quintanilla, David Vásquez, Mario Rivera-Meza
on COX-1 and COX-2 Activity A COX-1/2 Colorimetric
Inhibitor Screening
Assay
Kit (
Cayman
Item No.
701050
) was used to evaluate the inhibitory activity of
Alda-1
and flurbiprofen. For the evaluation of COX-1
(2)
Navigating the conjugated metabolome
bioRxiv
February 12, 2026
Shipei Xing, Abubaker Patan, Julius Agongo, Harsha Gouda, Vincent Charron-Lamoureux, Yasin El Abiead, Zhewen Hu, Haoqi Nina Zhao, Ipsita Mohanty, Jasmine Zemlin,
et al.
inhibition was assessed using the
COX Colorimetric Inhibitor Screening Assay Kit
(
Cayman Chemical
, Item No.
701050
) according to the manufacturer’s instructions. Test compounds, including ibuprofen, ibuprofen-ethanolamine,
(3)
Exploring Ochradenus baccatus: A Novel Source of Bioactive Compounds and Phytochemical Insights for Uncharted Therapeutic Applications
Life (Basel)
September 16, 2025
Salma Saddeek
Biological Assays
2.4.1. Anti-Inflammatory Activity COX-1/COX-2 inhibition assessed via
ELISA
(
Cayman Chemical
Kit #
701050
, Ann Arbor, MI, USA) [30].Extract concentration: 100 µg/mL. Selectivity Index = (COX-2 %Inh)/(COX-1
(4)
Implications of Pleurotus ostreatus solid-state bioprocessing on the nutritional composition, protein structure, and anti-hypertensive and anti-inflammatory potential of local beans (Phaseolus vulgaris L.)
Curr Res Food Sci
August 12, 2025
Sara Muñoz-Pina, Kateryna Khvostenko, Jorge García-Hernández, Ana Heredia, Ana Andrés
obtained from Panreac AppliChem (Barcelona, Spain).
COX Colorimetric Inhibitor Screening Assay Kit
(
701050
-192) was obtained from
Cayman Chemical
(Ann Arbor, MI). 2.2 Fungal solid-state fermentation (SSF) of
(5)
Oxalis erythrorhiza Gillies ex Hooker et Arnott (Oxalidaceae): Chemical Analysis, Biological In Vitro and In Vivo Properties and Behavioral Effects
Antioxidants (Basel)
December 7, 2024
Jessica Gómez, Mario J. Simirgiotis, María Sol Kruse, Carlos Gamarra-Luques, Beatriz Lima, José Zaragosa, Mauricio Piñeiro, Alejandro Tapia, Héctor Coirini, Mariana Rey
and 72 µg/mL) on
COX-1 (ovine
) and COX-2 (
human
) was determined using a commercial colorimetric kit
701050
(
COX Colorimetric Inhibitor Screening Assay Kit
,
Cayman Chemical
Co., Ann Arbor, MI, USA) following
(6)
Skin anti-aging potential of Launaea procumbens extract: Antioxidant and enzyme inhibition activities supported by ADMET and molecular docking studies
Saudi Pharmaceutical Journal
July 1, 2024
Hanan Khojah, Shaima R. Ahmed, Shahad Y. Alharbi, Kholood K. AlSabeelah, Hatham Y. Alrayyes, Kadi B. Almusayyab, Shahad R. Alrawiliy, Raghad M. Alshammari, Sumera Qasim
obtained from Sigma Chemical Co. (St. Louis, MO, USA).
COX Colorimetric Inhibitor Screening Assay Kit
(No.
701050
,
Cayman Chemical
, Ann Arbor, Michigan, USA). Positive controls, including butylated hydroxytoluene (BHT),
(7)
Generation, Characterisation and Identification of Bioactive Peptides from Mesopelagic Fish Protein Hydrolysates Using In Silico and In Vitro Approaches
Marine Drugs
June 27, 2024
Maria Hayes, Azza Naik, Leticia Mora, Bruno Iñarra, Jone Ibarruri, Carlos Bald, Thibault Cariou, David Reid, Michael Gallagher, Ragnhild Dragøy,
et al.
96 well plate format using the
assay
kit—COX colourimetric inhibition
screening
assay
kit (Item No.
701050
) from
Cayman Chemicals
(Cayman chemicals, Ellsworth Rd., Ann Arbor, MI, USA). Resveratrol (Sigma, Dublin,
(8)
Synthesis, docking and biological evaluation of purine-5-N-isosteresas anti-inflammatory agents†
RSC Advances
May 28, 2024
Ahmed M. El-Saghier, Souhaila S. Enaili, Aly Abdou, Amany M. Hamed, Asmaa M. Kadry
11 and 12 might
inhibit
COX enzymes. A
COX colorimetric inhibitor screening assay kit
(Catalog No.
701050
,
Cayman Chemical
Inc., Ann Arbor, MI, USA) was used to assess the inhibitory activity for COX-1 and
(9)
Comparative Assessment of Lignan Profiling and Biological Activities of Schisandra henryi Leaf and In Vitro PlantForm Bioreactor-Grown Culture Extracts
Pharmaceuticals (Basel)
March 29, 2024
Karolina Jafernik, Paweł Kubica, Michał Dziurka, Łukasz Kulinowski, Izabela Korona-Głowniak, Hosam O. Elansary, Piotr Waligórski, Krystyna Skalicka-Woźniak, Agnieszka Szopa
of
COX-1
and COX-2, samples were tested using a
COX-1 (ovine
) and COX-2 (
human
)
inhibitor
assay
kit (
701050
,
Cayman
Chem. Co., MI, USA) as per the manufacturer’s instructions, with arachidonic acid at 1.1 mM
(10)
Anti-inflammatory activity of verbascoside- and isoverbascoside-rich Lamiales medicinal plants
Heliyon
January 15, 2024
Benyakan Pongkitwitoon, Waraporn Putalun, Kanokporn Triwitayakorn, Tharita Kitisripanya, Tripetch Kanchanapoom, Panitch Boonsnongcheep
inhibitory activities of the samples were assessed using a
COX colorimetric inhibitor screening assay kit
(
701050
,
Cayman Chemical
, USA). The
assay
was performed following the manufacturer's recommended protocol. The
(11)
Malvidin and Its Mono- and Di-Glucosides Forms: A Study of Combining Both In Vitro and Molecular Docking Studies Focused on Cholinesterase, Butyrylcholinesterase, COX-1 and COX-2 Activities
Molecules
November 30, 2023
Paulina Strugała-Danak, Maciej Spiegel, Janina Gabrielska
Merck kGaA
, Darmstadt, Germany. COX-1 and COX-2 colorimetric
inhibitor screening
assay
kits (Catalog No.
701050
) were purchased from
Cayman Chemical
, Ann Arbor, MI, USA. Malvidin (purity ≥ 97%), malvidin 3-O-glucoside
(12)
Influence of Soluble Fiber as a Carrier on Antioxidant and Physical Properties of Powders Produced Based on the Spray Drying of Malvae arboreae flos Aqueous Extracts
Foods
September 7, 2023
Katarzyna Lisiecka, Dariusz Dziki, Urszula Gawlik-Dziki, Michał Świeca, Renata Różyło
(cyclooxygenase-2) activities was tested using a
COX Colorimetric Inhibitor Screening Assay Kit
(
Cayman
, No.
701050
). All measurements were performed in triplicate. One unit of
inhibitor
activity (IU) was defined as
(13)
Olive Mill Wastewater as Source of Polyphenols with Nutraceutical Properties
Nutrients
August 26, 2023
Doretta Cuffaro, Andrea Bertolini, Simone Bertini, Claudio Ricci, Maria Grazia Cascone, Serena Danti, Alessandro Saba, Marco Macchia, Maria Digiacomo
and COX-2 was evaluated using a
COX-1 (ovine
) and
COX-2 (human)-inhibitor screening assay (kit
No.
701050
from
Cayman Chemical
Co., Ann Arbor, MI, USA) following the manufacturer’s protocols. COX-1/COX-2 inhibitory
(14)
Synthesis, Biological, Spectroscopic and Computational Investigations of Novel N-Acylhydrazone Derivatives of Pyrrolo[3,4-d]pyridazinone as Dual COX/LOX Inhibitors
Molecules
July 18, 2023
Jakub Mikus, Piotr Świątek, Patrycja Przybyła, Edward Krzyżak, Aleksandra Marciniak, Aleksadra Kotynia, Aleksandra Redzicka, Benita Wiatrak, Paulina Jawień, Tomasz Gębarowski,
et al.
incubation
at 100 µM concentration using the
Cayman
’s
COX Colorimetric Inhibitor Screening Assay Kit
(Cat #
701050
). Three worldwide known NSAIDs—meloxicam, celecoxib, and diclofenac—have been used as references. The
(15)
m-Terphenylamines, Acting as Selective COX-1 Inhibitors, Block Microglia Inflammatory Response and Exert Neuroprotective Activity
Molecules
July 13, 2023
Damiano Rocchi, Juan F. González, Olmo Martín-Cámara, Maria Grazia Perrone, Morena Miciaccia, Antonio Scilimati, Celine Decouty-Pérez, Esther Parada, Javier Egea, J. Carlos Menéndez
of the enzyme was evaluated by using a colorimetric
COX inhibitor screening assay kit
(Catalog No.
701050
,
Cayman Chemicals
, Ann Arbor, MI, USA) following the manufacturer’s instructions. The
assay
kit
measures
(16)
Stability Analysis of the Asiatic Acid-COX-2 Complex Using 100 ns Molecular Dynamic Simulations and Its Selectivity against COX-2 as a Potential Anti-Inflammatory Candidate
Molecules
April 27, 2023
Ida Musfiroh, Rahmana E. Kartasasmita, Slamet Ibrahim, Muchtaridi Muchtaridi, Syahrul Hidayat, Nur Kusaira Khairul Ikram
Chemical, Ann Arbor, MI, USA), tris-HCl buffer, and a Colorimeter
COX Inhibitor Screening Assay Kit
701050
(
Cayman Chemical
, Ann Arbor, MI, USA). The pieces of software used in this research are the AMBER18
(17)
In Vitro Pharmacological Activity, and Comparison GC-ToF-MS Profiling of Extracts from Cissus cornifolia (Baker) Planch
Life (Basel)
March 8, 2023
Nkoana I. Mongalo, Maropeng Vellry Raletsena, Rabelani Munyai
resulting from COX oxidation of arachidonic acid, using a
screening
assay
kit (
Cayman Chemical
, Item No.
701050
) [27]. Shortly, 10 µL of the
inhibitors
at different concentrations were added to the different wells,
(18)
Enhanced Nutraceutical Properties of Extra Virgin Olive Oil Extract by Olive Leaf Enrichment
Nutrients
February 21, 2023
Doretta Cuffaro, Simone Bertini, Marco Macchia, Maria Digiacomo
and COX-2 was evaluated using a
COX-1 (ovine
) and
COX-2 (human)-inhibitor screening assay (kit
No.
701050
from
Cayman Chemical
Co. Michigan, USA), following the manufacturer’s protocols. An initial COX-1/COX-2
(19)
Transient inhibition of microsomal prostaglandin E synthase-1 after status epilepticus blunts brain inflammation and is neuroprotective
Molecular brain
January 25, 2023
Yasmen N, Sluter MN, Li L, Yu Y, Jiang J.
groups. COX inhibition
assay
The
COX Colorimetric Inhibitor Screening Assay Kit
(
Cayman Chemical
, Cat. #
701050
) was used to evaluate the inhibition percentage of COX enzyme by tested compounds following the manufacturer’s
(20)
Analysis of Phenolic Compounds in Buckwheat (Fagopyrum esculentum Moench) Sprouts Modified with Probiotic Yeast
Molecules
November 11, 2022
Marta Molska, Julita Reguła, Ireneusz Kapusta, Michał Świeca
in vitro
, was determined using a
COX colorimetric inhibitor screening assay kit
(
Cayman Chemical
, No.
701050
). The results were expressed in inhibitory units (UIs) per g d.w. One IU was defined as inhibition of
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Reviews
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COX Colorimetric Inhibitor Screening Assay Kit from Cayman Chemical
Supplier Page
View Company Product Page
$908.00
Product Specs
Company Info
Citations
Reviews
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