Lipid Peroxidation (4-HNE) Assay Kit ab238538 from Abcam

Product Specs
ItemLipid Peroxidation (4-HNE) Assay Kit
CompanyAbcam
Price Supplier Page View Company Product Page
Catalog Numberab238538
Quantity32 Test, 96 Test
Sample TypeSerum, Plasma, Cell Lysate, Purified protein, Tissue Lysate
Research AreaImmuno-oncology

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Website: http://www.abcam.com

(1) SGLT2 Inhibitor Dapagliflozin Attenuates Cardiomyocyte Injury and Inflammation Induced by PI3Kα-Selective Inhibitor Alpelisib and Fulvestrant Under HyperglycemiaInt J Mol SciApril 17, 2026Vincenzo Quagliariello, Massimiliano Berretta, Matteo Barbato, Fabrizio Maurea, Maria Laura Canale, Andrea Paccone, Irma Bisceglia, Andrea Tedeschi, Marino Scherillo, Jacopo Santagata, et al.measured using a human-specific ELISA-based lipid peroxidation assay (Lipid Peroxidation 4-HNE Assay Kit, ab238538; Abcam, Milan, Italy). Standards and samples were added to pre-coated 96-well plates and incubated according

(2) The HIF-2 transcription factor mediates resistance to ferroptosis in pancreatic cancerMol CellApril 2, 2026Maimon E. Hubbi, Catherine L. Wang, Yasir Suhail, Nadia L. Almasri, Jane Xie, Erin E. Hollander, Kshitiz, Alexander Muir, Ben Z. Stanger, Chi V. Dangcommercial assays Cell-Titer Glo,Promega,Cat# 7570 Lipid Peroxidation (4-HNE) Assay Kit,Abcam,Cat# ab238538 Dual Luciferase Assay Kit,Promega,Cat# E1910 Chromatin IP Kit,Cell Signaling Tech,Cat# 9003 RNeasy

(3) Ferroptosis‐Driven Neuronal Damage Exacerbation in Diabetic Stroke: Implications of SLC7A11 InhibitionCNS Neuroscience & TherapeuticsMarch 12, 2026Siyuan Liu, Min Liu, Binbin Wang, Miao Sun, Huikai Yang, Mengyao Qu, Libin Ma, Likai Shi, Yuxiang Song, Peng Li, et al.and 4‐HNE were measured using the MDA Assay Kit (Nanjing Jiancheng, China) and the 4‐HNE Assay Kit (ab238538, Abcam, UK), in accordance with the manufacturer's protocols. Results for MDA and 4‐HNE were expressed

(4) Visnagin Protects Against Lipopolysaccharide-Induced Acute Kidney Injury by Inhibiting Oxidative Stress and Reducing FerroptosisInt J Med SciFebruary 18, 2026Sheng-Wen Wu, Chen-Yu Chiang, Chien-Ying Lee, Shiuan-Shinn Lee, Wen-Ying Chen, Chun-Jung Chen, Ching-Chi Tseng, Yin-Che Lu, Yu-Hsiang Kuan(4-HNE) by using the TBARS assay kit (Cat: 10009055, Cayman, MI, USA) and 4-HNE ELISA assay kit (Cat: ab238538, Abcam, MA, USA), respectively. Fe²⁺ concentrations were determined using an iron assay kit (Cat: ab83366,

(5) CREB5 Inhibits Neuronal Ferroptosis via Transactivating ApoL6 to Regulate Lipid Droplet Metabolism After Spinal Cord InjuryCNS Neuroscience & TherapeuticsFebruary 17, 2026Xiaolong Xi, Zhensen Chen, Chaojun Wang, Fei Wang, Xuedong Sunacquisition of precise quantitative data on ROS. Additionally, a specialized detection kit (ab118970, ab238538, Abcam) was used to measure the levels of lipid peroxidation products in lysates of primary neurons,

(6) Mitochondrial energetic failure underlies FLVCR1-related sensory neuropathyCommunications BiologyFebruary 14, 2026Francesca Bertino, Diletta Isabella Zanin Venturini, Eleonora Grasso, Joanna Kopecka, Chiara Salio, Barbara Gnutti, Ram Manohar Basnet, Stefania Bellini, Luca Mignani, Boxun Zhao, et al.cytosolic extracts, obtained as reported above, by using the Lipid Peroxidation (4-HNE) Assay Kit (Abcam; ab238538) that evaluates the 4-hydroxy-nonenal, one of the thiobarbituric reactive substances used as an indicator

(7) Modified Sanjia Powder ameliorates cognitive impairment and exerts neuroprotective effects in 5 × FAD mice: insights from quantitative proteomicsFrontiers in NutritionJanuary 16, 2026Yifan Wang, Chenxi Liu, Xiaoyan Zheng, Zhiqiang Wang, Yufan Wang, Yi Geng, Jin Yang, Kaifeng Wei, Xiaoying ChenPeroxidation (MDA) Assay Kit (Sigma-Aldrich, MAK085) and Lipid Peroxidation (4-HNE) Assay Kit (Abcam, ab238538), following the manufacturer's instructions. 2.11 Statistical analysis Statistical analyses were performed

(8) Osteoarthritis pathogenesis Unveiled: DMT1 drives autophagy-dependent ferroptosis through a mir-17-5p/NEDD4 regulatory axisJournal of Orthopaedic TranslationJanuary 8, 2026Guanglei Zhao, Yue Shen, Jingchun Ma, Xin Huang, Jie Chen, Jingsheng Shi, Jun xia, Siqun Wang, Gangyong Huang, Weigang Wu4-HNE The MDA Assay kit (E-BC-K025-M, Elabscience), GSH Assay Kit (KTB1600, Abbkine) and 4-HNE Assay Kit (ab238538, Abcam), were employed for determination in accordance with the manufacturer's guidelines. The intracellular

(9) Methotrexate-triggered ferroptosis suppresses oral cancer progression by phosphorylated KEAP1-mediated NRF2 degradation to inhibit SLC7A11/GPX4 signaling pathwayCancer Cell InternationalJanuary 6, 2026Chenchen Yu, Tingting Zhang, Jialu Yuan, Yijing Su, Hongli Zhang, Liqin Xu, Xiaomin Li, Jianan Cui, Rui Xu, Yan Zhou, et al.Cystine uptake fluorometric assay kit (E-BC-F066) were purchased from Elabscience (Wuhan, China). Lipid peroxidation (4-HNE) assay (ab238538) and Glutamate assay (ab83389) were purchased from Abcam (Shanghai, China). The primary antibodies,

(10) From kidney injury to cardiac dysfunction: the central role of oxidative stress in diabetes and CKDBasic Research in CardiologyDecember 19, 2025Payel Sen, Theresa Sittig, Jules Hamers, Laura d’Ambrosio, Irem Ornek, Junqing Zhang, Bachuki Shashikadze, Jan B. Stöckl, Marie Bachter, Susanne Bierschenk, et al.GmbH, Jena, Germany). Subsequently, 4-HNE protein adducts were measured using a colorimetric assay (ab238538 Abcam, Berlin, Germany), according to the manufacturer’s instructions. Glutathione peroxidase (GPX)

(11) Neuroprotective Effects of N-Acetylcysteine-Amide (AD4) in a Survival Mouse Model of Paraoxon Intoxication: Targeting Oxidative Stress, Neuroinflammation and Memory ImpairmentsAntioxidants (Basel)December 6, 2025Edurne Urquizu, Marine Cuiller, Georgia Papadopoulou, David Pubill, Demetrio Raldúa, Jordi Camarasa, Elena Escubedo, Raul López-Arnau4-HNE concentration assay. Quantification of 4-HNE adducts was performed using a competitive ELISA kit (ab238538, Abcam, Cambridge, UK) following the manufacturer’s instructions. Absorbance at 450 nm was recorded

(12) A Pseudomonas aeruginosa quorum-sensing metabolite manipulates macrophage ferroptosis through a methylation pathwayNature CommunicationsNovember 13, 2025Tianyuan Jia, Fengming Li, Tianzhen Li, Anmin Ren, Peiyi Lu, Yiling Liu, Yachun Zhou, Xiangke Duan, Yang Liu, Lin Zhong, et al.Reader (Tecan). Lipid peroxidation (4-HNE) was detected by a commercial assay kit (Abcam, Cat Number#: ab238538). Thermal proteome profiling RAW264.7 cells were lysed in the CETSA lysis buffer, followed by the

(13) Hydrocolloid‐Based Multiwavelength Stretchable QD‐OLED Patch for Simultaneous Neonatal Jaundice and Dermatitis Treatment with Biosignal MonitoringAdvanced Healthcare MaterialsNovember 3, 2025In Ho Kim, Young Woo Kim, Jae‐Young Jeong, Ye Ji Shin, Chaeyeong Lee, Jae Gyun Choi, Oh Kwan Kwon, Kyoung Hwa Kim, Sang Jik Kwon, Eou‐Sik Cho, et al.Cell Viability and Proliferation Assay Cell proliferation was evaluated using the CCK‐8 assay kit (ab238538; Abcam Inc.). CCK‐8had low cytotoxicity and provided a convenient and sensitive colorimetric assay using

(14) HDAC3 knockdown inhibits ferroptosis via upregulating Nrf2 to alleviate renal interstitial fibrosis in lupus nephritisLupus Sci MedOctober 22, 2025Tianli Shi, Zhen Luo, Wenjuan Leiassessed using the relevant kit. Moreover, the ferroptosis marker levels of 4-hydroxynonenal (4-HNE, #ab238538, Abcam) and iron ions (#ab83366, Abcam) in cellular supernatant were detected by corresponding kits. Immunofluorescence

(15) Integrated Omics and Multi-Cohort Analyses Identify an Enhancer Variant Linking Ferroptosis to Precision Therapy in Prostate CancerCancer ResearchOctober 1, 2025Sheng Ma, Yue Ge, Zequn Lu, Junbiao Zhang, Qin Zhang, Yuzheng Peng, Zirui Xi, Hao Peng, Meng-Yao Xu, Zezhong Xiong, et al.marker of lipid peroxidation, using a validated commercial ELISA-based Lipid Peroxidation Assay Kit (ab238538, Abcam) according to the manufacturer’s optimized protocol. Briefly, approximately 1 mg of frozen tissue

(16) Induction of ferroptosis in prostate cancer by CCDC719-13 via TRIM21-mediated ubiquitination of SLC7A11Cell Death & DifferentiationSeptember 22, 2025Bisheng Cheng, Qiong Wang, Zean Li, Tianlong Luo, JunJia Xie, Sandeep Singh, Yong Luo, Xu Gao, Hui Li, Zongwei Wang, et al.were evaluated using commercially available detection kits: MDA (KTE61683, Abbkine, USA) and 4-HNE (ab238538, Abcam, UK). For the MDA assay, 2 × 10⁶ cells were disrupted in MDA lysis buffer containing 1% butylated

(17) Modulation of ferroptosis via YY1-SLC7A11 axis in hepatic ischemia-reperfusion injury pathogenesisActa Biochimica et Biophysica SinicaSeptember 1, 2025Shaochuang Wang, Baofei Jiang, Jun Cao, Ting Xu, Chengming Zhou, Xiangyou Yu, Yi Wang, Yu Xie, Lindong Ji, Guangrong Zhou, et al.China) was used to measure the MDA content in cells or tissues; a Lipid Peroxidation (4-HNE) Assay Kit (ab238538; Abcam) was used to detect the 4-HNE content in cells or tissues; and a GSH Assay Kit (Colorimetric)

(18) BCS1L ‐Associated Disease: 5′‐UTR Variant Shifts the Phenotype Towards Axonal NeuropathyAnnals of Clinical and Translational NeurologySeptember 1, 2025Rotem Orbach, Nunziata Maio, Russell J. Butterfield, A. Reghan Foley, Sarah Silverstein, Yan Li, Katherine Chao, Tanya J. Lehky, Abigail Potticary, Tracey A. Rouault, et al.paternal cells was assessed as follows: Lipid peroxidation was measured using the 4‐HNE assay kit (Abcam, #ab238538) and the MDA assay kit (colorimetric, Abcam, #ab118970), according to the manufacturer's instructions.

(19) A mitochondrial ferroptosis-related gene signature predicts prognosis and immune landscape in colon cancerFrontiers in MedicineSeptember 1, 2025Hou Wang(MDA) Assay Kit (Sigma-Aldrich, Cat #: MAK085), Lipid Peroxidation (4-HNE) Assay Kit (Abcam, Cat #: ab238538) and Iron Assay Kit (Sigma-Aldrich, Cat #: MAK025) according to the manufacturer’s instructions. Statistical

(20) Development of a bispecific CDH17-GUCY2C ADC bearing the ferroptosis inducer RSL3 for the treatment of colorectal cancerCell Death DiscovJuly 28, 2025Ying Zhang, Jing Du, Xiaohong Cui, Yuhang Ling, Chengwu Tangmeasured at 532 nm. Lipid peroxidation (4-HNE) assay Lipid Peroxidation (4-HNE) Assay Kit (Abcam, ab238538) were used to evaluate the concentration of 4-HNE according to the manufacturer’s protocol. Briefly,

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Lipid Peroxidation (4-HNE) Assay Kit from Abcam

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Lipid Peroxidation (4-HNE) Assay Kit from Abcam

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