Fig 2: RUNX3 expression is correlated with clinicopathological characteristics of SAP patients. (A–K) Correlations between RUNX3 expression in peripheral blood and CRP, PCT, LDH, AST, BUN, APACHE II score, Ranson score, BISAP score, SOFA score, and MCTSI score in 18 SAP patients were analyzed using Pearson correlation analysis. SAP, severe acute pancreatitis; PCT, procalcitonin; APACHE II, Acute Physiology and Chronic Health Evaluation II; BISAP, Bedside Index for Severity in Acute Pancreatitis; SOFA, sequential organ failure assessment; MCTSI, modified computed tomography severity index.

Fig 3: Performance of serum endocan, PCT, and IL-6 in the diagnosis of organ failures in hospitalized patients with cirrhosis (n = 116).The AUCs for the diagnosis of organ failures were 0.65 for serum endocan, 0.69 for serum PCT, and 0.67 for serum IL-6. The AUCs of all biomarkers were not significantly different (p = 0.84). AUC, area under the ROC curve; IL-6, interleukin-6; PCT, procalcitonin.

Fig 4: Correlation of miR-223-3p with inflammation and severity. a-d. correlation with inflammation indicators, CRP (a), PCT (b), IL-6 (c), NLR (d). e-f. correlation with severity indicators, BSI score (e), and FACED score (f)