Methylamp Methylated DNA Capture (MeDIP) Kit P-1015 from EpiGentek

Product Specs
ItemMethylamp Methylated DNA Capture (MeDIP) Kit
CompanyEpiGentek
Price Supplier Page View Company Product Page
Catalog NumberP-1015
Quantity24 Reactions, 48 Reactions
Sample TypeDNA
SourceCell/Tissue
Research AreaDNA Methylation
Nucleic Acid TypeMethylated DNA, ChIP DNA

EpiGentek

110 Bi County Blvd. Ste 122

Farmingdale, NY 11735

United States

Phone: 1 877 EPIGENTEK (374-4368)
International: 1 631 755-0888
Fax (General): 1 631 815-6729
Fax (Orders): 1 718 484-3956

Email: info@epigentek.com
sales@epigentek.com
services@epigentek.com
support@epigentek.com

Company Profile

Website: www.epigentek.com

(1) Ethanol Alters DNMT1/3a/3b Expression Profile, Promotes Persistent DNA Hypomethylation in Human Brain Endothelial Cells and Impairs Late Cortical AngiogenesisJ NeurochemFebruary 10, 2026Michele Siqueira, Matheus Barros, Paula Lacerda Almeida, Luiza Dos Santos Heringer, Henrique Rocha Mendonça, Flávia Carvalho Alcantara Gomes, Joice Stipurskyantibody to 5‐methylcytosine using the Methylamp Methylated DNA Capture kit (MeDIP; Epigentek, Cat. P‐1015‐48). Sonicated DNA not processed for MeDIP, was used as input DNA. The immunoprecipitated methylated

(2) Maternal Fructose Intake During Pregnancy Induced the Hepatic Glucose Homeostasis Imbalance in the Offspring by Inhibiting GlucokinaseThe FASEB JournalJanuary 31, 2026Yahui Miao, Ziyu Meng, Shihang Chen, Xiaoyu Li, Ting Fang, Xiaoqing Deng, Bei Sun, Liming Chencells. After 48 h, the MeDIP experiment was initiated using the Methylamp Methylated DNA Capture Kit (P‐1015, EpiGentek, USA). We used antibodies of IgG and 5‐mC to capture valid DNA fragments. Finally, the captured

(3) Lactate transmission from hypoxic tumor cells promotes macrophage senescence and M2 polarization via the DNMT1-NHE7 axis to accelerate endometrial cancer progressionCell Death & DiseaseJanuary 30, 2026Shizhou Yang, Yuejiang Ma, Tingting Wu, Xiufeng HuangDNA was enriched using the EpiQuik™ Methylated DNA Immunoprecipitation (MeDIP) Kit (Epigentek, USA, p-1015), and methylation levels were subsequently quantified by qPCR. The same procedures were applied to tumor

(4) Maternal Fructose Intake During Pregnancy Induced the Hepatic Glucose Homeostasis Imbalance in the Offspring by Inhibiting GlucokinaseFASEB JJanuary 23, 2026Yahui Miao, Ziyu Meng, Shihang Chen, Xiaoyu Li, Ting Fang, Xiaoqing Deng, Bei Sun, Liming Chencells. After 48 h, the MeDIP experiment was initiated using the Methylamp Methylated DNA Capture Kit (P‐1015, EpiGentek, USA). We used antibodies of IgG and 5‐mC to capture valid DNA fragments. Finally, the captured

(5) Mitochondrial Fragmentation and Long Noncoding RNA MALAT1 in Diabetic RetinopathyInt J Mol SciJuly 3, 2025Renu A. Kowluru, Jay Kumarbinding at the Mfn2 promoter. For 5mC quantification, the Methylamp™ Methylated DNA Capture Kit (Cat. No. P-1015-48, EPIGENTEK, Farmingdale, NY, USA) was used. Briefly, genomic DNA isolated from the cells using a

(6) DNA methylation of long noncoding RNA cytochrome B in diabetic retinopathyNon-coding RNA ResearchApril 1, 2025Renu A. Kowluru, Jay Kumar, Pooja Malaviyaapproval. 2.4 Quantification of 5 mC Using a methylated DNA immunoprecipitation kit from Epigentek (Cat no. P-1015-48; Epigentek, Farmingdale, NY, USA), 5 mC was quantified in the sonicated genomic DNA (100 ng) immunoprecipitated

(7) Diabetic Retinopathy and Regulation of Mitochondrial Glutathione–Glutathione Peroxidase Axis in HyperhomocysteinemiaAntioxidants (Basel)February 20, 2024Pooja Malaviya, Renu A. KowluruUSA), was incubated with 5mC antibodies to immunoprecipitate 5mC-enriched DNA (MeDIP kit, Cat. No. P-1015, EPIGENTEK, Farmingdale, NY, USA), and 5mC at the GPx1 promoter was quantified by qRT-PCR [23]. DNA methylation

(8) Faulty homocysteine recycling in diabetic retinopathyEye and VisionDecember 1, 2020Renu A. Kowluru, Ghulam Mohammad, Nikhil Sahajpal5mC. The levels of 5mC were quantified using methylated DNA Immunoprecipitation (MeDIP) kit (Cat. No. P-1015, EPIGENTEK, Farmingdale, NY, USA) [30]. The enrichment of 5mC at the promoters of CBS and MTHFR was

(9) Retinopathy in a Diet-Induced Type 2 Diabetic Rat Model and Role of Epigenetic ModificationsDiabetesApril 1, 2020Renu A. Kowlurugenomic DNA using EpiQuik methylated and hydroxymethylated DNA Immunoprecipitation Kits (catalog numbers P-1015 and P-1038, respectively, from EpiGentek, Farmingdale, NY), as described previously (19,24). The binding

(10) Homocysteine Disrupts Balance between MMP-9 and Its Tissue Inhibitor in Diabetic Retinopathy: The Role of DNA MethylationInternational journal of molecular sciencesMarch 5, 2020Mohammad G, Kowluru RA.quantified in the total genomic DNA by MethyLamp Methylated and Hydroxymethylated DNA capture Kits (Cat. No. P-1015 and Cat. No. P-1038 respectively, EPIGENTEK), as reported previously [45,46], using the primers targeting

(11) Epigenetic Modifications in Peripheral Blood as Potential Noninvasive Biomarker of Diabetic RetinopathyTranslational Vision Science & TechnologyDecember 18, 2019Arul J. Duraisamy, Rakesh Radhakrishnan, Berhane Seyoum, Gary W. Abrams, Renu A. Kowlurumethylated and hydroxymethylated DNA immunoprecipitation kits (MeDIP and hMeDIP kits respectively, Cat. No. P-1015, P-1038; EpiGentek, Farmingdale, NY). Using 250 ng gDNA for 5mC and 500 ng for 5hmC, DNA bound to the

(12) Epigenetic Modifications Compromise Mitochondrial DNA Quality Control in the Development of Diabetic RetinopathyInvestigative ophthalmology & visual scienceSeptember 3, 2019Mohammad G, Radhakrishnan R, Kowluru RA.(5mC) were quantified in the total genomic DNA by a MethyLamp Methylated DNA capture kit (cat. no. P-1015, EPIGENTEK, Farmingdale, NY, USA)31 using Mlh1 promoter primers (Table 2). Gene Expression Gene transcripts

(13) Early Parity Epigenetic Footprint of FOXA1 Gene Body in Normal Breast Tissue of Iranian WomenIranian Biomedical JournalMarch 1, 2019Zahra Zendehbad, Department of Medical Genetics, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran, Pantea Izadi, Department of Medical Genetics, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran, Abdolreza Daraei, Genetic Department, Faculty of Medicine, Babol University of Medical Sciences, Babol, Iran, Mir Saeed Yekaninejad, Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran, Nahid Nafissi, Surgical Department, School of Medicine, Iran University of Medical Science, Tehran, Iran, et al.qPCR MeDIP was carried out using MethylampTM Methylated DNA capture kit )Epigentek, USA, Cat. No # P-1015). After extraction, DNA (1 μg) was sheared by sonication to obtain fragments ranging from 200 to 1000

(14) Early Parity Epigenetic Footprint of FOXA1 Gene Body in Normal Breast Tissue of Iranian WomenIranian Biomedical JournalMarch 1, 2019Zahra Zendehbad, Pantea Izadi, Abdolreza Daraei, Mir Saeed Yekaninejad, Nahid Nafissi, Nasim Younosi, Ghasemali Khorasani, Javad Tavakkoly Bazzaz, Department of Medical Genetics, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran, Department of Medical Genetics, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran, et al.qPCR MeDIP was carried out using MethylampTM Methylated DNA capture kit )Epigentek, USA, Cat. No # P-1015). After extraction, DNA (1 μg) was sheared by sonication to obtain fragments ranging from 200 to 1000

(15) Epigenetics and Regulation of Oxidative Stress in Diabetic RetinopathyInvestigative ophthalmology & visual scienceOctober 1, 2018Duraisamy AJ, Mishra M, Kowluru A, Kowluru RA.methylated or hydroxymethyldated DNA Immunoprecipitation (MeDIP)/(hMeDIP) kits, respectively (Cat. Nos. P-1015 and P-1038, respectively; EPIGENTEK, Farmingdale, NY, USA). The enrichment of 5mC or 5hmC at the Rac1

(16) Detection of fetal epigenetic biomarkers through genome-wide DNA methylation study for non-invasive prenatal diagnosisMolecular Medicine ReportsJune 1, 2017Hong-Dan Wang, Lin Liu, Hui-Ru Zhao, Qiao-Fang Hou, Jing-Bin Yan, Wei-Li Shi, Qian-Nan Guo, Li Wang, Shi-Xiu Liao, Bo-Feng Zhureference in all experiments. Methylated DNA (mDNA) capture The Methylamp Methylated DNA Capture kit (P-1015; EpiGentek Group, Inc., Farmingdale, NY, USA) was used to enrich and capture methylated DNA fragments

(17) The Role of DNA Methylation in the Metabolic Memory Phenomenon Associated With the Continued Progression of Diabetic RetinopathyInvestigative Opthalmology & Visual ScienceOctober 27, 2016Manish Mishra, Renu A. Kowlurung), which was immunoprecipitated for 5mC by methylated DNA immunoprecipitation kit from Epigentek (P-1015–48; Epigentek, Farmingdale, NY, USA). The enriched 5mC fraction was analyzed for mtDNA (D-loop region)

(18) High inorganic phosphate causes DNMT1 phosphorylation and subsequent fibrotic fibroblast activationBiochemical and biophysical research communicationsApril 8, 2016Tan X, Xu X, Zeisberg EM, Zeisberg M.

(19) DNMT1 and HDAC2 Cooperate to Facilitate Aberrant Promoter Methylation in Inorganic Phosphate-Induced Endothelial-Mesenchymal TransitionPloS oneJanuary 1, 2016Tan X, Xu X, Zeisberg M, Zeisberg EM.

(20) Sex-Dependent effects of developmental arsenic exposure on methylation capacity and methylation regulation of the glucocorticoid receptor system in the embryonic mouse brainToxicology reportsOctober 1, 2015Allan AM, Hafez AK, Labrecque MT, Solomon ER, Shaikh MN, Zheng X, Ali A.Qubit® 2.0 Fluorometer. MeDIP was conducted using the Epigentek Methylamp Methylated DNA Capture (MeDIP) Kit (cat #: P-1015-24; Farmingdale, NY). 2 μg of gDNA from each sample was fragmented with a Kontes Micro Ultrasonic Cell

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Methylamp Methylated DNA Capture (MeDIP) Kit

Methylamp Methylated DNA Capture (MeDIP) Kit from EpiGentek

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Methylamp Methylated DNA Capture (MeDIP) Kit from EpiGentek

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