EpiQuik HAT Activity/Inhibition Assay Kit P-4003 from EpiGentek

Product Specs
ItemEpiQuik HAT Activity/Inhibition Assay Kit
CompanyEpiGentek
Price Supplier Page View Company Product Page
Catalog NumberP-4003
Quantity48 Assays, 96 Assays
Sample TypeNuclear Extracts, Purified Enzyme
Research AreaHistone Acetylation

EpiGentek

110 Bi County Blvd. Ste 122

Farmingdale, NY 11735

United States

Phone: 1 877 EPIGENTEK (374-4368)
International: 1 631 755-0888
Fax (General): 1 631 815-6729
Fax (Orders): 1 718 484-3956

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Company Profile

Website: www.epigentek.com

(1) Epigenetically driven impairment of BDNF-ARC signaling contributes to circadian and cognitive disarray in a mouse model of postoperative deliriumAlzheimers DementJune 15, 2026Hari Prasad Osuru, Navya Atluri, Tam Le, Jinny Park, Michal Jedrusiak, Elzbieta Dulko, Meghana Illendula, Nadia Lunardiextract was used per assay. HAT activity was measured using the Epigentek HAT Activity Assay Kit (Cat#P‐4003), and HDAC activity was measured using the HDAC Activity Assay Kit (Cat#P‐4034), both from Epigentek

(2) The noncanonical function of liver-type phosphofructokinase potentiates the efficacy of HDAC inhibitors in cancerSignal Transduct Target TherOctober 14, 2025Taiyu Shang, Tianyi Jiang, Jiangqi Tan, Haolin Jiang, Mengyou Xu, Yufei Pan, Yunkai Lin, Xiaowen Cui, Chenxi Tian, Huibo Feng, et al.kit (TD903) were purchased from Vazyme Biotech. Histone Acetyltransferase (HAT) activity assay kit (P-4003-96) was purchased from EpigenTek. Histone Deacetylase (HDAC) activity assay kit (AAT-13601) was purchased

(3) Targeting histone acetylation to enhance somatic embryogenesis in Quercus suber L.Tree PhysiologyOctober 1, 2025Natalia E De-la-Paz, Elena Carneros, Beatriz Pintos, Pilar S Testillanohistone H4 acetylation dynamics in cork oak SE progression, an EpiQuik HAT Activity/Inhibition Assay Kit (P-4003, Epigentek) was used according to the manufacturer’s instructions. Around 100 mg of each sample were

(4) Stress during puberty and adulthood pregnancy impact histone acetylation regulators in the hypothalamusNeuroscienceMay 14, 2025Laiklyn A.M. Luther, Samantha L. Higley, Kathleen E. Morrisonquantification HAT activity was measured using the EpiQuik HAT Activity/Inhibition Assay Kit (Epigentek, P-4003). HDAC activity was measured using the Epigenase HDAC Activity/Inhibition Direct Assay Kit (Epigentek,

(5) Viscoelastic extracellular matrix enhances epigenetic remodeling and cellular plasticityNat CommunApril 30, 2025Yifan Wu, Yang Song, Jennifer Soto, Tyler Hoffman, Xiao Lin, Aaron Zhang, Siyu Chen, Ramzi N. Massad, Xiao Han, Dongping Qi, et al.HDAC, H3K4 HMT, and H3K4 HDM activity were measured using the HAT activity/inhibition assay (EpiGentek, P-4003-048), HDAC activity/inhibition assay (EpiGentek, P-4034-096), HMT (H3K4 specific) activity/inhibition

(6) The Nuclear Receptor NR1B1/RARα Arrests the Differentiation of Anti‐Tumor Effector Cytotoxic T CellsAdvanced ScienceMarch 11, 2025Patrick Niekamp, Ryun Hee Kim, Adithyan Jayaraman, Nils Klement, Raymond Kostlan, Chang H. Kimand total HAT activity was measured using EpiQuik HAT Activity/Inhibition Assay Kit (Epigentek, Cat# P‐4003‐96). Adoptive T‐Cell Transfer into Rag1‐KO Mice Bearing Tumors Rag1‐KO mice were injected subcutaneously

(7) Leishmania mexicana N‐Acetyltransferease 10 Is Important for Polysome Formation and Cell Cycle ProgressionMolecular MicrobiologyJanuary 4, 2025Suellen Rodrigues Maran, Ariely Barbosa Leite, Gabriela Gomes Alves, Bruno Souza Bonifácio, Carlos Eduardo Alves, Paulo Otávio Lourenço Moreira, Giovanna Marques Panessa, Heloísa Monteiro do Amaral Prado, Angélica Hollunder Klippel, José Renato Cussiol, et al.acetyltransferase activity assay, we used the EpiQuik™ HAT Activity/Inhibition Assay Kit (EpigenTek #P-4003), which was designed to measure the activity of histone acetylases (HAT). For each assay we used 10

(8) New Inhibitors of the Human p300/CBP Acetyltransferase Are Selectively Active against the Arabidopsis HAC ProteinsInternational Journal of Molecular SciencesSeptember 9, 2022Chiara Longo et al.The partially purified 52 kDa protein was used for an acetyltransferase activity assay (EpiGentek # P-4003). The results shown in Figure 8 reveal that compound 2c inhibits acetylase activity of the HAC1 protein.

(9) Enriched environment causes epigenetic changes in hippocampus and improves long-term cognitive function in sepsisScientific reportsJuly 7, 2022Córneo E, Michels M, Abatti M, Vieira A, Gonçalves RC, Gabriel FF, Borges H, Goulart A, da Silva Matos N, Dominguini D, et al.assay kit (colorimetric detection) according to the manufacturer's instructions (Epigentek cod. HAT P-4003-96; HDAC P-4002-96; DNMT P-3001-2). A standard curve was performed with serial dilutions of subtracts

(10) Luteolin Causes 5′CpG Demethylation of the Promoters of TSGs and Modulates the Aberrant Histone Modifications, Restoring the Expression of TSGs in Human Cancer CellsInternational Journal of Molecular SciencesApril 6, 2022Sreepoorna Pramodh, Ritu Raina, Arif Hussain, Sali Abubaker Bagabir, Shafiul Haque, Syed Tasleem Raza, Mohammad Rehan Ajmal, Shalini Behl, Deepika Bhagavatulaof 3 experiments ± SD (p ≤ 0.05). 4.11. HAT Activity HAT activity/inhibition kit (catalogue number P-4003, Epigentek, NY, USA) was procured. Briefly, the nuclear extracts were incubated with the substrate for

(11) A Src-H3 acetylation signaling axis integrates macrophage mechanosensation with inflammatory responseBiomaterialsDecember 1, 2021Veerasubramanian PK, Shao H, Meli VS, Phan TAQ, Luu TU, Liu WF, Downing TL.flats. 2.12. HAT activity assay Total HAT activity was measured using a colorimetric kit (Epigentek, Cat. P-4003-96), following the manufacturer’s recommended protocol. Nuclear extracts from 5 × 106 cells collected

(12) Acute high folic acid treatment in SH-SY5Y cells with and without MTHFR function leads to gene expression changes in epigenetic modifying enzymes, changes in epigenetic marks, and changes in dendritic spine densitiesPLOS ONEJanuary 7, 2021Daniel F. Clark, Rachael Schmelz, Nicole Rogers, Nuri E. Smith, Kimberly R. Shorterassays from Epigentek for DNMTs (Cat. No. P-3009-48), HMTs (H3K4) (Cat. No. P-3002-1), HATs (Cat. No. P-4003-48), TETs (Cat. No. P-3086-48), and HDACs (Cat. No. P-4034-48) were used. Nuclear extracts were loaded

(13) Therapeutic effectiveness of a single exercise session combined with WalkAide functional electrical stimulation in post-stroke patients: a crossover design studyNeural Regeneration ResearchJanuary 1, 2021Viviane Rostirola Elsner, Lucieli Trevizol, Isadora de Leon, Marcos da Silva, Thayná Weiss, Milena Braga, Daniela Pochmann, Amanda Stolzenberg Blembeel, Caroline Dani, Elenice Boggioaccording to the manufacturer’s protocol (Epigentek, Madrid, Spain: P-4006: EpiQuik HDAC2 assay kit; P-4003: EpiQuik HAT activity/ inhibition assay kit, respectively).The Coomassie Blue method (Bradford, 1976)

(14) Pulsed glucocorticoids enhance dystrophic muscle performance through epigenetic-metabolic reprogrammingJCI insightDecember 19, 2019Quattrocelli M, Zelikovich AS, Jiang Z, Peek CB, Demonbreun AR, Kuntz NL, Barish GD, Haldar SM, Bass J, McNally EM.by anacardic acid in tissues was monitored using the HAT activity colorimetric dosing assay (catalog P-4003; Epigentek). Sterile BD Micro-Fine IV Insulin Syringes (14-829-1A; Thermo Fisher Scientific) were used

(15) Nuclear S-Nitrosylation Defines an Optimal Zone for Inducing PluripotencyCirculationSeptember 24, 2019Chanda PK, Meng S, Lee J, Leung HE, Chen K, Cooke JP.on day 4, and HDAC1/2 activity was measured for each sample following the manufacturer’s (Epigentek, P-4003) protocol. Nuclear proteins (5 µg) from each sample were used for the assay. S-Nitrosylation Mediates

(16) Enriched gestation activates the IGF pathway to evoke embryo-adult benefits to prevent Alzheimer's diseaseTranslational neurodegenerationJanuary 1, 2019Liu E, Zhou Q, Xie AJ, Li M, Zhang S, Huang H, Liuyang Z, Wang Y, Liu B, Li X, et al.20 s. HAT and HDAC activity assays The activity of HAT was assayed using a HAT activity assay kit (p-4003, Epigentek, NY, USA), and the activity of HDACs was assayed using a HDAC activity assay kit (P-4034,

(17) Reduced PPARγ2 expression in adipose tissue of male rat offspring from obese dams is associated with epigenetic modificationsFASEB journal : official publication of the Federation of American Societies for Experimental BiologyMay 1, 2018Lecoutre S, Pourpe C, Butruille L, Marousez L, Laborie C, Guinez C, Lesage J, Vieau D, Eeckhoute J, Gabory A, et al.Activity 243 Quantification kit (Cat # ab156912; Abcam, Cambridge, UK), EpiQuick HAT Assay kit (Cat 244 # P-4003-96; Epigentek, Mundolsheim, France) and EpiQuick HDAT Assay kit (Cat # P- 245 4002-96; Epigentek,

(18) HDAC1 and HDAC3 underlie dynamic H3K9 acetylation during embryonic neurogenesis and in schizophrenia-like animalsJournal of cellular physiologyJanuary 1, 2018Večeřa J, Bártová E, Krejčí J, Legartová S, Komůrková D, Rudá-Kučerová J, Štark T, Dražanová E, Kašpárek T, Šulcová A, et al.Activity/Inhibition Assay kit (Epigentek, represented by Epigentek, represented by Lab Mark, Czech Republic, #P-4003-48) and EpiQuick HDAC Activity/Inhibition Assay kit (Epigentek, represented by Lab Mark, #P-4002-48).

(19) Quetiapine treatment reverses depressive-like behavior and reduces DNA methyltransferase activity induced by maternal deprivationBehavioural Brain ResearchMarch 1, 2017Zuleide M. Ignácio et al.extract samples were mixed with HDAC (EPIGENTEK; Base catalog #P-4034), HAT (EPIGENTEK; Base catalog #P-4003) or DNMT (EPIGENTEK; Base catalog #P3009) assay buffer, more assay substrate of the same enzymes, in a

(20) Histone deacetylation contributes to low extracellular superoxide dismutase expression in human idiopathic pulmonary arterial hypertensionAmerican Journal of Physiology-Lung Cellular and Molecular PhysiologyJuly 1, 2016Eva Nozik-Grayck et al.

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EpiQuik HAT Activity/Inhibition Assay Kit

EpiQuik HAT Activity/Inhibition Assay Kit from EpiGentek

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EpiQuik HAT Activity/Inhibition Assay Kit from EpiGentek

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