NLRP3 ELISA Kit (Human) (OKEH03368) from Aviva Systems Biology

Product Specs
ItemNLRP3 ELISA Kit (Human) (OKEH03368)
CompanyAviva Systems Biology
Price $525.00Supplier Page View Company Product Page
Catalog NumberOKEH03368
Quantity96T
ApplicationsELISA-Sandwich
DetectionColorimetric, OD450 nm
ReactivityHomo sapiens, Human
Sample TypeSerum, Plasma, Tissue Homogenates, Cell Culture Supernates, Other Biological Fluids
Detection TargetQ96P20
Assay Time~ 3 Hours
NCBI Gene AliasesMWS, AGTAVPRL, CLR1.1, CIAS1, FCU, FCAS, C1orf7, AVP, KEFH, DFNA34, NALP3, AII, FCAS1, PYPAF1
Sensitivity0.078 ng/mL
Molecular Weight118 kDa
Detection Range0.156-10ng/mL
Gene NameNLR family pyrin domain containing 3
ComponentsStop Solution
Anti-NLRP3 Microplate
Conjugate Diluent
Sample Diluent
Detector Antibody Diluent
100X Avidin-HRP Conjugate
NLRP3 Lyophilized Standard
25X Wash Buffer
100X Biotinylated NLRP3 Detector Antibody
TMB Substrate
YieldMean recovery when spiking into sample matrices at concentrations within the dynamic range: 96%

Specifications/Features

Specificity: Natural and recombinant Human NACHT, LRR and PYD domains-containing protein 3

Add to Compare List

Aviva Systems Biology

5754 Pacific Center Blvd

Suite 201

San Diego, California 92121

United States

Phone: Toll Free: +1-888-880-0001
858-552-6979

Company Profile

Website: http://www.avivasysbio.com/

(1) SGLT2 Inhibitor Dapagliflozin Attenuates Cardiomyocyte Injury and Inflammation Induced by PI3Kα-Selective Inhibitor Alpelisib and Fulvestrant Under HyperglycemiaInt J Mol SciApril 17, 2026Vincenzo Quagliariello, Massimiliano Berretta, Matteo Barbato, Fabrizio Maurea, Maria Laura Canale, Andrea Paccone, Irma Bisceglia, Andrea Tedeschi, Marino Scherillo, Jacopo Santagata, et al.Intracellular Inflammasome-Related Proteins Intracellular levels of NLRP3 (Human NLRP3 ELISA Kit (OKEH03368), Aviva Systems Biology, San Diego, CA, USA) and MyD88 (Human MyD88 ELISA Kit (ab171341), Abcam, Milan,

(2) Evidence of Cardiotoxic Immune Activation by Triple Immune Checkpoint Blockade: A Translational Alert for Clinical Surveillance in Patients With CancerJournal of Cardiovascular PharmacologyApril 1, 2026Vincenzo Quagliariello, Margherita Passariello, Martina Belardo, Assunta Esposito, Miriam Paone, Massimiliano Berretta, Martina Iovine, Matteo Barbato, Maria Laura Canale, Andrea Paccone, et al.NF-κB (p65) was quantified with specific ELISA kits. In detail, we used antihuman NLRP3 ELISA kit (code OKEH03368; Aviva Systems Biology, San Diego, CA; sensitivity: 0.078 ng/mL), antihuman MyD88 ELISA kit (My Biosource,

(3) Evidence of Cardiotoxic Immune Activation by Triple Immune Checkpoint Blockade: A Translational Alert for Clinical Surveillance in Patients With CancerJ Cardiovasc PharmacolMarch 15, 2026Vincenzo Quagliariello, Margherita Passariello, Martina Belardo, Assunta Esposito, Miriam Paone, Massimiliano Berretta, Martina Iovine, Matteo Barbato, Maria Laura Canale, Andrea Paccone, et al.NF-κB (p65) was quantified with specific ELISA kits. In detail, we used antihuman NLRP3 ELISA kit (code OKEH03368; Aviva Systems Biology, San Diego, CA; sensitivity: 0.078 ng/mL), antihuman MyD88 ELISA kit (My Biosource,

(4) PCSK9 Inhibitor Inclisiran Attenuates Cardiotoxicity Induced by Sequential Anthracycline and Trastuzumab Exposure via NLRP3 and MyD88 Pathway InhibitionInternational journal of molecular sciencesJuly 10, 2025Quagliariello V, Berretta M, Bisceglia I, Iovine M, Barbato M, Arianna R, Canale ML, Paccone A, Inno A, Scherillo M, et al.enzyme-linked immunosorbent assays (ELISA) specific for human MyD88 (ab171341, Abcam, Milan, Italy) and human NLRP3 (OKEH03368, Aviva Systems Biology, San Diego, CA, USA), in accordance with established protocols [46]. Briefly,

(5) Hyaluronic Acid-Based Nanoparticles Loaded with Rutin as Vasculo-Protective Tools against Anthracycline-Induced Endothelial DamagesPharmaceuticsJuly 25, 2024Carla Serri, Vincenzo Quagliariello, Iriczalli Cruz-Maya, Vincenzo Guarino, Nicola Maurea, Paolo Giunchedi, Giovanna Rassu, Elisabetta Gavinicentrifuged supernatants and were used for the quantification of NLRP-3 through an NLRP-3 ELISA Kit (code OKEH03368, Aviva Systems Biology, San Diego, CA, USA) and MyD-88 through a MyD-88 ELISA Kit (code ab171341, Abcam,

(6) Sodium-glucose cotransporter 2 inhibitor dapagliflozin prevents ejection fraction reduction, reduces myocardial and renal NF-κB expression and systemic pro-inflammatory biomarkers in models of short-term doxorubicin cardiotoxicityFrontiers in Cardiovascular MedicineMay 16, 2024V. Quagliariello, M. L. Canale, I. Bisceglia, M. Iovine, A. Paccone, C. Maurea, M. Scherillo, A. Merola, V. Giordano, G. Palma, et al.of MyD88 [Human MyD88 ELISA Kit (ab171341); Abcam, Milan, Italy] and NLRP3 [Human NLRP3 ELISA Kit (OKEH03368); Aviva Systems Biology, San Diego, CA, USA]. For the human MyD88 ELISA, the sensitivity was <10 pg/ml

(7) The sGCa Vericiguat Exhibit Cardioprotective and Anti-Sarcopenic Effects through NLRP-3 Pathways: Potential Benefits for Anthracycline-Treated Cancer PatientsCancersApril 12, 2024Quagliariello V, Berretta M, Bisceglia I, Giacobbe I, Iovine M, Giordano V, Arianna R, Barbato M, Izzo F, Maurea C, et al.myeloid differentiation response 88 (Myd-88) cellular levels were measured using human NLRP-3 ELISA Kit (OKEH03368, Aviva Systems Biology, San Diego, CA, USA) and human MyD88 ELISA Kit (ab171341, Abcam, Milan, Italy)

(8) Combinatorial immune checkpoint blockade increases myocardial expression of NLRP-3 and secretion of H-FABP, NT-Pro-BNP, interleukin-1β and interleukin-6: biochemical implications in cardio-immuno-oncologyFrontiers in cardiovascular medicineJanuary 1, 2024Quagliariello V, Passariello M, Bisceglia I, Paccone A, Inno A, Maurea C, Rapuano Lembo R, Manna L, Iovine M, Canale ML, et al.inhibitor). Cell lysates were centrifuged and supernatants were analyzed through NLRP-3 ELISA Kit (code OKEH03368; Aviva Systems Biology, San Diego, CA, USA) in line with manufacturer's instructions (31). Control group

(9) The perioperative effect of anesthetic drugs on the immune response in total intravenous anesthesia in patients undergoing minimally invasive gynecological surgeryRomanian Journal of Morphology and EmbryologyJune 10, 2022Marius Bogdan Novac et al.wavelength. Specifically-designed commercial test kits were used for each of the mediators: NLRP3 (Cat# OKEH03368, assay range: 0.312–20 ng/mL) – Aviva Systems Biology, San Diego, USA; TNF-α (Cat# BMS223-4, assay range:

(10) The perioperative effect of anesthetic drugs on the immune response in total intravenous anesthesia in patients undergoing minimally invasive gynecological surgeryRom J Morphol EmbryolMay 9, 2022Marius Bogdan Novac, Lidia Boldeanu, Luciana Teodora Rotaru, Anda Lorena Dijmărescu, Mircea-Sebastian Şerbănescu, Lucreţiu Radu, Simona Daniela Neamţu, Alina Maria Vîlcea, Mihaela Niculescu, Cecil Sorin Mirea, et al.wavelength. Specifically-designed commercial test kits were used for each of the mediators: NLRP3 (Cat# OKEH03368, assay range: 0.312–20 ng/mL) – Aviva Systems Biology, San Diego, USA; TNF-α (Cat# BMS223-4, assay range:

(11) NLRP3 Inflammasome Expression in Gingival Crevicular Fluid of Patients with Periodontitis and Chronic Hepatitis CMediators of InflammationNovember 19, 2021Petra Surlin, Luminita Lazar, Cerasella Sincar, Dorin Nicolae Gheorghe, Dora Maria Popescu, Virgil Mihail Boldeanu, Allma Pitru, Cristina Florescu, Ion Rogoveanuwas used. Specifically designed commercial test kits were used for each of the mediators, (i) NLRP3—OKEH03368 (Aviva Systems Biology, San Diego, USA) (range 0.312-20 ng/mL), (ii) CASP1—OKEH01146 (Aviva Systems Biology

(12) Polydatin Reduces Cardiotoxicity and Enhances the Anticancer Effects of Sunitinib by Decreasing Pro-Oxidative Stress, Pro-Inflammatory Cytokines, and NLRP3 Inflammasome ExpressionFrontiers in oncologyJanuary 1, 2021Quagliariello V, Berretta M, Buccolo S, Iovine M, Paccone A, Cavalcanti E, Taibi R, Montopoli M, Botti G, Maurea N.Kit (ab171341), Abcam, Milan, Italy; NLRP3 inﬂammasome was quantiﬁed through Human and rat NLRP3 ELISA Kit (OKEH03368), Aviva Systems Biology, San Diego, CA, USA) (35–37). Brieﬂy, an antibody against NLRP3 or MyD88 was

(13) NLRP3 as Putative Marker of Ipilimumab-Induced Cardiotoxicity in the Presence of Hyperglycemia in Estrogen-Responsive and Triple-Negative Breast Cancer CellsInternational journal of molecular sciencesOctober 21, 2020Quagliariello V, De Laurentiis M, Cocco S, Rea G, Bonelli A, Caronna A, Lombari MC, Conforti G, Berretta M, Botti G, et al.of MyD88 (Human MyD88 ELISA Kit (ab171341), Abcam, Milan, Italy) and NLRP3 (Human NLRP3 ELISA Kit (OKEH03368), Aviva Systems Biology, San Diego, CA, USA) [88,89]. Briefly, an antibody against NLRP3 or MyD88 was

(14) Evidences of CTLA-4 and PD-1 Blocking Agents-Induced Cardiotoxicity in Cellular and Preclinical ModelsJournal of personalized medicineOctober 19, 2020Quagliariello V, Passariello M, Rea D, Barbieri A, Iovine M, Bonelli A, Caronna A, Botti G, De Lorenzo C, Maurea N.(described before). Lysates were centrifuged and supernatants were treated with an NLRP3 ELISA Kit (OKEH03368) (Aviva Systems Biology, San Diego, CA, USA) [23] or a Myeloid differentiation primary response protein MyD88

Be the First to Write a Review!