PTEN HDR Plasmid (h) cDNA from Santa Cruz Biotechnology, Inc.

Product Specs
ItemPTEN HDR Plasmid (h) cDNA
CompanySanta Cruz Biotechnology, Inc.
Price $437.00Supplier Page View Company Product Page
Catalog Numbersc-400103-HDR
Quantity20 µg
TypePlasmid
Specieshuman
NCBI Full Gene Namephosphatase and tensin homolog
NCBI Gene Aliases10q23del, BZS, CWS1, DEC, GLM2, MHAM, MMAC1, PTEN1, PTENbeta, TEP1

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Neratinib, a pan ERBB/HER inhibitor, restores sensitivity of PTEN-null, BRAFV600E melanoma to BRAF/MEK inhibitionFrontiers in OncologyMay 16, 2024Evan DuBose, Samantha M. Bevill, Dana K. Mitchell, Noah Sciaky, Brian T. Golitz, Shelley A. H. Dixon, Steven D. Rhodes, James E. Bear, Gary L. Johnson, Steven P. Angusshown. CRISPR/Cas9-mediated deletion of PTEN CRISPR/PTEN KO plasmid (sc-400103) and PTEN HDR plasmid (sc-400103-HDR) pools were purchased from Santa Cruz. 2 μg of each plasmid was transfected into A375 cells using jetPRIME

(2) Interrogating glioma-M2 macrophage interactions identifies Gal-9/Tim-3 as a viable target against PTEN-null glioblastomaScience advancesJuly 8, 2022Ni X, Wu W, Sun X, Ma J, Yu Z, He X, Cheng J, Xu P, Liu H, Shang T, et al.

(3) PERK mediates resistance to BRAF inhibition in melanoma with impaired PTENNPJ precision oncologyJuly 19, 2021Qin Y, Zuo Q, Huang L, Huang L, Merlino G, Yu Y.knockout vector (cat# sc-400103) and the specific PTEN homology-directed repair PTEN–HDR vector (cat# sc-400103-HDR) for humans were purchased from Santa Cruz (Dallas, TX) directedly to knockout the PTEN gene specifically.

(4) Nanomedicines blocking adaptive signals in cancer cells overcome tumor TKI resistanceJournal of controlled release : official journal of the Controlled Release SocietyMay 10, 2020Kinoh H, Shibasaki H, Liu X, Yamasoba T, Cabral H, Kataoka K.

(5) DJ-1-binding compound B enhances Nrf2 activity through the PI3-kinase-Akt pathway by DJ-1-dependent inactivation of PTENBrain researchFebruary 15, 2020Niki T, Endo J, Takahashi-Niki K, Yasuda T, Okamoto A, Saito Y, Ariga H, Iguchi-Ariga SMM.

(6) ΜicroRNA-221 participates in cerebral ischemic stroke by modulating endothelial cell function by regulating the PTEN/PI3K/AKT pathwayExperimental and therapeutic medicineJanuary 1, 2020Peng H, Yang H, Xiang X, Li S.

(7) Symbiotic Macrophage-Glioma Cell Interactions Reveal Synthetic Lethality in PTEN-Null GliomaCancer cellJune 10, 2019Chen P, Zhao D, Li J, Liang X, Li J, Chang A, Henry VK, Lan Z, Spring DJ, Rao G, et al.

(8) PTEN inactivation induces epithelial-mesenchymal transition and metastasis by intranuclear translocation of β-catenin and snail/slug in non-small cell lung carcinoma cellsLung cancer (Amsterdam, Netherlands)April 1, 2019Perumal E, So Youn K, Sun S, Seung-Hyun J, Suji M, Jieying L, Yeun-Jun C.

(9) PTEN-induced partial epithelial-mesenchymal transition drives diabetic kidney diseaseThe Journal of clinical investigationMarch 1, 2019Li Y, Hu Q, Li C, Liang K, Xiang Y, Hsiao H, Nguyen TK, Park PK, Egranov SD, Ambati CR, et al.

(10) Dipeptidyl peptidase IV (DPP-4) inhibition alleviates pulmonary arterial remodeling in experimental pulmonary hypertensionLaboratory investigation; a journal of technical methods and pathologyOctober 1, 2018Xu J, Wang J, He M, Han H, Xie W, Wang H, Kong H.

(11) Paeonol enhances the sensitivity of human ovarian cancer cells to radiotherapy-induced apoptosis due to downregulation of the phosphatidylinositol-3-kinase/Akt/phosphatase and tensin homolog pathway and inhibition of vascular endothelial growth factorExperimental and therapeutic medicineOctober 1, 2017Zhou HM, Sun QX, Cheng Y.

(12) Synthetic essentiality of chromatin remodelling factor CHD1 in PTEN-deficient cancerNatureFebruary 23, 2017Zhao D, Lu X, Wang G, Lan Z, Liao W, Li J, Liang X, Chen JR, Shah S, Shang X, et al.

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