pGL4.47[luc2P/SIE/Hygro] Vector from Promega

Product Specs
ItempGL4.47[luc2P/SIE/Hygro] Vector
CompanyPromega
Price Supplier Page View Company Product Page
Catalog NumberE4041
Quantity20microg
Molecular Weight~44kDa
Nucleic Acid TypeReporter Vectors
Expression System (standardized)Mammalian
Vector NamepGL4.47[luc2P/SIE/Hygro]

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Promega

2800 Woods Hollow Rd

Madison, WI 53711

United States

Phone: Tel: +1 (608) 274-4330
Fax: +1 (608) 277-2516

Email: custserv@promega.com
techserv@promega.com

Company Profile

Website: http://www.promega.com

(1) Impaired cAMP–PKA–CREB1 signalling drives mitochondrial dysfunction in skeletal muscle during cancer cachexiaNature MetabolismNovember 12, 2025Elia Angelino, Lorenza Bodo, Roberta Sartori, Valeria Malacarne, Beatrice D’Anna, Nicolò Formaggio, Suvham Barua, Tommaso Raiteri, Andrea Lauria, Simone Reano, et al.(CRE-Luciferase reporter) (Promega; E847A) or STAT3 reporter vector (pGL4.47[luc2P/SIE/Hygro]; Promega; E4041) or NF-κB (pGL4.32[luc2P/NF-kB-RE/Hygro]; Promega; E8491) and pRL-null Vector (Renilla Luciferase Control

(2) Exploring Boswellia serrata Triterpenes: A New Frontier in Leukemia Inhibitory Factor Receptor ModulationACS OmegaMay 21, 2025Claudia Finamore, Carmen Festa, Mattia Cammarota, Lucio Spinelli, Elva Morretta, Chiara Cassiano, Maria Chiara Monti, Silvia Marchianò, Carmen Massa, Federica Moraca, et al.day-1, cells were transiently transfected with the reporter plasmid pGL4.47[luc2P/SIE/Hygro] (CAT no. E4041 Promega, Madison, WI, USA), a vector encoding the hLIFR (CAT no. RC226327) and CD130 (IL6ST) (CAT no.

(3) Digenic impairments of haploinsufficient genes in patients with craniosynostosisJCI InsightFebruary 24, 2025Jung Woo Yu, Jihoon G. Yoon, Chaerim Han, Shin Hye Noh, Dong Min Shin, Yu-Mi Yang, Yong Oock Kim, Kyu-Won Shim, Min Goo Leevariants (WT, N360S, and S580F) at a concentration of 200 ng/24 well. We used pGL4.47[luc2P/SIE/Hygro] (E4041, Promega), IL11RA (RC200654, OriGene), and pGL4.70[hRluc] (E6881, Promega) vectors to measure the activities

(4) Discovery of the Highly Selective and Potent STAT3 Inhibitor for Pancreatic Cancer TreatmentACS Central ScienceFebruary 10, 2024Huang Chen, Aiwu Bian, Wenbo Zhou, Ying Miao, Jiangnan Ye, Jiahui Li, Peng He, Qiansen Zhang, Yue Sun, Zhenliang Sun, et al.Table S3. Luciferase Reporter Assay The STAT3 luciferase plasmids (pGL4.47 luc2p/SIE/Hygro) vector (E4041, Promega) and Renilla plasmids were cotransfected into HEK293T with Lipofectamine 2000 reagent (Invitrogen)

(5) Discovery of BAR502, as potent steroidal antagonist of leukemia inhibitory factor receptor for the treatment of pancreatic adenocarcinomaFrontiers in oncologyJanuary 1, 2023Di Giorgio C, Bellini R, Lupia A, Massa C, Bordoni M, Marchianò S, Rosselli R, Sepe V, Rapacciuolo P, Moraca F, et al.cells were transiently transfected with the reporter plasmid pGL4.47[luc2P/SIE/Hygro] (200 ng) (CAT#: E4041 Promega, Madison, WI, USA), a vector encoding the hLIFR (CAT# RC226327) (100 ng) and CD130 (IL6ST) (100

(6) Repositioning Mifepristone as a Leukaemia Inhibitory Factor Receptor Antagonist for the Treatment of Pancreatic AdenocarcinomaCellsNovember 3, 2022Di Giorgio C, Lupia A, Marchianò S, Bordoni M, Bellini R, Massa C, Urbani G, Roselli R, Moraca F, Sepe V, et al.cells were transiently transfected with the reporter plasmid pGL4.47[luc2P/SIE/Hygro] (200 ng) (CAT#: E4041 Promega, Madison, WI, USA), a vector encoding the hLIFR (CAT# RC226327) (100 ng) and CD130 (IL6ST) (100

(7) Human STAT3 variants underlie autosomal dominant hyper-IgE syndrome by negative dominanceThe Journal of experimental medicineAugust 2, 2021Asano T, Khourieh J, Zhang P, Rapaport F, Spaan AN, Li J, Lei WT, Pelham SJ, Hum D, Chrabieh M, et al.was performed as previously described (Khourieh et al., 2019). Briefly, the reporter vector pGL4.47 (E4041; Promega) contains five copies of the STAT3-responsive element, the sis-inducible element, linked to

(8) The subcellular redistribution of NLRC5 promotes angiogenesis via interacting with STAT3 in endothelial cellsTheranosticsJanuary 1, 2021Xu X, Shi Y, Luan P, Kou W, Li B, Zhai M, You S, Yu Q, Zhuang J, Jian W, et al.assays pGL4.45 [luc2p/ISRE/Hygro] vector (REF# E414, Promega) and pGL4.47 [luc2p/SIE/Hygro] vector (REF# E4041, Promega) in combination with various vectors for luciferase assays were carried out using FuGene reagent

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pGL4.47[luc2P/SIE/Hygro] Vector from Promega

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pGL4.47[luc2P/SIE/Hygro] Vector from Promega

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