pGL4.52[luc2P/STAT5RE/Hygro] Vector from Promega

Product Specs
ItempGL4.52[luc2P/STAT5RE/Hygro] Vector
CompanyPromega
Price Supplier Page View Company Product Page
Catalog NumberE4651
Quantity20microg
Molecular Weight~73kDa
Nucleic Acid TypeReporter Vectors
Expression System (standardized)Mammalian
Vector NamepGL4.52[luc2P/STAT5RE/Hygro]

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Promega

2800 Woods Hollow Rd

Madison, WI 53711

United States

Phone: Tel: +1 (608) 274-4330
Fax: +1 (608) 277-2516

Email: custserv@promega.com
techserv@promega.com

Company Profile

Website: http://www.promega.com

(1) In silico modeling guides identification of novel JAK1 variants associated with immune dysregulationEMBO Molecular MedicineOctober 24, 2025Marie Jeanpierre, Orianne Debeaupuis, Camille Brunaud, Judith Yancoski, Quentin Riller, Jerome Hadjadj, Marie-Claude Stolzenberg, Giselle Villarreal, Marie Martha Katsicas, Mariana Villa, et al.plasmid encoding a 4× STAT6 binding site,"Sharma et al, 2024",N/A pGL4.52[luc2P/STAT5 RE/Hygro],Promega,E4651 pGL4[luc2P/GAS-RE/Hygro],Promega,CS179301 pGL4.45[luc2P/ISRE/Hygro],Promega,E4141 pTK-Green Renilla

(2) Hemizygous IL2RG Variants Impair IL-2-Induced STAT5 Phosphorylation and Transcriptional Activity Causing X-Linked Severe Combined ImmunodeficiencyThe Application of Clinical GeneticsSeptember 6, 2025Ning Zhang, Yi-Lin Sang, Wu Zhu, Yu-Rong Wang, Yan-Yan Yu, Ya-Hui Chen, Juan Du, Wen-Bin He, Yue-Qiu Tan, Fu-Yan Wangplasmids, Myc-tagged JAK3 vectors, and the pGL4.52 (Luc2P/STAT5RE/Hygro) reporter plasmid (Promega, E4651, Madison, WI, USA). After 36 hours, IL-2 (1000 U/mL) was added to the cultures and incubated for 40

(3) A PD-1-targeted, receptor-masked IL-2 immunocytokine that engages IL-2Rα strengthens T cell-mediated anti-tumor therapiesCell Reports MedicineOctober 15, 2024Jiaxi Wu, Nicolin Bloch, Aaron Y. Chang, Ramandeep Bhavsar, Qingqing Wang, Alison Crawford, David J. DiLillo, Kristin Vazzana, Katja Mohrs, Drew Dudgeon, et al.cells were electroporated with a STAT5 response element driven luciferase reporter construct (Promega, #E4651), single cell cloned and maintained in Iscove’s Medium (Irvine Scientific) supplemented with 20% FBS,

(4) A marine sponge-derived lectin reveals hidden pathway for thrombopoietin receptor activationNature CommunicationsNovember 25, 2022Hiromi Watari, Hiromu Kageyama, Nami Masubuchi, Hiroya Nakajima, Kako Onodera, Pamela J. Focia, Takumi Oshiro, Takashi Matsui, Yoshio Kodera, Tomohisa Ogawa, et al.reporter assay was performed as described previously21. Briefly, pcDNA3.1 with MPL cDNA, pGL4.52 (Promega #E4651), and pRL–TK (Promega #E2241) were co-transfected into HEK293T cells using lipofectamine 2000 (Invitrogen

(5) Glucocorticoids paradoxically facilitate steroid resistance in T cell acute lymphoblastic leukemias and thymocytesThe Journal of clinical investigationFebruary 3, 2020Meyer LK, Huang BJ, Delgado-Martin C, Roy RP, Hechmer A, Wandler AM, Vincent TL, Fortina P, Olshen AB, Wood BL, et al.CCRF-CEM cells were transiently transfected with the pGL4.52[luc2P/STAT5 RE/hygro] vector (Promega; E4651) using Lipofectamine 3000 Transfection Reagent (Life Technologies, Thermo Fisher Scientific). Eighteen

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