Fig 1: NOMO2/3 may be a target of PD. a Quantitative Venn diagram showing the overlapping proteins with significant alterations in BT-549 cells and MDA-MB-231 cells. NOMO2/3 was identified as the potential target of PD. b The mRNA level of NOMOs in PD-treated and untreated TNBC cells. There is no significant difference between treatment group and control. c The protein level of NOMO2 in PD-treated and untreated TNBC cells. PD could decrease the protein level of NOMO2. d The resulting IC50 values upon PD treatment of the individual NOMO2-overexpressed cell lines after 24 h. BT-549 and MDA-MB-231 cells were treated with indicated concentrations of PD. PD concentrations in b and c are IC50 for BT-549 and MDA-MB-231, respectively, and treatment duration is 24 h. All data were measured in three independent experiments