Ion Torrent™ Genexus™ Integrated Sequencer from Thermo Fisher Scientific

Product Specs
ItemIon Torrent™ Genexus™ Integrated Sequencer
CompanyThermo Fisher Scientific
Price Get Pricing Get Quote for this Product
Catalog NumberA45727
QuantityEA
ApplicationsNext Gen Sequencing, Small Whole Genome Sequencing, Targeted Sequencing, Amplicon Sequencing, Genotyping by Sequencing, Metagenomics, Single-genome microbial sequencing, Shotgun sequencing
Read Length100-400bp
Maximum Reads100M
Run Time19–24 hours (includes automated library prep)
Sample ThroughputUp to 48 samples with automated library preparation on instrument; 96 with manual library prep
Data AnalysisOnboard and cloud-based analysis tools with Genexus™ Software and other reporting tools.

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Thermo Fisher Scientific

168 Third Avenue

Waltham, MA 02451

United States

Phone: 781-622-1000

Company Profile

Website: thermofisher.com

(1) Patient‐derived surgical samples reveal the cellular and molecular signatures of glioblastoma infiltration in distinct radiological zonesBrain PathologyNovember 1, 2026Olaya de Dios, Juan Romero, María de los Ángeles Ramírez‐González, Beatriz Herranz, Alicia Avis‐Bodas, Juliana Manosalva, Diego Megías, Ana Ramos, Juan Manuel Sepúlveda‐Sánchez, Ricardo Gargini, et al.Ampliseq libraries were manually prepared using Ion AmpliSeq Library Kit Plus and sequenced on the Ion Torrent Genexus Integrated sequencer (Thermo Fisher). MGMT methylation status was assessed with the Pyromark Q24 kit (QIAGEN) (Appendix S2). 2.3

(2) Interpretation of p53 immunohistochemical stain of TP53-mutated myeloid neoplasmsFront OncolAugust 14, 2026Nawroz Barwari, William Patrick Morrow, Joni K. Evans, Nancy Rosenthal, Michael W. Beaty, Eric Hsi, Giovanni Insuasti-Beltran, Danielle L.V. Maracajanumber A50694, Thermo Fisher Scientific) on the Ion Torrent Genexus Integrated Sequencer (catalog number A45727, Thermo Fisher Scientific) using the Ion Torrent GX5™ semiconductor chip (catalog number A40269), according

(3) Unmasking Additional Mutations: A Single Institution Study in Myeloproliferative NeoplasmsCancers (Basel)July 31, 2026Parastou Tizro, Eric Vail, Manoj Sapkota, Matthew G. Gayhart, Celeste C. EnoNext-Generation Sequencing Clinical comprehensive molecular profiling was performed on submitted specimens using the Ion Torrent Genexus Integrated Sequencer (Genexus v2 platform; Thermo Fisher Scientific, Waltham, MA, USA). Library preparation, sequencing,

(4) EIF3E::RSPO2 Fusion in Metastatic Pancreatic Ductal Adenocarcinoma: A Clinical Case Report Suggesting a Putative KRAS-Independent Molecular ProfileInternational Journal of Molecular SciencesJune 24, 2026José María Sayagués, Mar Abad, Diego Bueno-Sacristán, Magdalena Sancho, María Belen Rivas, María Teresa Alonso-Márquez, Ana María Moreno, Juan Carlos Monteroplate, containing the nucleic acids and all reagents required for sequencing, was then loaded into the Ion Torrent™ Genexus™ Integrated Sequencer (Thermo Fisher Scientific), a fully automated NGS platform that performs library preparation, template

(5) Clinical Validation of a Rapid Automated Lymphoma Next-Generation Sequencing PanelAnnals of Laboratory MedicineMay 1, 2026Michael Krigstein, Emily Jude, Aleisha Jaffrey, Stephen Bye, Bin Wang, Min Ru Qiu, David MaAmpliSeq Liverpool Lymphoid Network Panel (IALLNP; Thermo Fisher Scientific, Waltham, MA, USA), using an Ion Torrent Genexus Integrated Sequencer (Thermo Fisher Scientific). The assay and workflow aim to provide rapid actionable results across the

(6) Integrating Rapid Lymphoma Next-Generation Sequencing Panel-Based Testing into Routine Genomic DiagnosticsAnn Lab MedMay 1, 2026Saeam Shin, Seung-Tae LeeAmpliSeq Liverpool Lymphoid Network Panel (IALLNP; Thermo Fisher Scientific, Waltham, MA, USA) on the Ion Torrent Genexus Integrated Sequencer (Thermo Fisher Scientific). The IALLNP is a commercially available amplicon-based DNA sequencing assay

(7) Clinical and genetic determinants of glioblastoma survival: a retrospective studyFrontiers in Molecular NeuroscienceFebruary 26, 2026Julia L. Gutiérrez-Arroyo, Pia Gallego-Porcar, Elvira Carbonell-Martinez, Luis G. González-Bonet, Maria Victoria Ibañez, María Díaz-Ruiz, Hugo Caballero-Arzapalo, Ariadna Soto, Guillermo Garcia-Oriola, Jose Maria Borras-Moreno, et al.the manufacturer’s instructions. Massive NGS sequencing was performed with Ion Torrent technology (Ion Torrent™ Genexus™ Integrated Sequencer) from Thermo Fisher Scientific (Waltham, MA, USA). The Oncomine Precision panel - GX5 - Solid Tumor

(8) Harmonization trial of FGFR1-3 testing strategies in cholangiocarcinoma patients: an Italian multicenter experiencePathologicaDecember 31, 2025Francesco Pepe, Gianluca Russo, Claudia Scimone, Lucia Palumbo, Stefania Tommasi, Rosamaria Pinto, Dario De Biase, Thais Maloberti, Adele Busico, Alessandra Santoro, et al.reference specimen were validated by the coordinator center adopting a fully automated NGS platform (Ion Torrent Genexus™ Integrated Sequencer, Thermo Fisher Scientific) that enables a single-step NGS workflow. This system was integrated with

(9) Harmonization trial of FGFR1-3 testing strategies in cholangiocarcinoma patients: an Italian multicenter experiencePathologicaDecember 31, 2025Francesco Pepe, Gianluca Russo, Claudia Scimone, Lucia Palumbo, Stefania Tommasi, Rosamaria Pinto, Dario De Biase, Thais Maloberti, Adele Busico, Alessandra Santoro, et al.reference specimen were validated by the coordinator center adopting a fully automated NGS platform (Ion Torrent Genexus™ Integrated Sequencer, Thermo Fisher Scientific) that enables a single-step NGS workflow. This system was integrated with

(10) Liquid Biopsy and Automated Next-Generation Sequencing: Achieving Results in 27 Hours Within a Community SettingDiagnostics (Basel)December 22, 2025Tomomi Yajima, Fumitake Hata, Sei Kurokawa, Kanan Sawamoto, Akiko Yajima, Daisuke Furuya, Noriyuki SatoEffective cfDNA input was assessed post-sequencing based on molecular coverage metrics generated by the Ion Torrent Genexus Integrated Sequencer (Thermo Fisher Scientific, Waltham, MA, USA); in this case, the median molecular coverage was 3669,

(11) RSPO3 rearrangements in advanced colorectal cancer patients and their relationship with disease characteristicsWorld Journal of Gastrointestinal OncologyNovember 15, 2025Raquel Tur, Mar Abad, Elena Filipovich, Maria Belen Rivas, Marta Rodriguez, Juan Carlos Montero, José María SayaguésStates). Finally, 20 μL of DNA and RNA (10 ng, quantified with qubit) were used for sequencing on the Ion Torrent™ Genexus™ Integrated Sequencer. This sequencer is a fully automated NGS system that integrates library preparation, template preparation,

(12) Emergence of the BA.2.87.1 lineage of SARS-CoV-2 in South Africa, a highly diverged BA.2-related lineageVirus EvolutionNovember 3, 2025Dikeledi Kekana, Buhle Ntozini, Ryan Hisner, Mukhlid Yousif, Phindile Ntuli, Nkosenhle Ndlovu, Kerrigan McCarthy, Anele Mnguni, Boitshoko Mahlangu, Ayanda Nzimande, et al.viral titre protocol. Sequencing was performed using the Ion AmpliSeq SARS-CoV-2 Research Panel on the Ion Torrent Genexus Integrated Sequencer (Thermo Fisher Scientific, Waltham, MA, USA), which combines automated complementary DNA (cDNA) synthesis,

(13) TTF-1 and p40 co-expression defines a distinct subtype of non-small cell lung cancer with frequent TP53 mutations and FGFR pathway dysregulationTranslational Lung Cancer ResearchSeptember 30, 2025Marcin Braun, Julia Sołek, Grzegorz Jerzy Stępień, Aleksandra Izabela Masłowska, Mateusz Kamecki, Paulina Antosik, Jacek Jassem, Bartłomiej Tomasik, Radzisław Kordekquantification via the built-in Qubit device. Samples yielding ≥5 ng of nucleic acid were transferred to the Ion Torrent Genexus Integrated Sequencer (Thermo Fisher Scientific) for targeted NGS using the Oncomine™ Precision Assay GX. This panel enables

(14) Comprehensive genetic profiling using tissue and blood in locally advanced tumorsOncol RepAugust 5, 2025Kenji Fujiyoshi, Rie Sugihara, Naoki Miyamoto, Yoriko Watanabe, Tomoya Sudo, Sanae Numata, Jun Akiba, Hideyuki Abe, Yuka Ichinose, Kenji Inoue, et al.somatic variants for targeted therapy and monitoring tumor evolution and resistance in real time (14). Ion Torrent™ Genexus™ Integrated Sequencer (Genexus, Thermo Fisher Scientific, Inc.) was developed to automate all targeted NGS workflows from

(15) Molecular landscape of HER2-mutated non-small cell lung cancer in Northeastern Brazil: Clinical, histopathological, and genomic insightsOncotargetJune 17, 2025Cleto Dantas Nogueira, Samuel Frota, Huylmer Lucena Chaves, Juliana Cordeiro de Sousa, Guilherme de Sousa Veloso, Francisco Jonathan dos Santos Araujo, Gabriel Barbosa Silva, Samuel Silva Ferreira, Marclesson Santos Alves, Fabio Nasser, et al.prior studies [43]. Next-generation sequencing Targeted sequencing was performed in-house using the Ion Torrent™ Genexus™ Integrated Sequencer (Thermo Fisher Scientific, Waltham, MA, USA) and the corresponding Oncomine Precision Assay (OPA). This

(16) Genome evolution of Kaposi sarcoma-associated herpesvirus (KSHV)Journal of VirologyMay 20, 2025Razia Moorad, Alice Peng, Justin Landis, Linda J. Pluta, Patricio Cano, Angelica Juarez, Dirk P. DittmerDNA library preparation and sequencing from plasma samples were performed using the automated approach on the Ion Torrent Genexus Integrated Sequencer (Thermo Fisher Scientific; Pub. No. MAN0017912), using custom primers to enrich for KSHV. For FFPE samples,

(17) Oligometastatic Renal Ewing Sarcoma With FUS::ERG Fusion: A Case Report And Literature ReviewSage Open PathologyMay 15, 2025Dan T. Nguyen, Trent Davidson, Fiona Maclean, Pranav Dorwal, Yeh Chen Lee, Min Ru Qiugenes using the Oncomine Precision Assay (Thermo Fischer Scientific, A46291) and was sequenced on the Ion Torrent Genexus Integrated Sequencer using the Ion Torrent GX5 Chip. The case was reviewed at 3 different laboratories (Douglass Hanly Moir

(18) High-Quality Samples for Next-Generation Sequencing and PD-L1 Assessment in Non-Small Cell Lung Cancer: The Role of Endobronchial Ultrasound-Guided Transbronchial Needle AspirationDiagnostics (Basel)April 22, 2025Marta Rodríguez González, Juan Carlos Montero González, José María Sayagués Manzano, Tamara Clavero Sánchez, Jonnathan Roldán Ruiz, Miguel Iglesias Heras, María Belén Rivas Marcos, Mar Abad Hernández, Rosa Cordovilla Pérezand Analysis Then, the mixture containing nucleic acids and sequencing reagents was loaded into the Ion Torrent™ Genexus™ Integrated Sequencer (Thermo Fisher Scientific; Waltham, MA, USA). The Oncomine Precision Assay (OPA) panel was used to detect

(19) A Novel Digital PCR Assay for Accurate Detection and Differentiation of Focal and Non-Focal Subtypes of Mesenchymal–Epithelial Transition (MET) Gene Amplification in Lung CancerCancers (Basel)February 26, 2025Raymond C. M. Shek, Peggy S. N. Li, Shelley C. M. Leung, H. T. Chu, F. Hioe, Victor W. L. Tang, Y. H. Lui, Larry R. S. Lam, Joshua H. Y. Ng, Raiden T. S. Wong, et al.Thermo Fisher Scientific Oncomine Precision Assay GX (Thermo Fisher Scientific, Inc., Waltham, MA, USA) on the Ion Torrent Genexus Integrated Sequencer (Thermo Fisher Scientific, Inc., Waltham, MA, USA), following the manufacturer’s instructions. This

(20) Genetic Profiling of Non-Small Cell Lung Cancer in Moroccan Patients by Targeted Next-Generation SequencingTechnology in Cancer Research & TreatmentOctober 4, 2024Sara El Zaitouni, Abdelilah Laraqui, Meriem Ghaouti, Asmae Benzekri, Fouad Kettani, Youssra Boustany, Soukaina Benmokhtar, Hafsa Lamrani Alaoui, Hicham El Annaz, Rachid Abi, et al.January 22, 2024. Sequencing Protocol The targeted sequencing of 76 FFPE samples was performed on the Ion Torrent™ Genexus™ Integrated Sequencer (Thermo Fisher Scientific, Waltham, MA, USA) using the (OPA, Thermo Fisher Scientific). A completely

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