Vega from Pacific Biosciences

Product Specs
ItemVega
CompanyPacific Biosciences
Price Inquire
Catalog NumberVega
Read Length0.5 to 20 kb
Maximum Reads10 M
Maximum Output60 Gb
Run Time12 to 24 hours
Sample ThroughputHuman genome (20x coverage), Microbial genome (30x coverage), Transcriptome (10 M reads), Amplicon (50x coverage)

Pacific Biosciences

Phone: 650.521.8000

Website: http://www.pacificbiosciences.com/

(1) DNV-TC: a developmental network vulnerability-based classification system for precision oncologyFront Cell Dev BiolSeptember 9, 2026Draga Toncheva, Vassil SgurevTCGA Illumina 450K methylation arrays. Oncogenic pathway activation scores were obtained from Sanchez-Vega et al. (2018) systematic pathway analysis. Protein–protein interaction networks were obtained from STRING

(2) Whole-genome sequencing of Bifidobacterium breve Y490 and Bifidobacterium longum subsp. infantis E16 isolated from infant fecesMicrobiology Resource AnnouncementsAugust 11, 2026Irene Boscá-Sánchez, Eva M. Moya-Gonzálvez, Jesús Rodríguez-Díaz, María J. Yebra7–10 kb, repaired, adapter-ligated, size-selected with AMPure PB beads, and sequenced on the PacBio VEGA System using VEGA polymerase-bound SMRTbell templates loaded onto a Vega SMRT Cell. Sequencing was conducted

(3) Research on genetic diversity and genomes of Miscanthus for optimizing their biotechnological potentialVavilovskii Zhurnal Genet SelektsiiJuly 1, 2026I.V. Chadaeva, D.I. Karetnikov, A.Yu. Pronozin, E.S. Starodubtseva, N.A. Omeljanchuk, A.V. Kochetov, D.A. Afonnikovgenome Samples from the diploid cultivar Robustus 297 were used for sequencing of the Msa genome (De Vega et al., 2021). Short-read libraries with small inserts generated using Illumina HiSeq 2500 platform

(4) Genome sequences of five Streptomyces type strains ( Streptomyces argenteolus , Streptomyces pratensis , Streptomyces puniceus , Streptomyces spiroverticillatus , and Streptomyces sundarbansensis )Microbiology Resource AnnouncementsJune 9, 2026Adrien Biessy, Anuradha Jayathissa, William Jordan, Megan Bennett, Molly Calo, Martin Filion(Pacific Biosciences) as per the manufacturer’s instructions. Genome sequencing was performed on a Vega sequencer (Pacific Biosciences) loaded with one Vega SMRT Cell (Vega chemistry). SMRT Link v25.3 (Pacific

(5) CIC–DUX4 Rearranged Gastric Sarcoma Confirmed by Next‐Generation Sequencing: A Case Report and Review of LiteratureClinical Case ReportsJune 1, 2026Hiroko Hasegawa, Atsushi Takeno, Rei Higashiura, Yuko Sakakibara, Mizuki Koba, Yumiko Hirose, Kiyoshi Mori, Motohiro Hirao, Masayuki Mano, Ryotaro Sakamori[15],1,Whole genome sequencing,Tibia,Overexpression of the translation factor eEF1A1 2,Lazo de la Vega et al. 2016 [16],8,Targeted NGS,Leg Shoulder Knee Forearm Pelvis Calf Flank Unknown,Low mutational burden

(6) Long-Read Sequencing in CKD Diagnostics: Breaking Genomic Barriers and Expanding Global InclusionKidney International ReportsMay 14, 2026Rafaella S. Barichello, Julia Y. Yun-Hsuan Hung, Andrew J. Mallett, Ulf Schmitzdetection through zero-mode waveguides. PacBio LRS platforms currently include the Sequel IIe, Revio, and Vega sequencers.22 Nanopore-based sequencing, developed by Oxford Nanopore Technologies (ONT; Oxford, UK),

(7) Isolation and Characterization of Bifidobacterium longum A1, an Isolate from Faeces of an Exclusively Breast-fed Infant with Probiotic PotentialProbiotics and Antimicrobial ProteinsApril 14, 2026Lise Sanchez, Marcus Vinicius Canario Viana, Veronique Robert, Florian Chain, Sead Chadi, Vasco Azevedo, Alexis Mosca, Philippe Langella, Sylvie Binda, Rebeca Martínmeasured using NanoDrop (NanoDrop 1,000, Thermo Fisher, USA). The genomes were sequenced using the PacBio VEGA platform (Pacific Biosciences) at the GeT-PlaGe core facility (GenoToul, INRAE, Toulouse, France), using

(8) Plant–soil–microbiome interactions: mechanisms, advances, and challenges in sustainable agriculture and healthy agroecosystemsFrontiers in MicrobiologyFebruary 20, 2026Jacek Panek, Agata Gryta, Wiktoria Maj, Mateusz Mącik, Karolina Oszust, Giorgia Pertile, Michał Pylak, Dominika Siegieda, Moritz Hallama, Ryusuke Hatano, et al.technologies, with PacBio offering Single-Molecule-Real-Time (SMRT) sequencing within its latest Revio and Vega platforms, while Oxford Nanopore Sequencing Technologies offers nanopore sequencing-based technology

(9) Phylogenetics and evolution of Digitaria grasses, including cereal crops fonio, raishan and Polish milletAnnals of BotanyJanuary 9, 2026George P Burton, Paolo Ceci, Lorna MacKinnon, Lizo E Masters, Noro Fenitra Harimbao Randrianarimanana, Philippa Ryan, Colin G N Turnbull, Tiziana Ulian, Maria S Vorontsovaand Sakai (2024). The topology is also supportive of the systematics proposed by the morphometrics of Vega et al. (2009) and the Sanger phylogenies of Lo Medico et al. (2017) and Morrone et al. (2012). However,

(10) Clinical applications of cell-free DNA-based liquid biopsy analysisTranslational OncologyNovember 1, 2025Shu Yazaki, Momoko Tokura, Hisaki Aiba, Yuki Kojima, Kouya ShiraishiDesign,Patients who are negative for postoperative ctDNA are randomized to adjuvant chemotherapy or to follow-up.,VEGA,jRCT1031200006,Colon,"High-risk stage II, low-risk stage III",Amplicon NGS,Signatera™,To demonstrate

(11) Novel mutations of maternal effect gene thyroid hormone receptor interactor 13 involved in biparental complete hydatidiform moleMedicine (Baltimore)October 24, 2025Qitao Zhan, Xinyun Yang, Yan Wangto cover over 99% of the variants in CCDS, ClinVar, Ensembl (CDS), miRBase, OMIM, RefSeq (CDS), and VEGA (CDS). Variants that were highly or potentially related to the patient’s phenotype were further verified

(12) Novel mutations of maternal effect gene thyroid hormone receptor interactor 13 involved in biparental complete hydatidiform moleMedicine (Baltimore)October 24, 2025Qitao Zhan, Xinyun Yang, Yan Wangto cover over 99% of the variants in CCDS, ClinVar, Ensembl (CDS), miRBase, OMIM, RefSeq (CDS), and VEGA (CDS). Variants that were highly or potentially related to the patient’s phenotype were further verified

(13) The Athlete Gut Microbiome: A Narrative Review of Multi-Omics Insights and Next-Generation Probiotic StrategiesNutrientsOctober 17, 2025Zhiwei Li, Youqiang Li, Yufei Wang, Jinjin Chen, Yilan Liuconfirmed by transcriptomics and proteomics,Fecal stool,Illumina NextSeq 2000/NovaSeq for shotgun; PacBio Vega or ONT PromethION for long-reads,Moderate ($$),"Reveals which microbes are present and the functional

(14) Why Are Long-Read Sequencing Methods Revolutionizing Microbiome Analysis?MicroorganismsAugust 9, 2025Adriana González, Asier Fullaondo, Adrian Odriozolai100 to 19.08 Gb/h for NovaSeq 6000. PacBio platforms showed comparable speeds, achieving 2.5 Gb/h for Vega and 20 Gb/h for Revio. Finally, the ONT systems showed theoretical sequencing speeds ranging from 0.16

(15) Get ready for short tandem repeats analysis using long reads-the challenges and the state of the artFront GenetJuly 2, 2025Marija Chaushevska, Karmele Alapont-Celaya, Anne Kristine Schack, Lukasz Krych, M. Carmen Garrido Navas, Anastasia Krithara, Gjorgji Madjarovepigenetic profiling by enabling direct detection of 5 mC and 6 mA modifications. Additionally, PacBio’s Vega system Pacific Biosciences (2024), announced in 2024, offers a benchtop long-read sequencer designed

(16) Long-read sequencing for diagnosis of genetic myopathiesBMJ Neurol OpenMay 11, 2025Dennis Yeow, Laura Ivete Rudaks, Ryan Davis, Karl Ng, Roula Ghaoui, Pak Leng Cheong, Gianina Ravenscroft, Marina Kennerson, Ira Deveson, Kishore Raj KumarLRS platforms support projects of various sizes, with mid-throughput bench-top instruments (PacBio Vega; ONT GridION or P2) and high-throughput instruments (PacBio Revio; ONT PromethION P24 or P48) now available. Like

(17) Leveraging long-read sequencing technologies for pharmacogenomic testing: applications, analytical strategies, challenges, and future perspectivesFrontiers in GeneticsApril 30, 2025Alireza Tafazoli, Mahboobeh Hemmati, Mahboobeh Rafigh, Maliheh Alimardani, Faeze Khaghani, Michał Korostyński, Jason H. KarnesBiological Studies., 2024 Pacific Biosciences., Revio System Brochure., 2023",HiFi (High-Fidelity),Vega benchtop system,"∼$1,500 to $3,000 per sample" Pacific Biosciences (PacBio)-Single Molecule Real-Time

(18) Clinical utility and future perspectives of liquid biopsy in colorectal cancerCommunications MedicineApril 24, 2025Giorgio Patelli, Luca Lazzari, Giovanni Crisafulli, Andrea Sartore-Bianchi, Alberto Bardelli, Salvatore Siena, Silvia MarsoniDFS,TRACC/ NCT04050345,De-escalation if MRD-,III,II/III,1000,Blood-based ddPCR,2016–2031 3-year DFS,III,VEGA/ JRCT1031200006,Escalation if MRD+,>1000,Tissue-based NGS,2020–2025 3-year DFS,III,Escalation if MRD+,PRODIGE

(19) Exploration of Neurodegenerative Diseases Using Long‐Read Sequencing and Optical Genome Mapping TechnologiesMovement DisordersMarch 3, 2025Guillaume Cogan, Kensuke Daida, Cornelis Blauwendraat, Kimberley Billingsley, Alexis Briceavailable platforms for PacBio include RS, RSII, Sequel, Sequel II, Revio, and, most recently, the Vega system. MinION, PromethION, GridION, and SmidgION are provided by ONT. Although ONT initially had a

(20) Plasma ctDNA kinetics as a predictor of systemic therapy response for advanced non-small cell lung cancer: a systematic review and meta-analysisThe OncologistFebruary 25, 2025Luís F Leite da Silva, Erick F Saldanha, Júnior Samuel Alonso de Menezes, Leonardo Halamy Pereira, João Alexandre R de Bragança dos Santos, Isabella Romagnoli Buonopane, Erito M de Souza, Caio Ulysses Galvani de Menezes, Gilberto Lopescohort,n/a,67,ICB,"NGS, tumor agnostic" "van der Leest, 2021",Prospective cohort,n/a,100,ICB,"PCR, tumor informed" "Vega, 2021",Clinical trial,n/a,200,ICB,"NGS, tumor agnostic" "Wang, 2018",Prospective cohort,EGFR,183,EGFR

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Vega

Vega from Pacific Biosciences

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Vega from Pacific Biosciences

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